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The map label for this gene is ppe66

Identifier: 148663604

GI number: 148663604

Start: 4197731

End: 4198678

Strand: Reverse

Name: ppe66

Synonym: MRA_3776

Alternate gene names: 148663604

Gene position: 4198678-4197731 (Counterclockwise)

Preceding gene: 148663605

Following gene: 148663600

Centisome position: 94.99

GC content: 64.24

Gene sequence:

>948_bases
ATGACCACGGCATATGCCAGCGCGCTGGCGGCGATGCCGACGCTGACCGAGTTGGCCGCTAATCACACCAGCCATGCGGT
GTTGCTGGGAACGAATTTCTTTGGAATCAATACGATCCCGATCGCGCTCAATGAGGCCGACTATGCGCGGATGTGGATTC
AGGCGGCCACCACGATGAGTATCTATGAGGGCACCTCCGATGCGGCGCTGGCGTCGGCACCGCAAACCACACCGGCTCCG
GTACTGTTCAACGGCGGTGCTGGCGTTGCCAGCGCCCTGCCGGCGATCTCCGCCGCAACGTTGGACCCCGCCAGCATCAT
CGGGATCATCATCGAGATATTGATTCAGCTCTTTCTGATATCGCTCGAGATCCTGTTTGCAATCGTCGCATACACGATCA
TCATCGTGCTCATCTTGCCGCTCGTGATCTTCGCATACGCGATCGTCTTTGCGGTCCTGGCGATCATCTTCGGCCCGCCG
CTCCTTGTGATCGCATCGCCATTTGTGCTCACCGGCTCCGTGATTGCGGTGCCGACCTCGTTGTCGACTTCGTTGTCGAC
TGCGGTGCCTATCGGCGTTGGCCAGTACCTCGCGGACCTGGCGAGTGCGGACGCGCAGGCTATCGAAGTGGGCCTAAAGA
CGGCGGACGTGGCGCCCGTTGCCGTACGACCTGCAGCGGCGCCGCCGTTGCGTGAGTCTGCCGCGGTGCGACCGGAGGCC
AGGCTGGTGTCGGCGGTGGCGCCAGCTCCCGCGGGCACGTCGGCGTCGGTGCTGGCTTCGGATCGGGGTGCCGGCGTGTT
GGGGTTTGCCGGGACCGCTGGCAAGGAGTCCGTTGGGCGTCCTGCGGGGTTGACCACGTTGGCCGGTGGTGAGTTCGGGG
GTAGTCCGTCGGTGCCGATGGTGCCCGCTAGCTGGGAGCAGTTGGTCGGCGCTGGCGAGGCTGGCTAG

Upstream 100 bases:

>100_bases
TCCGAGCGCCGAAGCTTATGTGGCCGCCCACCTACCTTATCTAGCCTAGCTAACTAAATCCAGTGCCGACAGTGCGCGGC
TGGCCACCCAGCATGAGGTT

Downstream 100 bases:

>100_bases
CGCACCTCGGTCGCGCTGGTGCAGGTAGCGGGCCAATCGCCGCGATAGCCGGCGTCCACGTCGTCGGCCGTCGTCGGCTC
CAGCGCGACGCTTCGCCACC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTTAYASALAAMPTLTELAANHTSHAVLLGTNFFGINTIPIALNEADYARMWIQAATTMSIYEGTSDAALASAPQTTPAP
VLFNGGAGVASALPAISAATLDPASIIGIIIEILIQLFLISLEILFAIVAYTIIIVLILPLVIFAYAIVFAVLAIIFGPP
LLVIASPFVLTGSVIAVPTSLSTSLSTAVPIGVGQYLADLASADAQAIEVGLKTADVAPVAVRPAAAPPLRESAAVRPEA
RLVSAVAPAPAGTSASVLASDRGAGVLGFAGTAGKESVGRPAGLTTLAGGEFGGSPSVPMVPASWEQLVGAGEAG

Sequences:

