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The map label for this gene is arsC [H]

Identifier: 148652485

GI number: 148652485

Start: 818334

End: 818792

Strand: Direct

Name: arsC [H]

Synonym: PsycPRwf_0674

Alternate gene names: 148652485

Gene position: 818334-818792 (Clockwise)

Preceding gene: 148652484

Following gene: 148652486

Centisome position: 27.47

GC content: 45.75

Gene sequence:

>459_bases
ATGCTGAGCGAACCTTGTACTTTTGTTGATTTAATCCCTAAGGAGACCAAAATGACGGCGACTATATTTCATAACCCAAA
GTGCAGCACTTCGCGCAATGCTTTGGCCATTATGCAAGCATCAGGTGAGACACCTGAGGTGATCGAGTATTTAAACACAC
CCCCAAGCCGTGAGTATTTGGTTAATTTGCTAAATCAGATGCACATGGCACCGCGTGAGCTGATGCGCAGCAAAGAAGCG
GTGTTTACTGAATTGGGCTTAGATAATCCTGAGGTGTCAGATGATCAACTCATCGATGCCATGATTAGCCACCCAATTTT
AATCAATCGACCGATTGTGGTGACAGACAAGGGCGCTGTGTTATGCCGTCCCTTAGAGCGGGTATTTGAGGTTTTAGCCA
CTCCTGTAGAGACATTTACTAAAGAAAATGGCGAGATTATTACCTACCCCGCGCTGTAG

Upstream 100 bases:

>100_bases
CATAAATAAGGCGGTGACATGCTGATTGTAGAACGCACTAGGGGGTTAATATCAGCAGGCTTATTTAGTCGCGACATTGA
TTAAATGGGCATGATTTTAT

Downstream 100 bases:

>100_bases
CTGAAGCCAACTAAAAGCCAGCTCAATGGGTTGATTTTGGCCGCTGGATCGCTTAATCTGTTTTGATTGTAGATACGCCC
TGAGCCTTACGGTTCAGGGC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLSEPCTFVDLIPKETKMTATIFHNPKCSTSRNALAIMQASGETPEVIEYLNTPPSREYLVNLLNQMHMAPRELMRSKEA
VFTELGLDNPEVSDDQLIDAMISHPILINRPIVVTDKGAVLCRPLERVFEVLATPVETFTKENGEIITYPAL

Sequences:

>Translated_152_residues
MLSEPCTFVDLIPKETKMTATIFHNPKCSTSRNALAIMQASGETPEVIEYLNTPPSREYLVNLLNQMHMAPRELMRSKEA
VFTELGLDNPEVSDDQLIDAMISHPILINRPIVVTDKGAVLCRPLERVFEVLATPVETFTKENGEIITYPAL
>Mature_152_residues
MLSEPCTFVDLIPKETKMTATIFHNPKCSTSRNALAIMQASGETPEVIEYLNTPPSREYLVNLLNQMHMAPRELMRSKEA
VFTELGLDNPEVSDDQLIDAMISHPILINRPIVVTDKGAVLCRPLERVFEVLATPVETFTKENGEIITYPAL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=126, Percent_Identity=50.7936507936508, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1788841, Length=113, Percent_Identity=43.3628318584071, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 17028; Mature: 17028

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEPCTFVDLIPKETKMTATIFHNPKCSTSRNALAIMQASGETPEVIEYLNTPPSREYL
CCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCHHHH
VNLLNQMHMAPRELMRSKEAVFTELGLDNPEVSDDQLIDAMISHPILINRPIVVTDKGAV
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEECCCEEEECCCCH
LCRPLERVFEVLATPVETFTKENGEIITYPAL
HHHHHHHHHHHHCCCHHHHHCCCCCEEEECCC
>Mature Secondary Structure
MLSEPCTFVDLIPKETKMTATIFHNPKCSTSRNALAIMQASGETPEVIEYLNTPPSREYL
CCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCHHHH
VNLLNQMHMAPRELMRSKEAVFTELGLDNPEVSDDQLIDAMISHPILINRPIVVTDKGAV
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEECCCEEEECCCCH
LCRPLERVFEVLATPVETFTKENGEIITYPAL
HHHHHHHHHHHHCCCHHHHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]