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The map label for this gene is cobU [H]

Identifier: 148660019

GI number: 148660019

Start: 307187

End: 307711

Strand: Reverse

Name: cobU [H]

Synonym: MRA_0263

Alternate gene names: 148660019

Gene position: 307711-307187 (Counterclockwise)

Preceding gene: 148660020

Following gene: 148660016

Centisome position: 6.96

GC content: 67.24

Gene sequence:

>525_bases
GTGCGGATACTGGTCACTGGCGGCGTCCGCTCGGGAAAGTCCACGCACGCCGAAGCGTTGTTGGGCGATGCGGCCGACGT
CGTCTACGTCGCGCCTGGCCGCCCGGCCGCTGGCAGCGATCCCGATTGGGACGCCCGGGTCGCACTGCATCGCGCTCGCC
GCCCACCGACCTGGCTAACGGTGGAAACGGCCGACGTCGCGACGGCTTTGTCCGAGGCACGAAGTCCCGTGCTCGTGGAC
TGCTTGGGCACCTGGCTGACGGCCATCATGGATGGCGAGGCGTTGTGGTCTGCTGCGACCGCGGACGTCTACGCCGTCCT
CGAGGCACGGCTCGACGGGTTGTGCGCCGCGCTGACCGGATTGCCCACTGCGATCGTGGTGACGAACGAGGTCGGCCTCG
GGGTGGTGCCATCCCATTCTTCGGGCGTGCTGTTTCGCGATCTACTGGGCACAATCAACCGACGCGTGGCAGCCGTCTGC
GATGAGGTACATCTGGTCATCGCCGGACGTGTGCTCAAGCTGTGA

Upstream 100 bases:

>100_bases
CGTCGATGCGCTGCTCAACCTGGCCCGCCATGGTTGCCCGCCGACCTTGCCCTTTCTCGCTCCGGGCGCGCCATGAGGCC
GCCCCACCTACGATGACCCG

Downstream 100 bases:

>100_bases
GGTTCGCGGGGTGAGCTAGACCGCTACCCGCGCGACCTGAATGCGGCCTTCGGGTGTGACGCGCGCCGGATACACCGGCA
CCGAAACGCGCGGATCGTCG

Product: cobinamide kinase/cobinamide phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVETADVATALSEARSPVLVD
CLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVC
DEVHLVIAGRVLKL

Sequences:

>Translated_174_residues
MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVETADVATALSEARSPVLVD
CLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVC
DEVHLVIAGRVLKL
>Mature_174_residues
MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVETADVATALSEARSPVLVD
CLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVC
DEVHLVIAGRVLKL

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=191, Percent_Identity=37.17277486911, Blast_Score=103, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18142; Mature: 18142

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT
CEEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEEE
VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG
EEHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL
CCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCEEECC
>Mature Secondary Structure
MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT
CEEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEEE
VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG
EEHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL
CCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]