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The map label for this gene is PE_PGRS35 [H]

Identifier: 148660530

GI number: 148660530

Start: 847474

End: 849219

Strand: Direct

Name: PE_PGRS35 [H]

Synonym: MRA_0763

Alternate gene names: 148660530

Gene position: 847474-849219 (Clockwise)

Preceding gene: 148660526

Following gene: 148660534

Centisome position: 19.17

GC content: 68.73

Gene sequence:

>1746_bases
GTGATCGTGGCGCGGGACGCGTTGGCGGCGGCCGCGGCGGATCTAGCGCAGATCGGTTCGGCAGTGAATGCGGGCAATCT
GGCCGCAGCCAATCCGACGACCGCTGTGGCGGCGGCGGCCGCCGACGAGGTATCGGCGGCACTCGCGGCGCTGTTCGGCG
CGCATGCCCGGGAGTATCAGGCGGCGGCGGCGCAGGCAGCGGCGTATCACGAGCAGTTTGTGCACCGATTGAGCGCGGCA
GCGACATCGTATGCGGTTACCGAGGTGACCATCGCGACGTCGCTCCGGGGGGCGCTGGGCTCGGCGCCCGCGTCCGTTTC
CGACGGGTTCCAAGCGTTCGTCTATGGTCCGATTCACGCGACCGGCCAGCAATGGATCAACAGCCCGGTCGGCGAGGCGC
TCGCCCCGATTGTCAATGCGCCGACAAACGTGCTGCTCGGCCGCGATCTGATCGGCAACGGCGTCACCGGGACGGCGGCA
GCTCCCAACGGTGGCCCCGGCGGTTTGCTATTCGGTGACGGTGGGGCCGGCTATACCGGCGGTAACGGTGGGAGTGCCGG
GTTAATCGGCAACGGGGGTACCGGTGGCGCCGGCTTTGCCGGCGGAGTGGGCGGCATGGGCGGCACCGGCGGCTGGTTGA
TGGGCAACGGCGGCATGGGTGGCGCGGGCGGTGTCGGCGGTAACGGCGGCGCCGGGGGCCAGGCGCTGTTGTTCGGCAAC
GGCGGCCTGGGCGGAGCCGGCGGGGCTGGCGGGGTCGATGGGGCTATCGGTCGTGGCGGGTGGTTCATCGGTACCGGCGG
CATGGCCACGATCGGTGGTGGCGGCAACGGGCAGTCGATCGTCATCGACTTCGTGCGGCACGGCCAGACGCCGGGCAACG
CCGCAATGTTGATCGACACGGCGGTGCCCGGACCCGGACTCACCGCGCTGGGCCAGCAACAGGCGCAGGCCATCGCCAAC
GCGCTCGCGGCCAAGGGCCCCTATGCCGGGATCTTCGACTCGCAGTTGATCAGAACGCAGCAGACCGCCGCGCCGTTGGC
GAACTTGCTGGGGATGGCCCCGCAGGTATTGCCCGGGCTCAACGAGATCCATGCCGGCATCTTCGAGGACCTGCCGCAGA
TCAGCCCCGCGGGCCTGCTGTATCTCGTCGGCCCGATCGCCTGGACGCTCGGATTTCCCATCGTGCCGATGCTGGCCCCG
GGCTCCACCGACGTCAACGGGATCGTCTTCAACCGAGCCTTTACCGGTGCGGTTCAAACGATCTACGACGCTTCCTTGGC
CAATCCGGTCGTGGCCGCAGACGGCAACATCACGTCGGTCGCTTACTCCAGCGCATTCACCATCGGGGTCGGGACGATGA
TGAACGTCGACAATCCCCATCCGCTACTGCTGCTCACCCACCCGGTGCCCAACACCGGCGCCGTCGTGGTACAGGGCAAT
CCCGAGGGCGGCTGGACGCTGGTCAGCTGGGACGGGATACCCGTCGGGCCGGCGTCGCTGCCGACCGCGTTATTCGTCGA
CGTGCGCGAGCTGATCACGGCGCCGCAATATGCGGCCTACGACATTTGGGAGTCCCTGTTCACCGGCGATCCGGCGGCGG
TCATCAACGCGGTGCGAGACGGTGCCGATGAGGTCGGCGCGGCTGTGGTCCAGTTCCCACATGCGGTGGCTGACGACGTG
ATCGACGCTACGGGCCACCCCTATCTAAGCGGCCTGCCGATCGGTCTGCCCAGCCTGATCCCATGA

Upstream 100 bases:

>100_bases
TGGATGCTCGTTGCATTTTGGCCGATACCCGCATCTGTTCCGGCGCTGCGCTCCATCATGGCTAGTACGCGACAACACCC
GGGGGTAAGCGATGTCATTT

Downstream 100 bases:

>100_bases
CCGCGAGCGACCAATAGGTCCCCACATGGCCCGGAGGCCGCTGCCAGCATTGACCCGACGATGCCGGCCCGCAGGCTTCC
CTGATCGTGCGGAACCTGCT

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRLSAA
ATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAA
APNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGN
GGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQAIAN
ALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAP
GSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGN
PEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVADDV
IDATGHPYLSGLPIGLPSLIP

Sequences:

>Translated_581_residues
MIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRLSAA
ATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAA
APNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGN
GGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQAIAN
ALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAP
GSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGN
PEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVADDV
IDATGHPYLSGLPIGLPSLIP
>Mature_581_residues
MIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRLSAA
ATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAA
APNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGN
GGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQAIAN
ALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAP
GSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGN
PEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVADDV
IDATGHPYLSGLPIGLPSLIP

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 56612; Mature: 56612

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQ
CEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
TGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAGYTG
CHHHHHCCHHHHHHHHHHCCCCCEEECCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGN
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEC
GGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDT
CCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCEEEEEHHHCCCCCCCEEEEEEE
AVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCH
NEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGAVQT
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECHHHHHHHH
IYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGN
HHHHHHCCCEEECCCCEEEEEECCEEEEECCEEEECCCCCCEEEEECCCCCCCEEEEEEC
PEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRD
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHC
GADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP
CHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQ
CEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
TGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAGYTG
CHHHHHCCHHHHHHHHHHCCCCCEEECCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGN
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEC
GGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDT
CCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCEEEEEHHHCCCCCCCEEEEEEE
AVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCH
NEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGAVQT
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECHHHHHHHH
IYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGN
HHHHHHCCCEEECCCCEEEEEECCEEEEECCEEEECCCCCCEEEEECCCCCCCEEEEEEC
PEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRD
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHC
GADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP
CHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]