Click here to switch to the map view.

The map label for this gene is ppe28 [H]

Identifier: 148659915

GI number: 148659915

Start: 178903

End: 180669

Strand: Reverse

Name: ppe28 [H]

Synonym: MRA_0158

Alternate gene names: 148659915

Gene position: 180669-178903 (Counterclockwise)

Preceding gene: 148659916

Following gene: 148659914

Centisome position: 4.09

GC content: 61.74

Gene sequence:

>1767_bases
ATGGCCCCATTTGGGTTCACTCCAAAGGCCAGACACAACCGCGGAGTCGCTTTACGCTCAACGTATCGGCTCGACGGGTG
GGTTATGGGCCCCGTCGACAAGGAGGGATGGGGTTTGTCGTACGTATTCGCGCAGCCGTCGGTATTGGCAGCGGCGGCTA
CCGATTTGGCCGGGATCGGCTCGGCGATCAACCAGGCTACGGCGGCCGTCGCGGCCCCGACAACCGGCCTGGCGGCGGCT
GCCGCGGACGAAGTGTCCACGGCCCTTGCCACGCTGTTCGGCGCGTACGGCCAGCAGTTCCAGGCGATCAGCGCACAGGT
TGCGGCGTTTCACAACGAATTCACCCAGAGGTTGGCGGCGGCCGCAAACGCATTTGTCAATGCCGAGGCCACCAACACGA
GCGCGCTGGTGCAGGAGGCGACGGCCGGACTCTTTAAGCCAACCTCACCCCCGGTGCTACCGCCAATGTTCAACCAAAAT
ACGGCGATCATCATGGGCGGCACCGGGTCACCGATACCCACGCCGAGTTATGTCAACGCCATCACGACCTTGTTCATCGA
CCCCGTCGTCTCGAATCCGGTCGTCAAAGCGCTGGTGACGCCCGAAGAGCTATATCCGATCACCGGCGTCAAATCCCTGC
CCTTCCAAACCTCGGTGCAGTTGGGCCTACAGATTCTCGACGGCGCGATTTGGGAGCAAATCAACGCCGGAAACCACGTC
ACCGTGTTCGGCTATTCGCAGAGCGCCGTCATCGCGTCCCTGGAAATGCAGCACCTCATCTCGCTGGGTCCCAACGCTCC
CAGCCCCAGCCAGCTCAATTTCATCTTGATCGGCAACGAGATGAATCCCAATGGCGGGATACTTGCGCGCATACCCGGTC
TGAATGTCACCACCCTCGGCCTACCGTTCTACGGGGCGACCCCGGACAATCCCTATCCGACGACGACCTACACCCTCGAG
TACGACGGTTTCGCCGACTTCCCGCGGTATCCACTCAATGTCCTGTCCGATATCAACGCAGTATTCGGGATACTCACGGT
GCACACCACGTATGCGGACCTCACACCGGCACAGATAGCGTCGGCCACGCAGTTGCCGACACAGGGCACGACGTCGAACA
CGTACTACATCATTGAAACCGAGCATCTGCCGCTGCTGGCCCCGTTGCGGGCAATCCCGGTCATTGGCCCACCGCTGGCG
GCGCTGGTCGAACCGAACTTGGAAGTAATCGTCAATCTGGGTTACGGCGACCCGAGGTTCGGCTATTCGACGAGCCCGGC
GAACGTGCCTACCCCATTCGGGCTCTTCCCGGATGTCCCGGCGAGCGTTGTCGCCGATGCCCTGGTTGCCGGAACGCAAC
AGGGCGTCAACGACTTCATGGTCGAGTTGCCAGCCGCCCTGAACACCCTGCCCCAAACTCCGATGCCCGCGTTCCCGCCG
TATGTGCCGACGCTGCTACCGCCGCCACCGCCGCCACAACCGGCGACGCTCATCAACATCGCGGACACTTTCGCTTCCGT
TGTGTCGACCGGCTACTCGATTCTTCTTCCGACGGCAGATCTAGGTCTTGCCTTCGTCACTATCCTGCCCGCCTATGACC
TCACCCTGTTCGTGAATCAACTGGCGGCCGGCAACCTCCGCGCTGCGATCGAGCTGCCGCTCGCGGCCACCATTGGGTTG
GCCGCCCTGGGCGGCATGATTGAATTCATCGCGATTGTGGTGACGTTGGCCGACATTACTCAGCAACTGCAAAGCTTCAG
CATCTGA

Upstream 100 bases:

>100_bases
ACACCGTTCGAAACATCGAGGGCCTCGTCACCTAACGGATTCCCGACGGCATCGACGTCCACCGACTACCGTTTACCGAC
CTCGCCAATGACGAGGCAGC

Downstream 100 bases:

>100_bases
TCGCCCGATGCTCGGGTTCATTCAGCACTACTACGTGATCACCCCGGCCTGCCGCTGCTCGAGCCGCTGCCGGCCCTCGA
TCATGAAGAGCCGGTTTTCG

Product: PE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MAPFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFAQPSVLAAAATDLAGIGSAINQATAAVAAPTTGLAAA
AADEVSTALATLFGAYGQQFQAISAQVAAFHNEFTQRLAAAANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQN
TAIIMGGTGSPIPTPSYVNAITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTSVQLGLQILDGAIWEQINAGNHV
TVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFILIGNEMNPNGGILARIPGLNVTTLGLPFYGATPDNPYPTTTYTLE
YDGFADFPRYPLNVLSDINAVFGILTVHTTYADLTPAQIASATQLPTQGTTSNTYYIIETEHLPLLAPLRAIPVIGPPLA
ALVEPNLEVIVNLGYGDPRFGYSTSPANVPTPFGLFPDVPASVVADALVAGTQQGVNDFMVELPAALNTLPQTPMPAFPP
YVPTLLPPPPPPQPATLINIADTFASVVSTGYSILLPTADLGLAFVTILPAYDLTLFVNQLAAGNLRAAIELPLAATIGL
AALGGMIEFIAIVVTLADITQQLQSFSI

