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The map label for this gene is gyrA [H]

Identifier: 148652682

GI number: 148652682

Start: 1034672

End: 1037371

Strand: Direct

Name: gyrA [H]

Synonym: PsycPRwf_0873

Alternate gene names: 148652682

Gene position: 1034672-1037371 (Clockwise)

Preceding gene: 148652680

Following gene: 148652683

Centisome position: 34.73

GC content: 47.52

Gene sequence:

>2700_bases
ATGAGTGATTCGGTCAGTCCCATTGCCATCGTAGATGAGATGAAGCAATCCTACCTTGATTATGCGATGAGCGTTATTGT
GTCTCGAGCATTACCTGATGTGAGAGACGGGCTGAAACCTGTGCATCGCCGTATCATGTACGCCATGCATCAGCTGTCAA
ACGACTACAATAAACCCTATAAAAAATCGGCCCGTGTGGTCGGTGACGTAATCGGTAAATATCACCCTCATGGTGATACT
GCAGTGTATGATGCCATTGTGCGTATGGCGCAGGACTTTAGTCTTCGCTATCCTATGGTTGACGGTCAAGGTAACTTTGG
TTCTATCGATGATGACCCTGCTGCAGCGATGCGTTATACCGAAGTTCGTATGACCAAGCTGACGCATCAAATGCTGGGTG
ATTTGGACAAAGATACTGTCGATTGGGAAGACAACTACGACGGCTCTGAGCGTATGCCAAGCGTTCTGCCTGCTCGTATC
CCGAACCTATTGGTTAACGGTGCAACCGGTATTGCGGTTGGTATGGCCACCAACATGGCGCCACACAACTTAACTGAAGT
ATTAAATGCTTGCTTGGCCTATGCCGACAACCCCAATATCTCAAGTGAAGAGCTGACCAATTACATCTCTGGACCTGACT
TTCCTACCGGTGGCATTATCTATGGCCGCTCAGGTATCGTTGATGCATACCGTACCGGTAAAGGCCGCTTACACATTCGT
GGCCGCTATCATATTGAGCCGATGAGCGATACGGGTGTTAACCGTGATCGTGAGCGCATTGTATTTACCGAAATTCCTTA
TCAGTCTAACAAAGCCAAACTGATTGAGCGCATCGCAGAATTGGTTCGTGATAAAAAGATTGAGGGTATCTCTGAGATTC
GTGATGAGTCTGATAAAGACGGTATGCGTATTGCCATTGACCTGCGCCGCGGTGAAGTGGCTGAAGTTATCGTCAATAAC
TTATTCTTGCAGACCCCACTTGAGTCAAGCTTTAGCATTAACATGGTGGCCTTAGATAATGGCCAGCCAAAGCTTATGAC
CTTGCGTCAACTGATTGCCGCCTTCGTGCGTCACCGCCAAGAAGTGGTCACCCGCCGCACCATATTTGAATTAAATAAAG
