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The map label for this gene is galE3 [C]

Identifier: 148660305

GI number: 148660305

Start: 628558

End: 629598

Strand: Direct

Name: galE3 [C]

Synonym: MRA_0543

Alternate gene names: 148660305

Gene position: 628558-629598 (Clockwise)

Preceding gene: 148660304

Following gene: 148660307

Centisome position: 14.22

GC content: 70.32

Gene sequence:

>1041_bases
ATGAGGGTGCTGCTGACCGGCGCGGCCGGCTTCATCGGGTCGCGCGTGGATGCGGCGTTACGGGCTGCGGGTCACGACGT
GGTGGGCGTCGACGCGCTGCTGCCCGCCGCGCACGGGCCAAACCCGGTGCTGCCACCGGGCTGCCAGCGGGTCGACGTGC
GCGACGCCAGCGCGCTGGCCCCGTTGTTGGCCGGTGTCGATCTGGTGTGTCACCAGGCCGCCATGGTGGGTGCCGGCGTC
AACGCCGCCGACGCACCCGCCTATGGCGGCCACAACGATTTCGCCACCACGGTGCTGCTGGCGCAGATGTTCGCCGCCGG
GGTCCGCCGTTTGGTGCTGGCGTCGTCGATGGTGGTTTACGGGCAGGGGCGCTATGACTGTCCCCAGCATGGACCGGTCG
ACCCGCTGCCGCGGCGGCGAGCCGACCTGGACAATGGGGTCTTCGAGCACCGTTGCCCGGGGTGCGGCGAGCCAGTCATC
TGGCAATTGGTCGACGAGGATGCCCCGTTGCGCCCGCGCAGCCTGTACGCGGCCAGCAAGACCGCGCAGGAGCACTACGC
GCTGGCGTGGTCGGAAGCGAGTGGCGGTTCGGTGGTGGCGTTGCGCTACCACAACGTCTACGGCCCCGGCATGCCGCGCG
ACACCCCCTACTCCGGAGTGGCCGCGATCTTCCGCTCGGCGGTTGAAAAAGGCAAGCCACCAAAGGTTTTCGAAGACGGC
GGCCAGATGCGGGACTTCGTGCACGTGGACGACGTGGCCGCGGCGAACCTCGCCGCGGTGCATCTGGGTGAAGCGGACCG
CGACGGGTTTACCGCGGTCAACGTCTGTTCCGGGCGCCCCATCTCGATCCTTCAGGTGGCAACCGCGATATGCGACGCCC
GCGGTGGCTCGATGTCCCCGGCCATCACCGGGCACTACCGCAGCGGCGACGTGCGCCACATTGTCGCCGATCCCGCGCGG
GCCGCCCGCGTGCTCGGGTTCCGCGCGGCCGTCGATCCAGGCGAAGGACTGCGTGAGTTCGCGTTCGCGCCGCTTCGCTG
A

Upstream 100 bases:

>100_bases
TCAAAAGGCTGGTGCGGGCCGCCATCGATCGGGTCGCCGACGAGCGCACGTGCACGCACTGTCAACACCACGCCGGTGTT
CCGTTGCCGTTCGAGCTGCC

Downstream 100 bases:

>100_bases
CCGCTCGAGCTACGACGAGTGGTCCGGCGGCCGGTAGATCTTCGGCCGCACTGGGTGCGTCGACCCAGCTGACCTGAAAA
TCCGGGGGGATCCAGCAGGC

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAMVGAGV
NAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVI
WQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIVADPAR
AARVLGFRAAVDPGEGLREFAFAPLR

Sequences:

>Translated_346_residues
MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAMVGAGV
NAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVI
WQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIVADPAR
AARVLGFRAAVDPGEGLREFAFAPLR
>Mature_346_residues
MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAMVGAGV
NAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVI
WQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIVADPAR
AARVLGFRAAVDPGEGLREFAFAPLR

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=359, Percent_Identity=28.9693593314763, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI56118217, Length=359, Percent_Identity=28.9693593314763, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI189083684, Length=359, Percent_Identity=28.9693593314763, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36219; Mature: 36219

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
CEEEEECCCHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCCCCEECCCCHHHHH
PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEE
GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
ECCCCCCCCCCCCCCCCCHHCCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHH
TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
HHHHHEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCC
GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
CCHHHEEECCHHHHHCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
CEEECCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
CEEEEECCCHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCCCCEECCCCHHHHH
PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEE
GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
ECCCCCCCCCCCCCCCCCHHCCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHH
TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
HHHHHEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCC
GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
CCHHHEEECCHHHHHCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
CEEECCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]