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The map label for this gene is tcmO [H]

Identifier: 148660336

GI number: 148660336

Start: 659631

End: 660650

Strand: Direct

Name: tcmO [H]

Synonym: MRA_0574

Alternate gene names: 148660336

Gene position: 659631-660650 (Clockwise)

Preceding gene: 148660332

Following gene: 148660337

Centisome position: 14.92

GC content: 63.73

Gene sequence:

>1020_bases
GTGGAGTTGAGCCCGGATCGGATCATGGCGATCGGCGGCGGGTACGGCCCGTCTAAGGTACTGCTTACCGCGGTCGGGCT
TGGGCTGTTCACCGAACTTGGCGATGAGGCCATGACCGCCGAGGCCATTGCCGACCGCCTCGGGTTGCTAAAGCGACCGG
CGATTGACTTCCTCGACGCCTTGGTCTCGCTGGACTTGCTGGCGCGAGACGGCGACGGACCCGGGTCCCACTACCGCAAT
ACACCGGAGACAGCGCACTTTCTGGACGAGGCCCGTCCCACCTACGCGGGCGGCCTGCTGAAGATCTGGAACGAACGCAA
CTACCGCTTCTGGGCGGATTTGACCGAGGCGCTCAAGACCGGGAAGGCACAAAGCGAGGTCAAGCAAACCGGGCGGCCCT
TCTTCGAGGCGCTCTATGCAGATCCTCGGCGGCTCGAGGCGTTCATGGCGGCTATGGACGCGGCGTCGCGACGCAACATC
GAGCTCCTCGCGAAACGCTTTCCGTTCGAGCGCTACCGGCGTCTCTGTGACGTGGGCTGCGCGGACGGTCTGTTGTCACG
AATCGTCGCGGCGGCTCACCCGCACTTGCAGTGCGTCAGCTTCGACTTGCCCGCGGTGACCGAGATCGCTCGACGCAAGC
TGACAGCCGAGGGTTTGGGTGAGCGGGTGCAGGCGTGCGCCGGTGACTTTTTGGCCGACCCTCTGCCGGCGGCCGATGTC
ATCACGATGGGCCAGATTCTGCACGACTGGAACCTCGACCGTAAACAGCAGTTGGTCGCTAAGGCCTACGAGGCCCTGTC
CAAGGAGGGGGCTTTCATTGTGATCGAGACATTGATCGACGACGCGCGACGCGAAAACACAACCGGCCTGATGATGTCAC
TGAACATGCTTATCGAGTTCGGTGACGCGTTCGACTACTCCGCCGCCGACTTCCGGGGGTGGTGTGGCGAGGCGGGATTC
CGTTCGTTCGAGGTGATCCCGCTTGCCGGCGGCTCCAGCGCGGCGGTGGCCTATAAATAG

Upstream 100 bases:

>100_bases
CCGGGCATGGCCACGCCCGCGCGTTGGTGCCCCAACGTCGCCTACGGTCGGTAGACAGCGGCGCGACACCCGCACTCCAA
CAATTTCGGGAGGTCAAGTG

Downstream 100 bases:

>100_bases
TGGGCAATGACATGGTGGGTGGCCGACCAACGTGAACTGAGGACGGCAAATCGGCCTCAGTTCACGCTCGGCGCTTTGAG
CAACAAATTGAACACATAGA

Product: tetracenpmycin polyketide synthesis 8-o-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRN
TPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNI
ELLAKRFPFERYRRLCDVGCADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSAADFRGWCGEAGF
RSFEVIPLAGGSSAAVAYK

Sequences:

>Translated_339_residues
MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRN
TPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNI
ELLAKRFPFERYRRLCDVGCADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSAADFRGWCGEAGF
RSFEVIPLAGGSSAAVAYK
>Mature_339_residues
MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRN
TPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNI
ELLAKRFPFERYRRLCDVGCADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSAADFRGWCGEAGF
RSFEVIPLAGGSSAAVAYK

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI291045183, Length=340, Percent_Identity=30, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI291045181, Length=340, Percent_Identity=30, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI117553627, Length=340, Percent_Identity=30, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI283549144, Length=346, Percent_Identity=26.5895953757225, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI157168360, Length=346, Percent_Identity=26.5895953757225, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI283549146, Length=317, Percent_Identity=25.5520504731861, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016461
- InterPro:   IPR001077
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00891 Methyltransf_2 [H]

EC number: NA

Molecular weight: Translated: 37144; Mature: 37144

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHH
LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHEECCCCCCHHHHHHHHHHC
GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC
CCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCH
ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
HHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHH
GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK
CCCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCEECC
>Mature Secondary Structure
MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHH
LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHEECCCCCCHHHHHHHHHHC
GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC
CCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCH
ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
HHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHH
GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK
CCCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1548230 [H]