CCAAAGCCCGTGGTCATTTGTTAGAAGGTTTGACCGTAGCGCTGGCCAATATCGATGACATCATCGCGACTATCAAAGAG
TCGGCCAACCGCGGTGAAGCTCGTGAGAAGCTATTGGCTCAGATTTGGGATTCAGGAACAGTTGTCGCTATGCTACAGGC
AGCGGGCCGTGGCACGCTAGCGGCGGGTGACCTACGCTCAGTACGCCCTGAATACATTGAGGGTGAGGATTTAAAAAATC
CGTTTGGCCTGATTGATCAAGGCAACAATTATCGTCTATCGCTTGAGCAGGTCAATGCTATCTTAGAGATGCAGCTGCAT
CGTCTAACCGGTCTTGAGCAAGATAAATTAACCGAAGAGTATCAAGACTTATTGCGTCAAATCGCTGAGCTTGAATCTAT
TTTGGCAGATTTTGATAAGCTGATGATGGTTATCAAAAATGAAATGCTTGAGATTTTAGAGAACTTCGGTGATGAGCGAC
GTACTGATATTGTTGACTCACGTACCGACTTTAGCCGTGAAGATTTAATCCCAGAGCAAACTGTGGTATTAACCGTATCT
CGTACCGGCTACGCTAAGACTCAGCCTATTAGCGATTATGTGGCACAAAAACGTGGTGGTAAGGGTAAATCTGCCACAGC
GATGAAAGAAGATGATGTGATTGATCACTTAGTGGTCACCTCAACGCACGCCACGGTACTTTGCTTTACCGATAACGGCC
GAGTGTTTAGCTTACGCGGCTTTGAAGTGCCGATTGCCAGCCGCGGTGCCCGTGGTCGCCCCTTAGTCAATATTATTGGG
CTTGAGCCAGATGAAATTGTCACCACCATCTTGCCAATTCCGAATTTATCAGAAGAAATTGACAGCCATTTTGTGTTCTT
TGCCACAGCGAACGGTACCGTTAAACGTGTCGAATTGTCACAATTTGCCAACATTCGCTCAAACGGTCTGATTGCTATTG
GCCTAGAAGAGGGTGATAAGCTGGTGTCTGCACGCATTACCAACGGCGAGCAACAAGTGATGCTGTTTGCCTCAAGTGGT
AAAGCCATCCGCTTTGATGAAAATGATGCCCGCGTCATGGGACGTACTGCCAAAGGCGTACGCGGTATGCGTATTGCAAA
TGATGAGTTTATCAAGTCGCTGGTAGTCATCGAAGAGGATGTGCAAGAGATTTTGATTGCTTGTGAAAATGGCTATGGTA
AACGTACCCCTGTTGATGAGTTTAATGCCCAAAACCGTGGCGGCGGTGGTGTGATTGCCATCAAGACCAGTGAACGTAAC
GGCGCACTCGTTCGTGCCACTAAGGTTCAGCCAGAAGATGATATTATCTTAATCTCTAACAAAGGTACTTTGGTGCGTAC
CCCCGTGGCTCAAGTAGCAACCTCAGGTCGTAACACGCAAGGGGTTACCTTAATCCGTTTATCTAAGGATGAAGCCTTAG
TGGCCATGGCACGAGTTGAAGATACCGGTGAAGAAGATGAGCTGGTTGAAGCCATGATTGAAAATGGCTTACTGACCGGT
GACGTACTTGACGCGGATAAAGACAGTGACGTTGTGGACCACTCTGATACTCTAGAGTAG

