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The map label for this gene is gmhB [H]

Identifier: 148659877

GI number: 148659877

Start: 139300

End: 139872

Strand: Direct

Name: gmhB [H]

Synonym: MRA_0120

Alternate gene names: 148659877

Gene position: 139300-139872 (Clockwise)

Preceding gene: 148659876

Following gene: 148659878

Centisome position: 3.15

GC content: 61.61

Gene sequence:

>573_bases
ATGGTCGCGGAACGTGCGGGACACCAATGGTGTCTCTTCCTCGATAGAGACGGGGTCATCAATCGACAAGTGGTCGGCGA
CTACGTACGGAACTGGCGGCAGTTTGAATGGTTGCCCGGGGCGGCGCGGGCGTTGAAGAAGCTACGGGCATGGGCTCCGT
ACATCGTTGTCGTGACAAACCAGCAGGGCGTGGGTGCCGGATTGATGAGCGCCGTCGACGTGATGGTGATACATCGGCAC
CTCCAAATGCAGCTTGCATCCGATGGCGTGCTGATAGATGGATTTCAGGTTTGCCCGCACCACCGTTCGCAGCGGTGTGG
CTGCCGTAAGCCGAGACCGGGTCTGGTCCTCGACTGGCTCGGACGACACCCCGACAGTGAGCCATTGCTGAGCATCGTGG
TTGGGGACAGCCTCAGCGATCTTGAATTGGCACACAACGTCGCCGCTGCTGCCGGTGCATGTGCCAGTGTCCAGATAGGG
GGCGCCAGTTCTGGCGGTGTCGCTGACGCGTCATTTGACTCGCTCTGGGAGTTCGCTGTCGCAGTCGGACATGCGCGGGG
GGAGCGGGGCTAA

Upstream 100 bases:

>100_bases
TCTCACATCGTTTTTATTCATGCGATCTCCGAACATGTCGAACACGCGCTTTTCGCGCCTCGCCAATAGGAAAGCCGATC
CTTACGCGGCCATTCGAAAG

Downstream 100 bases:

>100_bases
TGGCGATCTTGCGCGGGCGAGCGCCGTTGCGGCTCGGACTCGGCGGTGGCGGGACAGACGTGGAACCGTACTCGAGCCAG
TTTGGCGGACGAATTCTTAG

Product: D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARALKKLRAWAPYIVVVTNQQGVGAGLMSAVDVMVIHRH
LQMQLASDGVLIDGFQVCPHHRSQRCGCRKPRPGLVLDWLGRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIG
GASSGGVADASFDSLWEFAVAVGHARGERG

Sequences:

>Translated_190_residues
MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARALKKLRAWAPYIVVVTNQQGVGAGLMSAVDVMVIHRH
LQMQLASDGVLIDGFQVCPHHRSQRCGCRKPRPGLVLDWLGRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIG
GASSGGVADASFDSLWEFAVAVGHARGERG
>Mature_190_residues
MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARALKKLRAWAPYIVVVTNQQGVGAGLMSAVDVMVIHRH
LQMQLASDGVLIDGFQVCPHHRSQRCGCRKPRPGLVLDWLGRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIG
GASSGGVADASFDSLWEFAVAVGHARGERG

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=184, Percent_Identity=34.7826086956522, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082027, Length=140, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20512; Mature: 20512

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARALKKLRAWAPYIVVVTN
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEC
QQGVGAGLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHRSQRCGCRKPRPGLVLDWL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEECCCCCCCCCCCCCCCCCEEEHHH
GRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIGGASSGGVADASFDSLWEFAV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AVGHARGERG
HHHHCCCCCC
>Mature Secondary Structure
MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARALKKLRAWAPYIVVVTN
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEC
QQGVGAGLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHRSQRCGCRKPRPGLVLDWL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEECCCCCCCCCCCCCCCCCEEEHHH
GRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIGGASSGGVADASFDSLWEFAV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AVGHARGERG
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]