Sequences:

>Translated_588_residues
MAPFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFAQPSVLAAAATDLAGIGSAINQATAAVAAPTTGLAAA
AADEVSTALATLFGAYGQQFQAISAQVAAFHNEFTQRLAAAANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQN
TAIIMGGTGSPIPTPSYVNAITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTSVQLGLQILDGAIWEQINAGNHV
TVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFILIGNEMNPNGGILARIPGLNVTTLGLPFYGATPDNPYPTTTYTLE
YDGFADFPRYPLNVLSDINAVFGILTVHTTYADLTPAQIASATQLPTQGTTSNTYYIIETEHLPLLAPLRAIPVIGPPLA
ALVEPNLEVIVNLGYGDPRFGYSTSPANVPTPFGLFPDVPASVVADALVAGTQQGVNDFMVELPAALNTLPQTPMPAFPP
YVPTLLPPPPPPQPATLINIADTFASVVSTGYSILLPTADLGLAFVTILPAYDLTLFVNQLAAGNLRAAIELPLAATIGL
AALGGMIEFIAIVVTLADITQQLQSFSI
>Mature_587_residues
APFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFAQPSVLAAAATDLAGIGSAINQATAAVAAPTTGLAAAA
ADEVSTALATLFGAYGQQFQAISAQVAAFHNEFTQRLAAAANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQNT
AIIMGGTGSPIPTPSYVNAITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTSVQLGLQILDGAIWEQINAGNHVT
VFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFILIGNEMNPNGGILARIPGLNVTTLGLPFYGATPDNPYPTTTYTLEY
DGFADFPRYPLNVLSDINAVFGILTVHTTYADLTPAQIASATQLPTQGTTSNTYYIIETEHLPLLAPLRAIPVIGPPLAA
LVEPNLEVIVNLGYGDPRFGYSTSPANVPTPFGLFPDVPASVVADALVAGTQQGVNDFMVELPAALNTLPQTPMPAFPPY
VPTLLPPPPPPQPATLINIADTFASVVSTGYSILLPTADLGLAFVTILPAYDLTLFVNQLAAGNLRAAIELPLAATIGLA
ALGGMIEFIAIVVTLADITQQLQSFSI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 61412; Mature: 61281

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFAQPSVLAAAATDLAGIG
CCCCCCCCCCCCCCCEEEEEEEEECCEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
SAINQATAAVAAPTTGLAAAAADEVSTALATLFGAYGQQFQAISAQVAAFHNEFTQRLAA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQNTAIIMGGTGSPIPTPSYVNA
HHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHH
ITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTSVQLGLQILDGAIWEQINAGNHV
HHHHHHCHHHCCCHHEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
TVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFILIGNEMNPNGGILARIPGLNVTTLG
EEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECEECCCCCEEEEECCCCEEEEE
LPFYGATPDNPYPTTTYTLEYDGFADFPRYPLNVLSDINAVFGILTVHTTYADLTPAQIA
CEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEHHCCCCHHHHH
SATQLPTQGTTSNTYYIIETEHLPLLAPLRAIPVIGPPLAALVEPNLEVIVNLGYGDPRF
HHHCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCHHHHHCCCEEEEEECCCCCCCC
GYSTSPANVPTPFGLFPDVPASVVADALVAGTQQGVNDFMVELPAALNTLPQTPMPAFPP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
YVPTLLPPPPPPQPATLINIADTFASVVSTGYSILLPTADLGLAFVTILPAYDLTLFVNQ
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
LAAGNLRAAIELPLAATIGLAALGGMIEFIAIVVTLADITQQLQSFSI
HHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
APFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFAQPSVLAAAATDLAGIG
CCCCCCCCCCCCCCEEEEEEEEECCEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
SAINQATAAVAAPTTGLAAAAADEVSTALATLFGAYGQQFQAISAQVAAFHNEFTQRLAA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQNTAIIMGGTGSPIPTPSYVNA
HHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHH
ITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTSVQLGLQILDGAIWEQINAGNHV
HHHHHHCHHHCCCHHEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
TVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFILIGNEMNPNGGILARIPGLNVTTLG
EEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECEECCCCCEEEEECCCCEEEEE
LPFYGATPDNPYPTTTYTLEYDGFADFPRYPLNVLSDINAVFGILTVHTTYADLTPAQIA
CEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEHHCCCCHHHHH
SATQLPTQGTTSNTYYIIETEHLPLLAPLRAIPVIGPPLAALVEPNLEVIVNLGYGDPRF
HHHCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCHHHHHCCCEEEEEECCCCCCCC
GYSTSPANVPTPFGLFPDVPASVVADALVAGTQQGVNDFMVELPAALNTLPQTPMPAFPP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
YVPTLLPPPPPPQPATLINIADTFASVVSTGYSILLPTADLGLAFVTILPAYDLTLFVNQ
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
LAAGNLRAAIELPLAATIGLAALGGMIEFIAIVVTLADITQQLQSFSI
HHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]