Click here to switch to the map view.

The map label for this gene is fadE9 [H]

Identifier: 148660528

GI number: 148660528

Start: 844548

End: 845720

Strand: Reverse

Name: fadE9 [H]

Synonym: MRA_0761

Alternate gene names: 148660528

Gene position: 845720-844548 (Counterclockwise)

Preceding gene: 148660529

Following gene: 148660527

Centisome position: 19.13

GC content: 66.84

Gene sequence:

>1173_bases
ATGTTTGTCCTTAACGACGACGAACGGGTGATCGTCGAGACGGCGGCCGCCTTCGCCGGCAAACGCCTGGCTCCGCACGC
CCTGGAATGGGATGCCGCCAAACACTTTCCGGTGGACGTGTTGCGGGAAGCGGCCGAACTCGGCATGGCCGCGATCTATT
GCCGCGACGACGTCGGCGGCAGTGGGCTGCGCCGGCTCGACGGCGTGCGCATCTTCGAGCAGTTGGCGATCGCCGACCCG
GTGACCGCCGCGTTTTTGTCCATCCACAACATGTGCGCGTGGATGATTGACAGCTTCGGCACCGACGAGCAACGCAAGGA
CTGGATTCCGCGACTGGCCACCATGGGCGTCATCGCCAGCTACTGCCTGACCGAACCGGGCGCCGGATCCGATGCCGGCG
CACTGAGCACCCGCGCCGTCAGGCACGGCTCAGGAAAAGGCGGCGACTACGTGCTCGATGGCGTCAAACAATTCATTTCC
GGGGCCGCAGCATCGGACGTGTATGTGGTGATGGCGCGCACGGGCGCCGAGGGTCCGCGCGGCGTGTCGGCGTTCATCGT
CGAAAAGGGCACACCGGGGCTGAGTTTCGGCGCGCCCGAAGCGAAGATGGGTTGGCATGCCCAACCCACCGCGCAGGTGG
TGCTGGACGGGGTGCGGGTACCCGCCGAGGCCATGCTGGGCGGCGCCGACGGCGAAGGCGCCGGCTTCGGTATCGCGATG
AGCGGCCTCAACGGCGGCCGGCTCAATATCGCAGCATGCTCGCTGGGTGGCGCGCAGGCCGCCTTTGACAAAGCGGGCGC
CTACGTTCGCGACCGACAGGCCTTCGGCGGATCGCTGCTCGACGAGCCCACCGTGCGGTTTACCCTGGCCGACATGGCTA
CCGGGCTGCAGACGTCGCGAATGTTGTTGTGGCGGGCCGCAAGTGCGCTCGATGACGACGACGCCGACAAGGTCGAGCTG
TGTGCGATGGCCAAGCGCTACGTCACCGACACCTGCTTTGAGGTCGCCGACCAGGCCCTGCAGCTGCACGGCGGCTATGG
CTATCTGCGCGAGTATGGTCTGGAGAAGATCGTCCGCGACCTGCGGGTGCATCGCATCCTGGAAGGGACCAACGAGATCA
TGCGGCTGGTCATCGGTCGGGCCGAGGCCGCGCGGTTCCGCGCCACCGTTTAG

Upstream 100 bases:

>100_bases
AATCCAGTTCTACACCAAGGTCAAGACCGTCACGTCGCGATGGCCGTCAGGCATCAAGGACGGTGCCGAATTCGTCATCC
CCACAATGAGTTAGCGTGTC

Downstream 100 bases:

>100_bases
AGAGGCTCAGATGACGACCATCGCCTTCCTAGGTTTGGGCAACATGGGTGCGCCGATGTCGGCGAATCTGGTTGGTGCGG
GCCACGTCGTGCGTGGATTC

Product: acyl-CoA dehydrogenase FadE9

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGVRIFEQLAIADP
VTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFIS
GAAASDVYVVMARTGAEGPRGVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVEL
CAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV

Sequences:

>Translated_390_residues
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGVRIFEQLAIADP
VTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFIS
GAAASDVYVVMARTGAEGPRGVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVEL
CAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV
>Mature_390_residues
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGVRIFEQLAIADP
VTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFIS
GAAASDVYVVMARTGAEGPRGVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVEL
CAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=52.3809523809524, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=36.8700265251989, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4557231, Length=390, Percent_Identity=32.3076923076923, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI187960098, Length=390, Percent_Identity=32.3076923076923, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI4501859, Length=386, Percent_Identity=33.419689119171, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI76496475, Length=360, Percent_Identity=33.6111111111111, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI4557235, Length=360, Percent_Identity=33.6111111111111, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=32.7225130890052, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI226958412, Length=390, Percent_Identity=31.5384615384615, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=31.7142857142857, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=29.6610169491525, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4503943, Length=383, Percent_Identity=30.8093994778068, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI7669494, Length=354, Percent_Identity=30.7909604519774, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=27.3648648648649, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=27.3648648648649, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI38505218, Length=306, Percent_Identity=26.797385620915, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI87081958, Length=353, Percent_Identity=31.728045325779, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786223, Length=390, Percent_Identity=27.6923076923077, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87082384, Length=275, Percent_Identity=29.4545454545455, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081702, Length=340, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=48.5488126649077, Blast_Score=373, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17534899, Length=389, Percent_Identity=35.2185089974293, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17569725, Length=385, Percent_Identity=33.7662337662338, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=32.1052631578947, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17538396, Length=389, Percent_Identity=33.6760925449871, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=31.6622691292876, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=33.6134453781513, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=29.639175257732, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=30.7894736842105, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=292, Percent_Identity=32.8767123287671, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17551932, Length=378, Percent_Identity=28.5714285714286, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=389, Percent_Identity=28.2776349614396, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=37.0689655172414, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=32.1428571428571, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=32.404181184669, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=27.3469387755102, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=265, Percent_Identity=29.0566037735849, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=313, Percent_Identity=29.7124600638978, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=313, Percent_Identity=29.7124600638978, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24660351, Length=393, Percent_Identity=34.6055979643766, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=34.5646437994723, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=36.6754617414248, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=35.0132625994695, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=34.4117647058824, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21355753, Length=393, Percent_Identity=32.5699745547074, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=28.5714285714286, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41452; Mature: 41452

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGG
CEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCC
SGLRRLDGVRIFEQLAIADPVTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIAS
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAEGPR
HHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
GVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEE
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSR
ECCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHCCHHHHH
MLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LRVHRILEGTNEIMRLVIGRAEAARFRATV
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGG
CEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCC
SGLRRLDGVRIFEQLAIADPVTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIAS
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAEGPR
HHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
GVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEE
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSR
ECCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHCCHHHHH
MLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LRVHRILEGTNEIMRLVIGRAEAARFRATV
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]