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The map label for this gene is treS [H]

Identifier: 148659890

GI number: 148659890

Start: 153683

End: 155488

Strand: Direct

Name: treS [H]

Synonym: MRA_0133

Alternate gene names: 148659890

Gene position: 153683-155488 (Clockwise)

Preceding gene: 148659889

Following gene: 148659891

Centisome position: 3.48

GC content: 62.9

Gene sequence:

>1806_bases
ATGAACGAGGCAGAACACAGCGTCGAGCACCCTCCCGTGCAGGGCAGTCACGTCGAAGGCGGTGTGGTCGAGCATCCGGA
TGCCAAGGACTTCGGCAGCGCCGCCGCCCTGCCCGCCGATCCGACCTGGTTTAAGCACGCCGTCTTCTACGAGGTGCTGG
TCCGGGCGTTCTTCGACGCCAGCGCGGACGGTTCCGGCGATCTGCGTGGACTCATCGATCGCCTCGACTACCTGCAGTGG
CTTGGCATCGACTGCATCTGGTTGCCGCCGTTCTACGACTCGCCGCTGCGCGACGGCGGTTACGACATTCGCGACTTCTA
CAAGGTGCTGCCCGAATTCGGCACCGTCGACGATTTCGTCGCCCTGGTCGACGCCGCTCACCGGCGAGGTATCCGCATCA
TCACCGACCTGGTGATGAATCACACCTCGGAGTCGCACCCCTGGTTTCAGGAGTCCCGCCGCGACCCAGACGGACCGTAC
GGTGACTATTACGTGTGGAGCGACACCAGCGAGCGCTACACCGACGCCCGGATCATCTTCGTCGACACCGAAGAGTCGAA
CTGGTCATTCGATCCTGTCCGCCGACAGTTCTACTGGCACCGATTCTTCTCCCACCAACCGGATCTGAACTACGACAACC
CCGCCGTGCAAGAGGCGATGATCGACGTCATCCGCTTTTGGCTCGGCTTGGGCATCGACGGGTTTCGGTTGGACGCGGTG
CCCTATCTCTTTGAACGTGAGGGCACCAACTGCGAGAACCTGCCGGAAACACACGCTTTTCTCAAGCGAGTCCGCAAGGT
GGTGGACGACGAATTCCCCGGCCGGGTGCTGCTAGCCGAAGCCAATCAGTGGCCGGGCGATGTCGTCGAATATTTCGGTG
ATCCCAACACCGGTGGCGACGAGTGCCACATGGCCTTTCACTTCCCGCTGATGCCGCGCATCTTCATGGCCGTGCGCCGG
GAGTCCCGTTTTCCGATCTCGGAGATCATCGCCCAGACCCCACCAATCCCTGACATGGCGCAATGGGGGATATTTCTGCG
CAACCACGACGAGCTGACGTTAGAAATGGTCACCGACGAAGAGCGCGACTACATGTACGCCGAGTACGCCAAGGATCCAC
GGATGAAGGCGAATGTCGGAATCCGTCGTCGGCTTGCGCCGCTGCTCGACAACGACCGCAACCAGATCGAGCTGTTCACC
GCGCTGCTGCTGTCGCTGCCCGGCTCGCCGGTCCTCTACTACGGCGACGAGATCGGGATGGGCGACGTGATCTGGTTGGG
TGATCGCGACGGCGTGCGCATCCCGATGCAGTGGACACCGGACCGCAACGCGGGTTTCTCCACCGCCAACCCGGGTCGGC
TGTACCTGCCGCCCAGCCAGGACCCGGTTTACGGGTATCAGGCCGTCAACGTCGAGGCGCAACGCGACACCTCGACGTCG
CTGCTCAACTTCACTCGCACCATGCTGGCCGTGCGTCGCCGACACCCCGCGTTTGCGGTCGGCGCATTCCAGGAATTGGG
CGGGTCCAACCCGTCGGTGCTGGCCTACGTGCGTCAGGTGGCCGGCGATGACGGCGACACCGTGCTCTGTGTCAACAACC
TGTCGCGATTCCCGCAGCCCATCGAATTGGACTTGCAGCAATGGACCAACTACACGCCGGTCGAGCTGACCGGGCACGTG
GAGTTTCCACGCATCGGCCAGGTGCCCTATCTGCTGACGCTGCCAGGACACGGGTTCTACTGGTTCCAGTTGACCACACA
TGAGGTGGGGGCACCTCCCACTTGCGGGGGAGAGCGGCGCCTATGA

Upstream 100 bases:

