Click here to switch to the map view.

The map label for this gene is ppe28 [H]

Identifier: 148659916

GI number: 148659916

Start: 180679

End: 182256

Strand: Reverse

Name: ppe28 [H]

Synonym: MRA_0159

Alternate gene names: 148659916

Gene position: 182256-180679 (Counterclockwise)

Preceding gene: 148659917

Following gene: 148659915

Centisome position: 4.12

GC content: 63.24

Gene sequence:

>1578_bases
ATGAGGTGTCGGCCGCCATCGCGAAACCGTTCGGCGCATACGGCCAGGAATACCAGGCCGTGCTCGCTCAAGTCGAGGCG
TTTCACAGTTAGGTTCCACCAGACGTTGGCCGCCGCGGCGAACAGCTACGCAGATGCCGAGGCCGCCATCGCCAGCACCC
GGCAAAATCAGCTGGCTGTGCCCGCCGCCGCACCAACCCCCGCGGCGGCCGCGATGATTCCGCCATTCCCGGCGAACTTG
ACCACCTTGTTCTTTGGGCCCACCGGAATTCCACTACCACCGCCGTCTATGTTGACGCCGCCAATACGCTGTAGGTCCGT
TCGGCGGGCGCTACAAGCCGTCTTCACACCCGAAGAGTTGTACCCACTCACCGGTGTCAGAAGTTTGGTCCTCAACACGT
CAGTGGAAGAGGGCTTGACCATCTTGCACGACGCGATCATGGTAGAGCTCGCGACCACCGGAAACGCGGTCACCGTTTTC
GGCTGGTCGCAAAGCGCCATAATCGCGTCGCTGGAGATGCAGAGGTTCACGGCGATGGGCGGGGCCGCACCTTCGGCGAG
CGACCTCAATTTCGTGCTTGTCGGCAATGAAATGAACCCCAATGGCGGTATGCTCGCGCGGTTCCCGGATCTGACGCTTC
CGACTCTGGACCTGACGTTCTATGGCGCAACGCCCTCGGACACGATCTATCCGACGGCCATCTACACGCTCGAGTACGAC
GGGTTCGCCGACTTCTCGCGATACCCGCTCAACTTCATTTCCGACCTCAACGCGGTTGCAGGCATCACATTCGTACACAC
CAAGTATTTGGACCTCACGCCCGCGCAGGTCGAGGGCGCTACTAAATTACCGACGTCGCCGGGCTATACGGGGGTCACCG
ACTACTACATCATCCGCACCGAGAATCGGCCGCTGCTGCAACCGCTGCGGGCGGTGCCGGTCATCGGAGATCCGCTGGCC
GACCTGATCCAGCCGAACCTGAAGGTGATCGTCAACCTGGGCTACGGCGACCCGAACTACGGCTACTCGACGAGCTACGC
CGATGTGCGAACGCCGTTCGGGCTGTGGCCGAACGTGCCGCCTCAGGTCATCGCCGATGCCCTGGCCGCCGGAACACAAG
AAGGCATCCTTGACTTCACGGCCGACCTGCAGGCGCTGTCCGCGCAACCGCTCACGCTCCCGCAGATCCAGCTGCCGCAA
CCCGCCGATCTGGTGGCCGCGGTGGCCGCCGCACCGACGCCGGCCGAGGTGGTGAACACGCTCGCCAGGATCATCTCAAC
CAACTACGCCGTCCTGCTGCCCACCGTGGACATCGCCCTCGCCCTGGTCACCACCCTGCCGCTGTACACCACCCAACTGT
TCGTCAGGCAACTCGCTGCGGGCAATCTGATCAACGCGATCGGCTATCCCCTGGCGGCCACCGTAGGTTTAGGCACGATC
GATAGCGGGCGGCGTGGAATTGCTCACCCTCCTCGCGGCGGCCTCGGACACCGTTCGAAACATCGAGGGCCTCGTCACCT
AACGGATTCCCGACGGCATCGACGTCCACCGACTACCGTTTACCGACCTCGCCAATGA

Upstream 100 bases:

>100_bases
GCGGCGGCCGCCGCCGAGGTGGCAGGAATCGGTTCGGCCGTGAGTACGGCCGGCGCGGCCGCGGCAGGCCCGACGTGTGC
ACTGGCCGCGGCGGCCGGCG

Downstream 100 bases:

