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The map label for this gene is deoC

Identifier: 148660245

GI number: 148660245

Start: 568532

End: 569206

Strand: Direct

Name: deoC

Synonym: MRA_0485

Alternate gene names: 148660245

Gene position: 568532-569206 (Clockwise)

Preceding gene: 148660244

Following gene: 148660249

Centisome position: 12.86

GC content: 69.63

Gene sequence:

>675_bases
GTGCTCGGCCAACCGACTCGGGCGCAGTTGGCCGCGCTGGTAGACCACACCCTGCTCAAGCCTGAGACCACCCGTGCCGA
TGTGGCCGCGCTGGTCGCCGAAGCCGCCGAACTCGGCGTCTACGCGGTCTGCGTGTCGCCGTCGATGGTGCCAGTTGCGG
TCCAAGCCGGTGGTGTGCGGGTTGCGGCGGTGACGGGCTTCCCGTCGGGCAAGCACGTGTCCTCGGTCAAGGCGCATGAG
GCGGCTGCGGCCCTGGCATCCGGCGCCAGTGAGATCGACATGGTCATCGACATCGGGGCTGCGCTGTGCGGTGACATCGA
CGCAGTGCGCTCCGACATCGAGGCGGTGCGTGCCGCTGCGGCCGGGGCTGTGCTCAAGGTGATCGTGGAGTCGGCGGTGC
TGTTGGGACAGTCAAACGCGCACACGTTGGTGGATGCGTGTCGTGCCGCCGAGGATGCCGGTGCCGACTTCGTCAAAACC
TCGACTGGGTGTCATCCGGCCGGCGGGGCCACGGTGCGTGCCGTCGAGCTGATGGCCGAGACGGTCGGCCCTCGGCTAGG
GGTCAAAGCCAGCGGTGGGATCCGCACCGCCGCCGACGCGGTCGCGATGCTCAACGCCGGTGCCACCAGGTTGGGCCTGT
CCGGCACCCGGGCGGTGCTCGATGGGCTCAGCTGA

Upstream 100 bases:

>100_bases
GCAAACCCAGCTGGAACCTCGAGCCGTGGCGGCCGGTCGTCGACGACTCGGAGATGTTGGCTTCCGGCTGCAATCCGGGC
AGCCCTGAAGAGTCGTTTTA

Downstream 100 bases:

>100_bases
CAGCTGAGCGCGCGGGTGGCGGCGTCAAATGTGCGAGAAGCAGGGATTCTGGATGCCGGTGGGGATAGCCGCGTCGCGAG
TTGAGAACCGGCTCACCACG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHE
AAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKT
STGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS

Sequences:

>Translated_224_residues
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHE
AAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKT
STGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
>Mature_224_residues
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHE
AAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKT
STGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=183, Percent_Identity=34.9726775956284, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1790841, Length=208, Percent_Identity=34.1346153846154, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17533015, Length=216, Percent_Identity=30.0925925925926, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922098, Length=196, Percent_Identity=33.1632653061224, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_MYCBO (P63930)

Other databases:

- EMBL:   BX248335
- RefSeq:   NP_854151.1
- ProteinModelPortal:   P63930
- SMR:   P63930
- EnsemblBacteria:   EBMYCT00000018050
- GeneID:   1091527
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0488
- GeneTree:   EBGT00050000017372
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   PRK00507
- BioCyc:   MBOV233413:MB0488-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22068; Mature: 22068

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: ACT_SITE 159-159 ACT_SITE 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVR
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCEE
VAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAA
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHH
TVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
HHCCCCCCCCCCCCHHHHHHHHHHHCCCHHCCCCHHHHHHCCCC
>Mature Secondary Structure
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVR
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCEE
VAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAA
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHH
TVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
HHCCCCCCCCCCCCHHHHHHHHHHHCCCHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972