>100_bases
CGGATACCACCCGCCGGCCGGCCAATTGGATTGGCGCCAGCCGTGATTGCCGCGTGAGCCCCCGAGTTCCGTCTCCCGTG
CGCGTGGCATCGTGGAAGCA

Downstream 100 bases:

>100_bases
CTCGCGCCGGCGACGATGCACAGCGAAGCGATGAGGAGGAGCGGCGCCTATGACTCGCGCCAGCGACGATGCACAGCGAA
GCGATGAGGAGGAGCGGCGC

Product: trehalose synthase TreS

Products: NA

Alternate protein names: Maltose alpha-D-glucosyltransferase [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDASADGSGDLRGLIDRLDYLQW
LGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPY
GDYYVWSDTSERYTDARIIFVDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGDECHMAFHFPLMPRIFMAVRR
ESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFT
ALLLSLPGSPVLYYGDEIGMGDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQPIELDLQQWTNYTPVELTGHV
EFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERRL

Sequences:

>Translated_601_residues
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDASADGSGDLRGLIDRLDYLQW
LGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPY
GDYYVWSDTSERYTDARIIFVDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGDECHMAFHFPLMPRIFMAVRR
ESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFT
ALLLSLPGSPVLYYGDEIGMGDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQPIELDLQQWTNYTPVELTGHV
EFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERRL
>Mature_601_residues
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDASADGSGDLRGLIDRLDYLQW
LGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPY
GDYYVWSDTSERYTDARIIFVDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGDECHMAFHFPLMPRIFMAVRR
ESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFT
ALLLSLPGSPVLYYGDEIGMGDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQPIELDLQQWTNYTPVELTGHV
EFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERRL

Specific function: Catalyzes the conversion of maltose into alpha,alpha- trehalose by transglucosylation [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=557, Percent_Identity=29.6229802513465, Blast_Score=233, Evalue=5e-61,
Organism=Escherichia coli, GI1790687, Length=552, Percent_Identity=28.804347826087, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081873, Length=370, Percent_Identity=28.1081081081081, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786604, Length=478, Percent_Identity=24.0585774058577, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=41.7582417582418, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32565753, Length=529, Percent_Identity=23.6294896030246, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25147709, Length=217, Percent_Identity=29.9539170506912, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321726, Length=569, Percent_Identity=28.2952548330404, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321731, Length=588, Percent_Identity=26.0204081632653, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319776, Length=581, Percent_Identity=26.3339070567986, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6322245, Length=567, Percent_Identity=26.1022927689594, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324416, Length=212, Percent_Identity=39.1509433962264, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322241, Length=212, Percent_Identity=39.1509433962264, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322021, Length=212, Percent_Identity=39.1509433962264, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24586593, Length=573, Percent_Identity=31.413612565445, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24586587, Length=525, Percent_Identity=32.7619047619048, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24583745, Length=589, Percent_Identity=30.0509337860781, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI45549022, Length=561, Percent_Identity=30.8377896613191, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24583747, Length=556, Percent_Identity=30.9352517985612, Blast_Score=230, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24586597, Length=573, Percent_Identity=31.064572425829, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24583749, Length=556, Percent_Identity=30.9352517985612, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24586599, Length=561, Percent_Identity=30.6595365418895, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI221330053, Length=563, Percent_Identity=30.0177619893428, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24586591, Length=530, Percent_Identity=31.1320754716981, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24586589, Length=562, Percent_Identity=30.9608540925267, Blast_Score=216, Evalue=5e-56,
Organism=Drosophila melanogaster, GI281360393, Length=507, Percent_Identity=29.9802761341223, Blast_Score=183, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012810 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =5.4.99.16 [H]

Molecular weight: Translated: 68594; Mature: 68594

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFV
CCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
ALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPYGDYYVWSDTSERYTDARIIF
HHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEE
VDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
EECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCC
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGD
CHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCC
ECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDE
CEEEEEECCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHCEEEECCCCEEEEEECCC
ERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFTALLLSLPGSPVLYYGDEIGM
CCCEEHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
GDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
CCEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCHHH
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQP
HHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCHHHCCCC
IELDLQQWTNYTPVELTGHVEFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERR
CEEHHHHCCCCCCEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCCC
L
C
>Mature Secondary Structure
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFV
CCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
ALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPYGDYYVWSDTSERYTDARIIF
HHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEE
VDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
EECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCC
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGD
CHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCC
ECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDE
CEEEEEECCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHCEEEECCCCEEEEEECCC
ERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFTALLLSLPGSPVLYYGDEIGM
CCCEEHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
GDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
CCEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCHHH
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQP
HHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCHHHCCCC
IELDLQQWTNYTPVELTGHVEFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERR
CEEHHHHCCCCCCEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645698 [H]