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The map label for this gene is cobL [H]

Identifier: 148823287

GI number: 148823287

Start: 2343586

End: 2344758

Strand: Reverse

Name: cobL [H]

Synonym: TBFG_12108

Alternate gene names: 148823287

Gene position: 2344758-2343586 (Counterclockwise)

Preceding gene: 148823288

Following gene: 148823286

Centisome position: 53.0

GC content: 68.29

Gene sequence:

>1173_bases
ATGATCATCGTTGTCGGGATCGGCGCCGACGGCATGACCGGTCTCTCCGAGCATTCTCGCTCCGAATTGCGCAGGGCCAC
AGTAATTTACGGCTCGAAACGGCAACTTGCCCTGCTCGACGATACCGTCACCGCCGAGCGCTGGGAGTGGCCGACGCCGA
TGCTGCCCGCGGTGCAAGGCCTGTCACCGGATGGGGCTGACCTACACGTGGTTGCCAGCGGCGACCCGTTGTTGCATGGT
ATCGGCTCCACCCTGATCCGGCTGTTCGGCCACGACAACGTGACCGTGTTGCCGCACGTGTCCGCGGTGACGTTGGCGTG
CGCCCGGATGGGCTGGAACGTGTATGACACCGAGGTGATCAGCCTGGTCACCGCGCAACCACACACCGCGGTGCGCCGCG
GCGGCCGGGCCATCGTGCTGTCCGGCGATCGGTCCACCCCGCAGGCGCTGGCGGTGCTGCTGACCGAGCACGGTCGCGGT
GACTCCAAGTTCAGCGTGCTCGAACAGCTTGGCGGCCCGGCCGAACGCCGCCGCGACGGTACGGCCCGGGCATGGGCCTG
CGACCCACCCCTCGATGTCGATGAGCTCAACGTGATCGCCGTGCGCTACCTGCCCGACGAGCGCACGTCGTGGGCACCCG
ACGAGGCATTCGCGCACGACGGGCAGATCACCAAACACCCGATCCGCGTGCTGACCCTGGCTGCGCTGGCGCCAAGGCCC
GGGCAGCGGTTATGGGACGTCGGCGCGGGCTCAGGCGCCATCGCGGTCCAGTGGTGTCGGAGCTGGCCGGGCTGCACCGC
GGTGGCGTTCGAGCGCGACGAACGGCGCCGCCGCAACATTGGGTTCAATGCCGCGGCCTTCGGGGTGAGCGTCGACGTGC
GCGGCGACGCGCCCGATGCGTTCGACGACGCCGCACGGCCGTCGGTGATTTTTCTTGGCGGTGGTGTAACCCAGCCAGGC
CTGCTTGAGGCCTGCCTGGACAGCCTGCCCGCAGGCGGGAACTTGGTCGCCAACGCTGTCACCGTCGAATCGGAAGCCGC
TCTGGCGCATGCATATTCGCGCCTCGGTGGCGAGCTACGACGATTCCAGCACTATCTCGGCGAACCGCTGGGCGGCTTCA
CCGGTTGGCGCCCACAGCTGCCGGTCACCCAGTGGTCGGTGACCAAGCGATGA

Upstream 100 bases:

>100_bases
CCCCGGTTCGTCTGGCGCAGGATGCCGCGATGATCCGCGACGATGCAGAGCGCAGCGATGCGGTGGGGGTACCGCCCGCT
TGCGGGGGAGAGCGGCGCCG

Downstream 100 bases:

>100_bases
CGGTCTATTTCATCGGAGCGGGCCCCGGCGCCGCCGACCTAATCACCGTCCGCGGCCAACGGCTCCTGCAACGATGCCCG
GTGTGCCTGTATGCGGGTTC

Product: precorrin-6y methyltransferase cobL

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHG
IGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRG
DSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRP
GQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPG
LLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR

Sequences:

>Translated_390_residues
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHG
IGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRG
DSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRP
GQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPG
LLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
>Mature_390_residues
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHG
IGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRG
DSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRP
GQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPG
LLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 41839; Mature: 41839

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG
CEEEEEECCCCCCCCHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHCC
LSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVI
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCEECCEEE
SLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDG
EEEECCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCC
TARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRP
CCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCC
GQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDA
CCCEEECCCCCCCEEEEEHHCCCCCEEEEECCHHHHHHCCCCCEEEEEEEEEECCCCCCC
FDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELR
HHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHH
RFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG
CEEEEEECCCCCCCCHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHCC
LSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVI
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCEECCEEE
SLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDG
EEEECCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCC
TARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRP
CCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCC
GQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDA
CCCEEECCCCCCCEEEEEHHCCCCCEEEEECCHHHHHHCCCCCEEEEEEEEEECCCCCCC
FDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELR
HHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHH
RFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]