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The map label for this gene is frlR [H]

Identifier: 148652542

GI number: 148652542

Start: 874540

End: 875265

Strand: Direct

Name: frlR [H]

Synonym: PsycPRwf_0732

Alternate gene names: 148652542

Gene position: 874540-875265 (Clockwise)

Preceding gene: 148652541

Following gene: 148652545

Centisome position: 29.36

GC content: 35.81

Gene sequence:

>726_bases
ATGTTAAATAATTTTAAAGATTTTAAAATCCCACGCTATGAGCAAGTGCGTTGGCACATACAGACATTATTGACTGAGAG
TAAATGGGATGAGAATACGCCTTTACCTACAGAGCAGGAGTTTGCAGATAAGTATAAAGTATCGGTAGGAACCGTCCGTA
AAGCTGTTGAAAAACTAGTAGAAGAGGGGATTTTAATAAAGCAGCAAGGCAAAGGCACTTTTTTAAAGCGTCCAGACTTT
GAAAGCTCATTATTAAGGTTTTTTAAGTTCCGTGATAAAGACGCTGGCTATGGCACACCGACAGGTGTAATCAAAAAAAT
CATGGTAATAGACGGTATTGCTGATATTAATAAAAAACTTAATATAGGTAAAAACAAAGCTTTAATTTATATAGAACGAA
TGCGTATGGTTGAAGATAAAGTCTTGTTGAGTGAGAAGATTTGGTTACCTAAGAGTCGTTACGAAGCCTTTGCAACTTTA
GATCCTGAAGATTTTGAGAATCTTCTCTATCCGTTTTACTATAAAAAGTGCGGCCAGTTTGTGTCATCTGCGGTAGAGAC
ATTATTTTTTATAACTGACTATAAAGACCCTTATTTGGGCAATTCTGAGCAAGAAAGCTTGGTTAAGGTATGTCGTGTCG
CTAAAAATTTAGAAGGTGAGCCTATCGAATATAGAGAGTCCTATGGGCTAGCTGAGAAGTTCAGTTATGAAATTAATATT
ATTTGA

Upstream 100 bases:

>100_bases
AGGCTGCCTGATGAAATCTACCAAATGTTTTTCTCCGTTGTTGACAGCAGAGGTCAAGATTGAGACAGTTTATAAAAACG
TATCTATTTTGGTGAAAAAA

Downstream 100 bases:

>100_bases
TGGTGACTAAGCATGATTGTTTAAGCTAAGGGATATAAGATAAAAGGCAGTAACGTTAATAGGTTAGCGACTGCCAATCA
CTCAGCGGACATTTATATCT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLNNFKDFKIPRYEQVRWHIQTLLTESKWDENTPLPTEQEFADKYKVSVGTVRKAVEKLVEEGILIKQQGKGTFLKRPDF
ESSLLRFFKFRDKDAGYGTPTGVIKKIMVIDGIADINKKLNIGKNKALIYIERMRMVEDKVLLSEKIWLPKSRYEAFATL
DPEDFENLLYPFYYKKCGQFVSSAVETLFFITDYKDPYLGNSEQESLVKVCRVAKNLEGEPIEYRESYGLAEKFSYEINI
I

Sequences:

>Translated_241_residues
MLNNFKDFKIPRYEQVRWHIQTLLTESKWDENTPLPTEQEFADKYKVSVGTVRKAVEKLVEEGILIKQQGKGTFLKRPDF
ESSLLRFFKFRDKDAGYGTPTGVIKKIMVIDGIADINKKLNIGKNKALIYIERMRMVEDKVLLSEKIWLPKSRYEAFATL
DPEDFENLLYPFYYKKCGQFVSSAVETLFFITDYKDPYLGNSEQESLVKVCRVAKNLEGEPIEYRESYGLAEKFSYEINI
I
>Mature_241_residues
MLNNFKDFKIPRYEQVRWHIQTLLTESKWDENTPLPTEQEFADKYKVSVGTVRKAVEKLVEEGILIKQQGKGTFLKRPDF
ESSLLRFFKFRDKDAGYGTPTGVIKKIMVIDGIADINKKLNIGKNKALIYIERMRMVEDKVLLSEKIWLPKSRYEAFATL
DPEDFENLLYPFYYKKCGQFVSSAVETLFFITDYKDPYLGNSEQESLVKVCRVAKNLEGEPIEYRESYGLAEKFSYEINI
I

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=233, Percent_Identity=27.4678111587983, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790118, Length=235, Percent_Identity=23.8297872340426, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28180; Mature: 28180

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNFKDFKIPRYEQVRWHIQTLLTESKWDENTPLPTEQEFADKYKVSVGTVRKAVEKLV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EEGILIKQQGKGTFLKRPDFESSLLRFFKFRDKDAGYGTPTGVIKKIMVIDGIADINKKL
HCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHC
NIGKNKALIYIERMRMVEDKVLLSEKIWLPKSRYEAFATLDPEDFENLLYPFYYKKCGQF
CCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCHHHHHHHHHHHHHHHHHHH
VSSAVETLFFITDYKDPYLGNSEQESLVKVCRVAKNLEGEPIEYRESYGLAEKFSYEINI
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCCEEEEC
I
C
>Mature Secondary Structure
MLNNFKDFKIPRYEQVRWHIQTLLTESKWDENTPLPTEQEFADKYKVSVGTVRKAVEKLV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EEGILIKQQGKGTFLKRPDFESSLLRFFKFRDKDAGYGTPTGVIKKIMVIDGIADINKKL
HCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHC
NIGKNKALIYIERMRMVEDKVLLSEKIWLPKSRYEAFATLDPEDFENLLYPFYYKKCGQF
CCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCHHHHHHHHHHHHHHHHHHH
VSSAVETLFFITDYKDPYLGNSEQESLVKVCRVAKNLEGEPIEYRESYGLAEKFSYEINI
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCCEEEEC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]