>100_bases
CGAGGCAGCATGGCCCCATTTGGGTTCACTCCAAAGGCCAGACACAACCGCGGAGTCGCTTTACGCTCAACGTATCGGCT
CGACGGGTGGGTTATGGGCC

Product: PE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYADAEAAIASTRQNQLAVPAAAPTPAAAAMIPPFPANL
TTLFFGPTGIPLPPPSMLTPPIRCRSVRRALQAVFTPEELYPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVF
GWSQSAIIASLEMQRFTAMGGAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDLTFYGATPSDTIYPTAIYTLEYD
GFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQVEGATKLPTSPGYTGVTDYYIIRTENRPLLQPLRAVPVIGDPLA
DLIQPNLKVIVNLGYGDPNYGYSTSYADVRTPFGLWPNVPPQVIADALAAGTQEGILDFTADLQALSAQPLTLPQIQLPQ
PADLVAAVAAAPTPAEVVNTLARIISTNYAVLLPTVDIALALVTTLPLYTTQLFVRQLAAGNLINAIGYPLAATVGLGTI
DSGRRGIAHPPRGGLGHRSKHRGPRHLTDSRRHRRPPTTVYRPRQ

Sequences:

>Translated_525_residues
MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYADAEAAIASTRQNQLAVPAAAPTPAAAAMIPPFPANL
TTLFFGPTGIPLPPPSMLTPPIRCRSVRRALQAVFTPEELYPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVF
GWSQSAIIASLEMQRFTAMGGAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDLTFYGATPSDTIYPTAIYTLEYD
GFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQVEGATKLPTSPGYTGVTDYYIIRTENRPLLQPLRAVPVIGDPLA
DLIQPNLKVIVNLGYGDPNYGYSTSYADVRTPFGLWPNVPPQVIADALAAGTQEGILDFTADLQALSAQPLTLPQIQLPQ
PADLVAAVAAAPTPAEVVNTLARIISTNYAVLLPTVDIALALVTTLPLYTTQLFVRQLAAGNLINAIGYPLAATVGLGTI
DSGRRGIAHPPRGGLGHRSKHRGPRHLTDSRRHRRPPTTVYRPRQ
>Mature_525_residues
MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYADAEAAIASTRQNQLAVPAAAPTPAAAAMIPPFPANL
TTLFFGPTGIPLPPPSMLTPPIRCRSVRRALQAVFTPEELYPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVF
GWSQSAIIASLEMQRFTAMGGAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDLTFYGATPSDTIYPTAIYTLEYD
GFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQVEGATKLPTSPGYTGVTDYYIIRTENRPLLQPLRAVPVIGDPLA
DLIQPNLKVIVNLGYGDPNYGYSTSYADVRTPFGLWPNVPPQVIADALAAGTQEGILDFTADLQALSAQPLTLPQIQLPQ
PADLVAAVAAAPTPAEVVNTLARIISTNYAVLLPTVDIALALVTTLPLYTTQLFVRQLAAGNLINAIGYPLAATVGLGTI
DSGRRGIAHPPRGGLGHRSKHRGPRHLTDSRRHRRPPTTVYRPRQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 56354; Mature: 56354

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYADAEAAIASTRQNQLAV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCCCEEC
PAAAPTPAAAAMIPPFPANLTTLFFGPTGIPLPPPSMLTPPIRCRSVRRALQAVFTPEEL
CCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHH
YPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVFGWSQSAIIASLEMQRFTAMG
CCHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHC
GAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDLTFYGATPSDTIYPTAIYTLEYD
CCCCCCCCCEEEEECCEECCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEC
GFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQVEGATKLPTSPGYTGVTDYYIIRT
CCCCCCCCCHHHHHHHHHHHCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCCEEEEEEE
ENRPLLQPLRAVPVIGDPLADLIQPNLKVIVNLGYGDPNYGYSTSYADVRTPFGLWPNVP
CCCHHHHHHHHCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PQVIADALAAGTQEGILDFTADLQALSAQPLTLPQIQLPQPADLVAAVAAAPTPAEVVNT
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
LARIISTNYAVLLPTVDIALALVTTLPLYTTQLFVRQLAAGNLINAIGYPLAATVGLGTI
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCCCC
DSGRRGIAHPPRGGLGHRSKHRGPRHLTDSRRHRRPPTTVYRPRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYADAEAAIASTRQNQLAV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCCCEEC
PAAAPTPAAAAMIPPFPANLTTLFFGPTGIPLPPPSMLTPPIRCRSVRRALQAVFTPEEL
CCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHH
YPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVFGWSQSAIIASLEMQRFTAMG
CCHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHC
GAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDLTFYGATPSDTIYPTAIYTLEYD
CCCCCCCCCEEEEECCEECCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEC
GFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQVEGATKLPTSPGYTGVTDYYIIRT
CCCCCCCCCHHHHHHHHHHHCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCCEEEEEEE
ENRPLLQPLRAVPVIGDPLADLIQPNLKVIVNLGYGDPNYGYSTSYADVRTPFGLWPNVP
CCCHHHHHHHHCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PQVIADALAAGTQEGILDFTADLQALSAQPLTLPQIQLPQPADLVAAVAAAPTPAEVVNT
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
LARIISTNYAVLLPTVDIALALVTTLPLYTTQLFVRQLAAGNLINAIGYPLAATVGLGTI
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCCCC
DSGRRGIAHPPRGGLGHRSKHRGPRHLTDSRRHRRPPTTVYRPRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]