>Translated_315_residues
MTTAYASALAAMPTLTELAANHTSHAVLLGTNFFGINTIPIALNEADYARMWIQAATTMSIYEGTSDAALASAPQTTPAP
VLFNGGAGVASALPAISAATLDPASIIGIIIEILIQLFLISLEILFAIVAYTIIIVLILPLVIFAYAIVFAVLAIIFGPP
LLVIASPFVLTGSVIAVPTSLSTSLSTAVPIGVGQYLADLASADAQAIEVGLKTADVAPVAVRPAAAPPLRESAAVRPEA
RLVSAVAPAPAGTSASVLASDRGAGVLGFAGTAGKESVGRPAGLTTLAGGEFGGSPSVPMVPASWEQLVGAGEAG
>Mature_314_residues
TTAYASALAAMPTLTELAANHTSHAVLLGTNFFGINTIPIALNEADYARMWIQAATTMSIYEGTSDAALASAPQTTPAPV
LFNGGAGVASALPAISAATLDPASIIGIIIEILIQLFLISLEILFAIVAYTIIIVLILPLVIFAYAIVFAVLAIIFGPPL
LVIASPFVLTGSVIAVPTSLSTSLSTAVPIGVGQYLADLASADAQAIEVGLKTADVAPVAVRPAAAPPLRESAAVRPEAR
LVSAVAPAPAGTSASVLASDRGAGVLGFAGTAGKESVGRPAGLTTLAGGEFGGSPSVPMVPASWEQLVGAGEAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE66_MYCTU (Q79FA3)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   C70798
- RefSeq:   YP_178009.1
- ProteinModelPortal:   Q79FA3
- SMR:   Q79FA3
- EnsemblBacteria:   EBMYCT00000001053
- EnsemblBacteria:   EBMYCT00000084054
- GeneID:   886262
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv3738c
- TIGR:   MT3844
- TubercuList:   Rv3738c
- GeneTree:   EBGT00050000014875
- HOGENOM:   HBG572308
- OMA:   FLILVEA
- ProtClustDB:   CLSK836747
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 31436; Mature: 31305

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2277da44)-; HASH(0x22509b80)-; HASH(0x22545d40)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAYASALAAMPTLTELAANHTSHAVLLGTNFFGINTIPIALNEADYARMWIQAATTMS
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCEECCEEEEEEECCCHHHHHHHHHHHHHE
IYEGTSDAALASAPQTTPAPVLFNGGAGVASALPAISAATLDPASIIGIIIEILIQLFLI
EECCCCCCHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SLEILFAIVAYTIIIVLILPLVIFAYAIVFAVLAIIFGPPLLVIASPFVLTGSVIAVPTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCEEEECCC
LSTSLSTAVPIGVGQYLADLASADAQAIEVGLKTADVAPVAVRPAAAPPLRESAAVRPEA
CCHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCEEECCCCCCCCCHHCCCCCHH
RLVSAVAPAPAGTSASVLASDRGAGVLGFAGTAGKESVGRPAGLTTLAGGEFGGSPSVPM
HHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCCHHCCCCCCCEEECCCCCCCCCCCCC
VPASWEQLVGAGEAG
CCCCHHHHHCCCCCH
>Mature Secondary Structure 
TTAYASALAAMPTLTELAANHTSHAVLLGTNFFGINTIPIALNEADYARMWIQAATTMS
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECCEECCEEEEEEECCCHHHHHHHHHHHHHE
IYEGTSDAALASAPQTTPAPVLFNGGAGVASALPAISAATLDPASIIGIIIEILIQLFLI
EECCCCCCHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SLEILFAIVAYTIIIVLILPLVIFAYAIVFAVLAIIFGPPLLVIASPFVLTGSVIAVPTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCEEEECCC
LSTSLSTAVPIGVGQYLADLASADAQAIEVGLKTADVAPVAVRPAAAPPLRESAAVRPEA
CCHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCEEECCCCCCCCCHHCCCCCHH
RLVSAVAPAPAGTSASVLASDRGAGVLGFAGTAGKESVGRPAGLTTLAGGEFGGSPSVPM
HHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCCHHCCCCCCCEEECCCCCCCCCCCCC
VPASWEQLVGAGEAG
CCCCHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036