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The map label for this gene is oxyS [H]

Identifier: 148659881

GI number: 148659881

Start: 142559

End: 143503

Strand: Direct

Name: oxyS [H]

Synonym: MRA_0124

Alternate gene names: 148659881

Gene position: 142559-143503 (Clockwise)

Preceding gene: 148659879

Following gene: 148659883

Centisome position: 3.23

GC content: 63.6

Gene sequence:

>945_bases
GTGCTCTTCCGTCAGCTGGAGTACTTCGTCGCGGTCGCCCAGGAGCGGCATTTCGCTCGGGCCGCTGAGAAGTGCTACGT
GTCGCAACCTGCGCTGTCTTCGGCAATCGCCAAGCTCGAACGCGAACTCAACGTCACCCTGATCAATCGCGGACACAGTT
TCGAAGGCCTTACTCGCGAGGGTGAGCGGTTGGTGGTATGGGCCAAGCGGATACTTGCCGAGCACGCTGCGTTCAAGGCC
GAGGTGGATGCGGTGCGGTCCGGGATAACCGGGACGCTTCGGCTAGGCACGGTTCCCACCGCGTCAACGACGGCATCCCT
GGTGCTGTCGGCGTTTTGCTCGGCGCACCCGTTGGCGAAGGTGCAAGTCTGTTCCCGGCTGGCTGCGACCGAGCTGTACC
GACGGCTGCGCGAATTCGAGCTCGATGCCGTCATCGTGCACCCCGAGACCCAAGACAGTGATGATGTTGATCTGGTGCCG
CTCTATGAGGAGCAGTACGTGCTGTTGTCGCCGGCGGATATGCTGCCGCCGGGGACATCGACGTTGGTGTGGCGGGATGC
CGCGCAACTACCGTTGGCATTGCTCACTGCGGATATGCGGGACCGCCAGGTTATCGACGCCGCGTTCGCCGACCACGCGG
TCTCGGCGATCCCGCAGGTCGAAACCGATTCCGTTGCTTCGCTGTTCGCACAGGTGGCAACCGGCAACTGGGCGTCCATC
GTTCCGCACACCTGGCTATGGGCAATGCCAATGAGCGGGCCGACGGGTGGTGAGATCCGCGCGGTCGAATTGGTCGATCC
GGTGCTGAAAGCCCAGATCGCCCTGGCTACCAACGCCTTGGGACCGGGATCTCCGGTTGCCCGAGCGCTCATAACATGCG
CGCAGGCGCTGGCGCTGAACGAATTCTTTGACACGCAGCTGCGGGGGATCACCCGTCGCCGCTGA

Upstream 100 bases:

>100_bases
AGTTTCTGGATAGCCCCGCCGCCCCGCGGGTGCGGATTGGCAGGCCGCGCGGCCTCGCGTTAGCCTCAGCGGAATCGGTG
CCAAGGCCGAGGAGGTGCGG

Downstream 100 bases:

>100_bases
TCGCGGGCGTCGCTGCGCTGGTAGTGTTCAGCTTCGCCAGGTGGCCGCTCTCCACCCCGTCTGCAGGGTCGAGTTCGCAG
TCGATGAGTGACGGTCCGTT

Product: oxidative stress response regulatory protein OxyS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKA
EVDAVRSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVP
LYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIPQVETDSVASLFAQVATGNWASI
VPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR

Sequences:

>Translated_314_residues
MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKA
EVDAVRSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVP
LYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIPQVETDSVASLFAQVATGNWASI
VPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR
>Mature_314_residues
MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKA
EVDAVRSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVP
LYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIPQVETDSVASLFAQVATGNWASI
VPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=170, Percent_Identity=34.7058823529412, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788887, Length=179, Percent_Identity=36.8715083798883, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=261, Percent_Identity=26.8199233716475, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=28.8617886178862, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=169, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=299, Percent_Identity=26.7558528428094, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=122, Percent_Identity=34.4262295081967, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34224; Mature: 34224

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTRE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHH
VQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTS
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCEEEECCHHCCCCCCC
TLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIPQVETDSVASLFAQVATGNWASI
EEEECCHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHH
VPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALN
CCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EFFDTQLRGITRRR
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTRE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHH
VQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTS
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCEEEECCHHCCCCCCC
TLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIPQVETDSVASLFAQVATGNWASI
EEEECCHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHH
VPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALN
CCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EFFDTQLRGITRRR
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA