Click here to switch to the map view.

The map label for this gene is ppe10

Identifier: 148660207

GI number: 148660207

Start: 532061

End: 533524

Strand: Reverse

Name: ppe10

Synonym: MRA_0447

Alternate gene names: 148660207

Gene position: 533524-532061 (Counterclockwise)

Preceding gene: 148660209

Following gene: 148660206

Centisome position: 12.07

GC content: 66.12

Gene sequence:

>1464_bases
GTGACAAGCCCGCATTTTGCGTGGTTGCCGCCAGAGATCAATTCGGCACTGATGTTTGCCGGTCCCGGGTCGGGACCGCT
AATTGCTGCGGCCACCGCCTGGGGCGAGCTGGCCGAAGAATTGCTCGCGTCAATAGCGTCGCTTGGCTCCGTCACATCCG
AACTGACTAGTGGCGCCTGGCTGGGTCCGTCCGCGGCGGCGATGATGGCCGTCGCAACCCAGTACCTAGCCTGGCTCAGC
ACGGCGGCAGCGCAGGCGGAACAAGCGGCCGCACAGGCCATGGCAATAGCGACCGCGTTCGAGGCGGCGCTGGCGGCCAC
CGTGCAGCCGGCAGTGGTAGCGGCCAATCGTGGCCTGATGCAGCTGCTGGCAGCTACGAACTGGTTTGGGCAGAATGCTC
CGGCGCTCATGGACGTCGAGGCGGCATACGAGCAAATGTGGGCATTGGACGTGGCGGCGATGGCTGGTTACCACTTCGAT
GCGTCTGCGGCCGTCGCACAACTGGCGCCCTGGCAGCAGGTCTTGCGGAACCTCGGCATCGACATCGGCAAGAACGGCCA
GATCAATCTGGGCTTCGGCAACACCGGCAGCGGCAACATCGGCAACAACAACATCGGCAACAACAACATCGGCAGCGGCA
ACACCGGCACCGGCAACATCGGCAGCGGCAACACCGGCAGCGGCAACCTGGGCCTCGGCAACCTCGGCGACGGGAATATC
GGCTTCGGCAACACCGGTAGCGGGAATATCGGGTTCGGGATCACCGGTGATCACCAGATGGGTTTCGGCGGCTTCAACTC
GGGTAGCGGCAACATCGGCTTCGGGAACTCGGGCACCGGCAACGTCGGCTTATTCAACTCCGGCAGCGGAAACATCGGCA
TCGGGAATTCGGGCTCCCTGAACAGCGGCATCGGGACCTCGGGGACAATCAACGCGGGCCTCGGCAGCGCAGGCAGCCTC
AACACCAGCTTCTGGAACGCGGGGATGCAAAACGCCGCCTTAGGAAGCGCGGCTGGCTCGGAGGCGGCCTTGGTCAGCTC
CGCCGGCTACGCCACCGGCGGCATGAGCACGGCGGCTTTGAGTTCGGGCATCCTCGCCTCCGCCCTCGGATCAACGGGCG
GTCTCCAACACGGCCTGGCGAACGTCCTCAACTCGGGCCTGACCAACACGCCCGTCGCCGCCCCGGCCAGTGCTCCTGTT
GGCGGCCTGGACTCAGGCAACCCGAACCCCGGTAGCGGCAGTGCCGCGGCTGGCTCGGGCGCAAACCCGGGCCTTAGAAG
CCCTGGCACCAGCTACCCGAGCTTCGTCAACTCGGGCAGCAACGACTCGGGCTTGCGGAATACCGCCGTGCGTGAGCCGA
GTACCCCCGGCTCCGGCATCCCCAAGTCGAACTTCTACCCGAGCCCCGACCGCGAATCCGCCTACGCCAGCCCGCGGATC
GGGCAGCCGGTCGGTTCGGAGTAA

Upstream 100 bases:

>100_bases
TGGCGGTTCCTAGGGGCGCTCCAAAGATGACCCCAAAGATGAGTGGTATTGAAGTGCCGATACCGCCACGGCAACGGTCG
CTGACAGTTAAGTTGGATCA

Downstream 100 bases:

>100_bases
CACATCGGGCGCCTATCCTCGAATCCGTGGGTGCCAAAAAGGTAGACCTCAAACGGCTGGCCGCCGCCTTGCCCGACTAC
CCGTTCGCTTACCTGATCAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTSPHFAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAWLGPSAAAMMAVATQYLAWLS
TAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLMQLLAATNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFD
ASAAVAQLAPWQQVLRNLGIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNI
GFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSL
NTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPV
GGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASPRI
GQPVGSE

Sequences:

>Translated_487_residues
MTSPHFAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAWLGPSAAAMMAVATQYLAWLS
TAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLMQLLAATNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFD
ASAAVAQLAPWQQVLRNLGIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNI
GFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSL
NTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPV
GGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASPRI
GQPVGSE
>Mature_486_residues
TSPHFAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAWLGPSAAAMMAVATQYLAWLST
AAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLMQLLAATNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFDA
SAAVAQLAPWQQVLRNLGIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNIG
FGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLN
TSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVG
GLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASPRIG
QPVGSE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE10_MYCTU (P42611)

Other databases:

- EMBL:   M15467
- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   C70830
- RefSeq:   NP_334867.1
- RefSeq:   YP_177726.1
- ProteinModelPortal:   P42611
- SMR:   P42611
- EnsemblBacteria:   EBMYCT00000001793
- EnsemblBacteria:   EBMYCT00000071692
- GeneID:   886340
- GeneID:   923787
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0458
- KEGG:   mtu:Rv0442c
- TIGR:   MT0458
- TubercuList:   Rv0442c
- GeneTree:   EBGT00050000014886
- HOGENOM:   HBG572308
- OMA:   EAPANAG
- ProtClustDB:   CLSK799710
- InterPro:   IPR002989
- InterPro:   IPR000030

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE

EC number: NA

Molecular weight: Translated: 47247; Mature: 47116

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPHFAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAW
CCCCCCEECCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LGPSAAAMMAVATQYLAWLSTAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QLLAATNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFDASAAVAQLAPWQQVLRNLGI
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
DIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNI
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSL
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
NSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAAL
CCCCCCCCEEECCCCCCCCCCHHHHHCCCCHHHCCCCCCCCCEEEECCCCCCCCCHHHHH
SSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAGSG
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASPRI
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQPVGSE
CCCCCCC
>Mature Secondary Structure 
TSPHFAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAW
CCCCCEECCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LGPSAAAMMAVATQYLAWLSTAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QLLAATNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFDASAAVAQLAPWQQVLRNLGI
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
DIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNI
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSL
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
NSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAAL
CCCCCCCCEEECCCCCCCCCCHHHHHCCCCHHHCCCCCCCCCEEEECCCCCCCCCHHHHH
SSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAGSG
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASPRI
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQPVGSE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3029018; 9634230; 12218036