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The map label for this gene is cobT [H]

Identifier: 148652652

GI number: 148652652

Start: 998370

End: 999479

Strand: Direct

Name: cobT [H]

Synonym: PsycPRwf_0843

Alternate gene names: 148652652

Gene position: 998370-999479 (Clockwise)

Preceding gene: 148652651

Following gene: 148652653

Centisome position: 33.51

GC content: 51.53

Gene sequence:

>1110_bases
TTGGACTGCTTAAACTTCCCCGCTATTGCTAATATCGATAATCCTCAATTGGCAGCTGATCTACAGCAGCTTCTGGATAA
CAAAACCAAGCCAATTGGTGCACTGGGCCGGCTAGAAACGCTAGCGCTAAAAATCGGGCTTATCCAAGGGACAACGCAGC
CAAAGATTGTTAGCCCGCACATTCGAGTGTTCGCCGCTGATCATGGGTTAACCAAACATAGTACGTCGGCTTTCCCTAGT
GAGGTAACGGCGCAAATGGTGCTCAATTTCTTAAAAGGGGGCGCGGCAATTAATGTGCTGGCTCGTCAGCATAATATTGA
GCTCAAGGTGGTCGATGCGGGCGTGGCCACTGACTTTGCTGAATATGGGGTAGACCATCATCCGCAGCTTTTGGATTACA
AAGTGCGCCTGGGGAGCCGTGATGCGCTCACTGAACCGGCCATGAATAGTGAAGAATGTATCGAAGCGCTTAAGGCAGGT
ATGCAGGTTGCCAAGTCTCTAAAAGGTAATCTGTTTATTGCAGGTGAGATGGGTATCGGTAATACCTCAGCAGCAAGCTT
ACTGCTCGCCAAGCTAGAAGATATACCTATTGCCCAGTGTGTTGGCCGTGGTACGGGACTTGATGATGCTGGCTTACAGC
ACAAAGTTGACGTGCTAAGCCAAGTATTGCAGCGTTATGAGCACGTGACCACGCCACTTGAAGTGTTGGCGGCTGTGGGC
GGGCTTGAGATTGCCATGATGGCCGGCGCCTTTATCCAAGCGGCCAGTGACCGACGTATTTTATTAATAGATGGTTTTAT
TGCCAGCAGTGCGCTACTGGTCGCAGAGCGTTTGGTACCCGGTGTGGCCCAATTTGCGATATTTGCCCATCAGTCGGTAG
AGCCTGGCCACAGCAGGATGTTGGCGGCGCTAGATGCTGAGCCCCTACTGGGCTTTGAGTTGCGATTGGGCGAGGGCAGT
GGTGCGGCGCTGGCGTATCCTTTATTGCAATCAGCGTGCGCCATTATCAATGAGATGGCAAGCTTTAGTGATGCGGGGAT
TAGCACGCAAAGTGAGCCAGGTTCACAAGCCAATATAGCCGCAGTTGTGGCCACTAGTGATGGGCAATAA

Upstream 100 bases:

>100_bases
ACGGCCAATAAAATTGAAGACAAAGAATTTAAGCAAGAGATTGATACGCTGCTGACCAAGTTGTTAACTCATTAATTTGT
TAGATCGATAAGGATGTACC

Downstream 100 bases:

>100_bases
CGCCAATGTCTGTTAAGCACGAGTGGCGCTTATTACAGGTTGCTACTCAGTTTTTGACCCGCATTCCTGTAAAAATGGAT
GATTATCAGGCTGACTGGTT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MDCLNFPAIANIDNPQLAADLQQLLDNKTKPIGALGRLETLALKIGLIQGTTQPKIVSPHIRVFAADHGLTKHSTSAFPS
EVTAQMVLNFLKGGAAINVLARQHNIELKVVDAGVATDFAEYGVDHHPQLLDYKVRLGSRDALTEPAMNSEECIEALKAG
MQVAKSLKGNLFIAGEMGIGNTSAASLLLAKLEDIPIAQCVGRGTGLDDAGLQHKVDVLSQVLQRYEHVTTPLEVLAAVG
GLEIAMMAGAFIQAASDRRILLIDGFIASSALLVAERLVPGVAQFAIFAHQSVEPGHSRMLAALDAEPLLGFELRLGEGS
GAALAYPLLQSACAIINEMASFSDAGISTQSEPGSQANIAAVVATSDGQ