Upstream 100 bases:

>100_bases
TCATAAAATTCGTGATTGCCGGGCTAAAAAACCAAGCCAAACTTCATGCTAAAAAATCACGCCCAAAAATGAGATCAGCT
GCTAACATGGAGATGTATGT

Downstream 100 bases:

>100_bases
TTAGCTTGAGTAACAAAACAGTGCTATGACAACCCGCTTAGAGTGTATAGAATGCCGGCATAATCTGTCGGCATTTTTTA
TTTCATAATCAAGGATCGCT

Product: DNA gyrase subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 899; Mature: 898

Protein sequence:

>899_residues
MSDSVSPIAIVDEMKQSYLDYAMSVIVSRALPDVRDGLKPVHRRIMYAMHQLSNDYNKPYKKSARVVGDVIGKYHPHGDT
AVYDAIVRMAQDFSLRYPMVDGQGNFGSIDDDPAAAMRYTEVRMTKLTHQMLGDLDKDTVDWEDNYDGSERMPSVLPARI
PNLLVNGATGIAVGMATNMAPHNLTEVLNACLAYADNPNISSEELTNYISGPDFPTGGIIYGRSGIVDAYRTGKGRLHIR
GRYHIEPMSDTGVNRDRERIVFTEIPYQSNKAKLIERIAELVRDKKIEGISEIRDESDKDGMRIAIDLRRGEVAEVIVNN
LFLQTPLESSFSINMVALDNGQPKLMTLRQLIAAFVRHRQEVVTRRTIFELNKAKARGHLLEGLTVALANIDDIIATIKE
SANRGEAREKLLAQIWDSGTVVAMLQAAGRGTLAAGDLRSVRPEYIEGEDLKNPFGLIDQGNNYRLSLEQVNAILEMQLH
RLTGLEQDKLTEEYQDLLRQIAELESILADFDKLMMVIKNEMLEILENFGDERRTDIVDSRTDFSREDLIPEQTVVLTVS
RTGYAKTQPISDYVAQKRGGKGKSATAMKEDDVIDHLVVTSTHATVLCFTDNGRVFSLRGFEVPIASRGARGRPLVNIIG
LEPDEIVTTILPIPNLSEEIDSHFVFFATANGTVKRVELSQFANIRSNGLIAIGLEEGDKLVSARITNGEQQVMLFASSG
KAIRFDENDARVMGRTAKGVRGMRIANDEFIKSLVVIEEDVQEILIACENGYGKRTPVDEFNAQNRGGGGVIAIKTSERN
GALVRATKVQPEDDIILISNKGTLVRTPVAQVATSGRNTQGVTLIRLSKDEALVAMARVEDTGEEDELVEAMIENGLLTG
DVLDADKDSDVVDHSDTLE

Sequences:

>Translated_899_residues
MSDSVSPIAIVDEMKQSYLDYAMSVIVSRALPDVRDGLKPVHRRIMYAMHQLSNDYNKPYKKSARVVGDVIGKYHPHGDT
AVYDAIVRMAQDFSLRYPMVDGQGNFGSIDDDPAAAMRYTEVRMTKLTHQMLGDLDKDTVDWEDNYDGSERMPSVLPARI
PNLLVNGATGIAVGMATNMAPHNLTEVLNACLAYADNPNISSEELTNYISGPDFPTGGIIYGRSGIVDAYRTGKGRLHIR
GRYHIEPMSDTGVNRDRERIVFTEIPYQSNKAKLIERIAELVRDKKIEGISEIRDESDKDGMRIAIDLRRGEVAEVIVNN
LFLQTPLESSFSINMVALDNGQPKLMTLRQLIAAFVRHRQEVVTRRTIFELNKAKARGHLLEGLTVALANIDDIIATIKE
SANRGEAREKLLAQIWDSGTVVAMLQAAGRGTLAAGDLRSVRPEYIEGEDLKNPFGLIDQGNNYRLSLEQVNAILEMQLH
RLTGLEQDKLTEEYQDLLRQIAELESILADFDKLMMVIKNEMLEILENFGDERRTDIVDSRTDFSREDLIPEQTVVLTVS
RTGYAKTQPISDYVAQKRGGKGKSATAMKEDDVIDHLVVTSTHATVLCFTDNGRVFSLRGFEVPIASRGARGRPLVNIIG
LEPDEIVTTILPIPNLSEEIDSHFVFFATANGTVKRVELSQFANIRSNGLIAIGLEEGDKLVSARITNGEQQVMLFASSG
KAIRFDENDARVMGRTAKGVRGMRIANDEFIKSLVVIEEDVQEILIACENGYGKRTPVDEFNAQNRGGGGVIAIKTSERN
GALVRATKVQPEDDIILISNKGTLVRTPVAQVATSGRNTQGVTLIRLSKDEALVAMARVEDTGEEDELVEAMIENGLLTG
DVLDADKDSDVVDHSDTLE
>Mature_898_residues
SDSVSPIAIVDEMKQSYLDYAMSVIVSRALPDVRDGLKPVHRRIMYAMHQLSNDYNKPYKKSARVVGDVIGKYHPHGDTA
VYDAIVRMAQDFSLRYPMVDGQGNFGSIDDDPAAAMRYTEVRMTKLTHQMLGDLDKDTVDWEDNYDGSERMPSVLPARIP
NLLVNGATGIAVGMATNMAPHNLTEVLNACLAYADNPNISSEELTNYISGPDFPTGGIIYGRSGIVDAYRTGKGRLHIRG
RYHIEPMSDTGVNRDRERIVFTEIPYQSNKAKLIERIAELVRDKKIEGISEIRDESDKDGMRIAIDLRRGEVAEVIVNNL
FLQTPLESSFSINMVALDNGQPKLMTLRQLIAAFVRHRQEVVTRRTIFELNKAKARGHLLEGLTVALANIDDIIATIKES
ANRGEAREKLLAQIWDSGTVVAMLQAAGRGTLAAGDLRSVRPEYIEGEDLKNPFGLIDQGNNYRLSLEQVNAILEMQLHR
LTGLEQDKLTEEYQDLLRQIAELESILADFDKLMMVIKNEMLEILENFGDERRTDIVDSRTDFSREDLIPEQTVVLTVSR
TGYAKTQPISDYVAQKRGGKGKSATAMKEDDVIDHLVVTSTHATVLCFTDNGRVFSLRGFEVPIASRGARGRPLVNIIGL
EPDEIVTTILPIPNLSEEIDSHFVFFATANGTVKRVELSQFANIRSNGLIAIGLEEGDKLVSARITNGEQQVMLFASSGK
AIRFDENDARVMGRTAKGVRGMRIANDEFIKSLVVIEEDVQEILIACENGYGKRTPVDEFNAQNRGGGGVIAIKTSERNG
ALVRATKVQPEDDIILISNKGTLVRTPVAQVATSGRNTQGVTLIRLSKDEALVAMARVEDTGEEDELVEAMIENGLLTGD
VLDADKDSDVVDHSDTLE

Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]

COG id: COG0188

COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]

Homologues:

Organism=Escherichia coli, GI1788562, Length=871, Percent_Identity=55.9127439724455, Blast_Score=974, Evalue=0.0,
Organism=Escherichia coli, GI1789396, Length=758, Percent_Identity=33.245382585752, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI212645845, Length=363, Percent_Identity=23.9669421487603, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17136538, Length=374, Percent_Identity=26.2032085561497, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020899
- InterPro:   IPR005743
- InterPro:   IPR006691
- InterPro:   IPR002205
- InterPro:   IPR013758
- InterPro:   IPR013757
- InterPro:   IPR013760 [H]

Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]

EC number: =5.99.1.3 [H]

Molecular weight: Translated: 99464; Mature: 99333

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSVSPIAIVDEMKQSYLDYAMSVIVSRALPDVRDGLKPVHRRIMYAMHQLSNDYNKPY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KKSARVVGDVIGKYHPHGDTAVYDAIVRMAQDFSLRYPMVDGQGNFGSIDDDPAAAMRYT
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEECCEECCCCCCCCCCCCHHHHHHHH
EVRMTKLTHQMLGDLDKDTVDWEDNYDGSERMPSVLPARIPNLLVNGATGIAVGMATNMA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCHHHHHHCCHHEECCCCCEEEEHCCCCC
PHNLTEVLNACLAYADNPNISSEELTNYISGPDFPTGGIIYGRSGIVDAYRTGKGRLHIR
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCHHCCCCCEEEEE
GRYHIEPMSDTGVNRDRERIVFTEIPYQSNKAKLIERIAELVRDKKIEGISEIRDESDKD
EEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
GMRIAIDLRRGEVAEVIVNNLFLQTPLESSFSINMVALDNGQPKLMTLRQLIAAFVRHRQ
CCEEEEEECCCHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
EVVTRRTIFELNKAKARGHLLEGLTVALANIDDIIATIKESANRGEAREKLLAQIWDSGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VVAMLQAAGRGTLAAGDLRSVRPEYIEGEDLKNPFGLIDQGNNYRLSLEQVNAILEMQLH
EEEEEHHCCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
RLTGLEQDKLTEEYQDLLRQIAELESILADFDKLMMVIKNEMLEILENFGDERRTDIVDS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
RTDFSREDLIPEQTVVLTVSRTGYAKTQPISDYVAQKRGGKGKSATAMKEDDVIDHLVVT
CCCCCHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEE
STHATVLCFTDNGRVFSLRGFEVPIASRGARGRPLVNIIGLEPDEIVTTILPIPNLSEEI
ECCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHEEECCCCCHHHH
DSHFVFFATANGTVKRVELSQFANIRSNGLIAIGLEEGDKLVSARITNGEQQVMLFASSG
CCCEEEEEECCCCEEEEEHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEEECCC
KAIRFDENDARVMGRTAKGVRGMRIANDEFIKSLVVIEEDVQEILIACENGYGKRTPVDE
CEEEECCCCCCEECCHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
FNAQNRGGGGVIAIKTSERNGALVRATKVQPEDDIILISNKGTLVRTPVAQVATSGRNTQ
CCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCEEECCHHHHHHCCCCCC
GVTLIRLSKDEALVAMARVEDTGEEDELVEAMIENGLLTGDVLDADKDSDVVDHSDTLE
CEEEEEECCCCCEEEEEHHCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDSVSPIAIVDEMKQSYLDYAMSVIVSRALPDVRDGLKPVHRRIMYAMHQLSNDYNKPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KKSARVVGDVIGKYHPHGDTAVYDAIVRMAQDFSLRYPMVDGQGNFGSIDDDPAAAMRYT
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEECCEECCCCCCCCCCCCHHHHHHHH
EVRMTKLTHQMLGDLDKDTVDWEDNYDGSERMPSVLPARIPNLLVNGATGIAVGMATNMA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCHHHHHHCCHHEECCCCCEEEEHCCCCC
PHNLTEVLNACLAYADNPNISSEELTNYISGPDFPTGGIIYGRSGIVDAYRTGKGRLHIR
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCHHCCCCCEEEEE
GRYHIEPMSDTGVNRDRERIVFTEIPYQSNKAKLIERIAELVRDKKIEGISEIRDESDKD
EEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
GMRIAIDLRRGEVAEVIVNNLFLQTPLESSFSINMVALDNGQPKLMTLRQLIAAFVRHRQ
CCEEEEEECCCHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
EVVTRRTIFELNKAKARGHLLEGLTVALANIDDIIATIKESANRGEAREKLLAQIWDSGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VVAMLQAAGRGTLAAGDLRSVRPEYIEGEDLKNPFGLIDQGNNYRLSLEQVNAILEMQLH
EEEEEHHCCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
RLTGLEQDKLTEEYQDLLRQIAELESILADFDKLMMVIKNEMLEILENFGDERRTDIVDS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
RTDFSREDLIPEQTVVLTVSRTGYAKTQPISDYVAQKRGGKGKSATAMKEDDVIDHLVVT
CCCCCHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEE
STHATVLCFTDNGRVFSLRGFEVPIASRGARGRPLVNIIGLEPDEIVTTILPIPNLSEEI
ECCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHEEECCCCCHHHH
DSHFVFFATANGTVKRVELSQFANIRSNGLIAIGLEEGDKLVSARITNGEQQVMLFASSG
CCCEEEEEECCCCEEEEEHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEEECCC
KAIRFDENDARVMGRTAKGVRGMRIANDEFIKSLVVIEEDVQEILIACENGYGKRTPVDE
CEEEECCCCCCEECCHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
FNAQNRGGGGVIAIKTSERNGALVRATKVQPEDDIILISNKGTLVRTPVAQVATSGRNTQ
CCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCEEECCHHHHHHCCCCCC
GVTLIRLSKDEALVAMARVEDTGEEDELVEAMIENGLLTGDVLDADKDSDVVDHSDTLE
CEEEEEECCCCCEEEEEHHCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7811002; 10984043 [H]