Click here to switch to the map view.

The map label for this gene is esxF

Identifier: 148663772

GI number: 148663772

Start: 4399166

End: 4399477

Strand: Reverse

Name: esxF

Synonym: MRA_3944

Alternate gene names: NA

Gene position: 4399477-4399166 (Counterclockwise)

Preceding gene: 148663773

Following gene: 148663771

Centisome position: 99.54

GC content: 68.27

Gene sequence:

>312_bases
ATGGGTGCCGACGACACGCTGCGCGTAGAGCCTGCGGTGATGCAGGGTTTCGCCGCGTCGTTGGATGGAGCGGCCGAGCA
TCTCGCGGTTCAACTGGCCGAGCTGGACGCTCAGGTCGGGCAGATGTTGGGCGGGTGGCGCGGGGCGTCGGGCAGTGCGT
ATGGCTCGGCGTGGGAGCTATGGCATCGCGGGGCCGGTGAGGTGCAGCTGGGATTGTCGATGCTGGCGGCGGCGATAGCT
CACGCCGGTGCGGGTTATCAACACAACGAGACCGCGTCGGCGCAGGTGCTTCGTGAGGTGGGCGGTGGCTGA

Upstream 100 bases:

>100_bases
GCGACGGCACCGCCGACGGCGCCAGCAGCCTTTAGGGCTGCGGCGGGTGCGCCCGGGCGGCTGAATTGTGGCGGTGCCTG
GGCATTGTTAGGTTGCGGCC

Downstream 100 bases:

>100_bases
GCCGTTTCGGGTGGATCCGACCGTGTTGGCTGATGCGGTGGCGCGGATGGCCGAATTCGGTCGCCACGTCGAGGAGCTGG
TCGCCGAGATTGAGTCCTTG

Product: putative esat-6 like protein EsxF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MGADDTLRVEPAVMQGFAASLDGAAEHLAVQLAELDAQVGQMLGGWRGASGSAYGSAWELWHRGAGEVQLGLSMLAAAIA
HAGAGYQHNETASAQVLREVGGG

Sequences:

>Translated_103_residues
MGADDTLRVEPAVMQGFAASLDGAAEHLAVQLAELDAQVGQMLGGWRGASGSAYGSAWELWHRGAGEVQLGLSMLAAAIA
HAGAGYQHNETASAQVLREVGGG
>Mature_102_residues
GADDTLRVEPAVMQGFAASLDGAAEHLAVQLAELDAQVGQMLGGWRGASGSAYGSAWELWHRGAGEVQLGLSMLAAAIAH
AGAGYQHNETASAQVLREVGGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ES6LD_MYCTU (O05440)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   B70600
- RefSeq:   NP_218422.1
- RefSeq:   NP_338574.1
- ProteinModelPortal:   O05440
- SMR:   O05440
- EnsemblBacteria:   EBMYCT00000002805
- EnsemblBacteria:   EBMYCT00000073061
- GeneID:   886239
- GeneID:   922516
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT4024
- KEGG:   mtu:Rv3905c
- TIGR:   MT4024
- TubercuList:   Rv3905c
- GeneTree:   EBGT00050000015030
- HOGENOM:   HBG564998
- OMA:   FASAWEL
- ProtClustDB:   CLSK792803
- InterPro:   IPR010310

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 10460; Mature: 10329

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADDTLRVEPAVMQGFAASLDGAAEHLAVQLAELDAQVGQMLGGWRGASGSAYGSAWEL
CCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
WHRGAGEVQLGLSMLAAAIAHAGAGYQHNETASAQVLREVGGG
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GADDTLRVEPAVMQGFAASLDGAAEHLAVQLAELDAQVGQMLGGWRGASGSAYGSAWEL
CCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
WHRGAGEVQLGLSMLAAAIAHAGAGYQHNETASAQVLREVGGG
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036