Sequences:

>Translated_369_residues
MDCLNFPAIANIDNPQLAADLQQLLDNKTKPIGALGRLETLALKIGLIQGTTQPKIVSPHIRVFAADHGLTKHSTSAFPS
EVTAQMVLNFLKGGAAINVLARQHNIELKVVDAGVATDFAEYGVDHHPQLLDYKVRLGSRDALTEPAMNSEECIEALKAG
MQVAKSLKGNLFIAGEMGIGNTSAASLLLAKLEDIPIAQCVGRGTGLDDAGLQHKVDVLSQVLQRYEHVTTPLEVLAAVG
GLEIAMMAGAFIQAASDRRILLIDGFIASSALLVAERLVPGVAQFAIFAHQSVEPGHSRMLAALDAEPLLGFELRLGEGS
GAALAYPLLQSACAIINEMASFSDAGISTQSEPGSQANIAAVVATSDGQ
>Mature_369_residues
MDCLNFPAIANIDNPQLAADLQQLLDNKTKPIGALGRLETLALKIGLIQGTTQPKIVSPHIRVFAADHGLTKHSTSAFPS
EVTAQMVLNFLKGGAAINVLARQHNIELKVVDAGVATDFAEYGVDHHPQLLDYKVRLGSRDALTEPAMNSEECIEALKAG
MQVAKSLKGNLFIAGEMGIGNTSAASLLLAKLEDIPIAQCVGRGTGLDDAGLQHKVDVLSQVLQRYEHVTTPLEVLAAVG
GLEIAMMAGAFIQAASDRRILLIDGFIASSALLVAERLVPGVAQFAIFAHQSVEPGHSRMLAALDAEPLLGFELRLGEGS
GAALAYPLLQSACAIINEMASFSDAGISTQSEPGSQANIAAVVATSDGQ

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=331, Percent_Identity=32.9305135951662, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38697; Mature: 38697

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCLNFPAIANIDNPQLAADLQQLLDNKTKPIGALGRLETLALKIGLIQGTTQPKIVSPH
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEECCCCCCEECCC
IRVFAADHGLTKHSTSAFPSEVTAQMVLNFLKGGAAINVLARQHNIELKVVDAGVATDFA
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCHHHHHH
EYGVDHHPQLLDYKVRLGSRDALTEPAMNSEECIEALKAGMQVAKSLKGNLFIAGEMGIG
HCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
NTSAASLLLAKLEDIPIAQCVGRGTGLDDAGLQHKVDVLSQVLQRYEHVTTPLEVLAAVG
CHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GLEIAMMAGAFIQAASDRRILLIDGFIASSALLVAERLVPGVAQFAIFAHQSVEPGHSRM
CHHHHHHHHHHHEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHE
LAALDAEPLLGFELRLGEGSGAALAYPLLQSACAIINEMASFSDAGISTQSEPGSQANIA
EECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
AVVATSDGQ
EEEEECCCC
>Mature Secondary Structure
MDCLNFPAIANIDNPQLAADLQQLLDNKTKPIGALGRLETLALKIGLIQGTTQPKIVSPH
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEECCCCCCEECCC
IRVFAADHGLTKHSTSAFPSEVTAQMVLNFLKGGAAINVLARQHNIELKVVDAGVATDFA
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCHHHHHH
EYGVDHHPQLLDYKVRLGSRDALTEPAMNSEECIEALKAGMQVAKSLKGNLFIAGEMGIG
HCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
NTSAASLLLAKLEDIPIAQCVGRGTGLDDAGLQHKVDVLSQVLQRYEHVTTPLEVLAAVG
CHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GLEIAMMAGAFIQAASDRRILLIDGFIASSALLVAERLVPGVAQFAIFAHQSVEPGHSRM
CHHHHHHHHHHHEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHE
LAALDAEPLLGFELRLGEGSGAALAYPLLQSACAIINEMASFSDAGISTQSEPGSQANIA
EECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
AVVATSDGQ
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA