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The map label for this gene is esxE

Identifier: 148663771

GI number: 148663771

Start: 4398883

End: 4399155

Strand: Reverse

Name: esxE

Synonym: MRA_3943

Alternate gene names: NA

Gene position: 4399155-4398883 (Counterclockwise)

Preceding gene: 148663772

Following gene: 148663770

Centisome position: 99.53

GC content: 67.03

Gene sequence:

>273_bases
GTGGATCCGACCGTGTTGGCTGATGCGGTGGCGCGGATGGCCGAATTCGGTCGCCACGTCGAGGAGCTGGTCGCCGAGAT
TGAGTCCTTGGTTACCCGGCTGCATGTGACGTGGACGGGGGAGGGCGCGGCGGCTCATGCTGAGGCGCAACGACATTGGG
CTGCCGGTGAGGCGATGATGCGCCAGGCGTTGGCCCAGCTCACGGCCGCGGGGCAGAGCGCGCACGCCAACTACACCGGC
GCGATGGCCACGAATTTGGGTATGTGGTCGTGA

Upstream 100 bases:

>100_bases
CTGGCGGCGGCGATAGCTCACGCCGGTGCGGGTTATCAACACAACGAGACCGCGTCGGCGCAGGTGCTTCGTGAGGTGGG
CGGTGGCTGAGCCGTTTCGG

Downstream 100 bases:

>100_bases
GCTGATGGCGCCGTTGGCGGTCGATCCCGCGGCCCTTGATAGCGCGGGCGGCGCGGTGGTGGCTGCGGGTGCGGGTTTGG
GTGCGGTGATCTCGTCGCTG

Product: putative esat-6 like protein EsxE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MDPTVLADAVARMAEFGRHVEELVAEIESLVTRLHVTWTGEGAAAHAEAQRHWAAGEAMMRQALAQLTAAGQSAHANYTG
AMATNLGMWS

Sequences:

>Translated_90_residues
MDPTVLADAVARMAEFGRHVEELVAEIESLVTRLHVTWTGEGAAAHAEAQRHWAAGEAMMRQALAQLTAAGQSAHANYTG
AMATNLGMWS
>Mature_90_residues
MDPTVLADAVARMAEFGRHVEELVAEIESLVTRLHVTWTGEGAAAHAEAQRHWAAGEAMMRQALAQLTAAGQSAHANYTG
AMATNLGMWS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ES6LC_MYCTU (O05441)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   A70600
- RefSeq:   NP_218421.1
- RefSeq:   NP_338573.1
- ProteinModelPortal:   O05441
- SMR:   O05441
- EnsemblBacteria:   EBMYCT00000001398
- EnsemblBacteria:   EBMYCT00000072716
- GeneID:   886237
- GeneID:   926648
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT4023
- KEGG:   mtu:Rv3904c
- TIGR:   MT4023
- TubercuList:   Rv3904c
- GeneTree:   EBGT00050000016755
- HOGENOM:   HBG580437
- OMA:   WHGEASD
- ProtClustDB:   CLSK792802
- InterPro:   IPR010310

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 9603; Mature: 9603

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPTVLADAVARMAEFGRHVEELVAEIESLVTRLHVTWTGEGAAAHAEAQRHWAAGEAMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
RQALAQLTAAGQSAHANYTGAMATNLGMWS
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MDPTVLADAVARMAEFGRHVEELVAEIESLVTRLHVTWTGEGAAAHAEAQRHWAAGEAMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
RQALAQLTAAGQSAHANYTGAMATNLGMWS
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036