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The map label for this gene is grcC1 [H]

Identifier: 148660331

GI number: 148660331

Start: 654081

End: 655088

Strand: Direct

Name: grcC1 [H]

Synonym: MRA_0569

Alternate gene names: 148660331

Gene position: 654081-655088 (Clockwise)

Preceding gene: 148660327

Following gene: 148660332

Centisome position: 14.8

GC content: 67.76

Gene sequence:

>1008_bases
GTGAGGACTCCGGCGACGGTGGTGGCAGGCGTTGACCTGGGCGACGCTGTCTTTGCCGCGGCCGTGCGTGCTGGTGTCGC
GCGAGTCGAGCAACTCATGGACACCGAGCTGCGCCAGGCCGACGAGGTGATGAGCGATTCGCTGCTGCACTTGTTCAATG
CCGGCGGCAAGCGGTTCCGTCCACTGTTCACCGTGCTGTCGGCGCAGATCGGGCCGCAGCCGGATGCCGCAGCGGTGACA
GTCGCCGGGGCGGTGATCGAGATGATCCACCTGGCGACCCTCTACCACGATGACGTGATGGACGAGGCCCAGGTCCGCCG
CGGCGCGCCCAGCGCCAACGCGCAATGGGGTAACAACGTCGCGATCCTGGCTGGCGACTACCTACTGGCCACCGCATCGC
GGCTGGTGGCGAGGTTGGGACCGGAGGCGGTGCGGATCATCGCCGACACCTTCGCCCAGTTGGTGACCGGGCAGATGCGT
GAGACGCGCGGCACGTCGGAGAACGTGGACTCCATCGAGCAGTACCTGAAGGTGGTCCAGGAGAAGACCGGCAGTCTAAT
CGGGGCGGCCGGCCGGCTGGGTGGGATGTTCTCCGGTGCCACCGACGAACAGGTCGAACGGCTGAGCCGCCTCGGCGGCG
TGGTGGGCACCGCGTTTCAGATCGCCGACGACATTATCGACATCGACAGCGAGTCTGACGAGTCGGGCAAGCTGCCCGGT
ACCGATGTGCGCGAAGGAGTACACACCCTGCCGATGCTCTACGCGTTACGGGAATCAGGGCCCGATTGCGCTCGGTTGCG
CGCACTGCTGAACGGACCGGTCGACGACGACGCCGAGGTGCGCGAGGCGCTGACATTGTTGCGGGCGTCGCCGGGCATGG
CCCGGGCCAAAGACGTCCTGGCGCAGTACGCGGCTCAGGCACGTCACGAGCTGGCCTTACTGCCCGACGTCCCGGGACGG
CGTGCCCTGGCGGCGCTGGTCGACTACACCGTGAGCCGGCACGGCTAG

Upstream 100 bases:

>100_bases
CCGCGCGGGCAGCCCAGGCGGCCGCAGCTGACCCGGCCGGTCCGGCGCCCACGACCACCACGTCGGCACTGTCATCCACG
CTCACCAGTATGTTGGTCGA

Downstream 100 bases:

>100_bases
GTTGCCCGGCCAGGCTCGATTGCGGAACCAGCGGATACCCCTCAGGCGTTGAACCAGCAGTAATCTCCCAAGTTGAGGTG
TTCTAGGAGGACACGCACTG

Product: putative polyprenyl-diphosphate synthase GrcC1

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFRPLFTVLSAQIGPQPDAAAVT
VAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNVAILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMR
ETRGTSENVDSIEQYLKVVQEKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPG
TDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVLAQYAAQARHELALLPDVPGR
RALAALVDYTVSRHG

Sequences:

>Translated_335_residues
MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFRPLFTVLSAQIGPQPDAAAVT
VAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNVAILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMR
ETRGTSENVDSIEQYLKVVQEKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPG
TDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVLAQYAAQARHELALLPDVPGR
RALAALVDYTVSRHG
>Mature_335_residues
MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFRPLFTVLSAQIGPQPDAAAVT
VAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNVAILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMR
ETRGTSENVDSIEQYLKVVQEKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPG
TDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVLAQYAAQARHELALLPDVPGR
RALAALVDYTVSRHG

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=316, Percent_Identity=31.9620253164557, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI4758430, Length=229, Percent_Identity=26.2008733624454, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI83700220, Length=229, Percent_Identity=26.2008733624454, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789578, Length=295, Percent_Identity=32.8813559322034, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786623, Length=222, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17505681, Length=239, Percent_Identity=33.4728033472803, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319475, Length=295, Percent_Identity=28.4745762711864, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6325188, Length=311, Percent_Identity=23.1511254019293, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651612, Length=292, Percent_Identity=28.7671232876712, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI281365769, Length=299, Percent_Identity=28.0936454849498, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24660002, Length=299, Percent_Identity=28.0936454849498, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 35561; Mature: 35561

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFR
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
PLFTVLSAQIGPQPDAAAVTVAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
AILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMRETRGTSENVDSIEQYLKVVQ
EEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPG
HHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
TDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVL
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
AQYAAQARHELALLPDVPGRRALAALVDYTVSRHG
HHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTPATVVAGVDLGDAVFAAAVRAGVARVEQLMDTELRQADEVMSDSLLHLFNAGGKRFR
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
PLFTVLSAQIGPQPDAAAVTVAGAVIEMIHLATLYHDDVMDEAQVRRGAPSANAQWGNNV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
AILAGDYLLATASRLVARLGPEAVRIIADTFAQLVTGQMRETRGTSENVDSIEQYLKVVQ
EEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EKTGSLIGAAGRLGGMFSGATDEQVERLSRLGGVVGTAFQIADDIIDIDSESDESGKLPG
HHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
TDVREGVHTLPMLYALRESGPDCARLRALLNGPVDDDAEVREALTLLRASPGMARAKDVL
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
AQYAAQARHELALLPDVPGRRALAALVDYTVSRHG
HHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]