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The map label for this gene is hmp [H]

Identifier: 148652481

GI number: 148652481

Start: 814874

End: 816055

Strand: Direct

Name: hmp [H]

Synonym: PsycPRwf_0670

Alternate gene names: 148652481

Gene position: 814874-816055 (Clockwise)

Preceding gene: 148652480

Following gene: 148652482

Centisome position: 27.35

GC content: 46.87

Gene sequence:

>1182_bases
ATGGCATCACCCAAAACATTACAAGTCGTAAAAGCAACCGTTCCTGTGCTTGAAACTCATGGCACCCAGATTACTACGGT
CTTTTATCAAAATATGTTTGCTGAGCACCCTGAGCTTTTGGATATTTTTAATGAAACCAACCAAAAGCTAGGACGCCAGC
AAAGCGCTCTTGCGACCACAGTTTTGGCCGCAGCCAAGCATTTAGAGCAGTTAGAAGTATTATTACCGCAAGTGATGCAA
ATTGGTCATAAGCACCGCGCGTTACAGATTAAGCCTGAACATTATCCTATCGTTGGTAAACATTTATTGGGCGCCATCAA
GGAAGTACTGGGTGATGCCGCCACAGACGAGATTATCGAGGCTTGGGCAGAGGCGTATGCTGAGATTGCAGAGGTGTTTA
TCAAGGTAGAACAAAGCATGTACGAGCAGGCCATGTGGCCAGGCTTTGCGCCCTTTAAAGTGGTGGACAAACAAATCACC
GGCACAGACATCGCCGCCTTCACGGTACAGCCTGAAGACAGCAGCCTAGATATCCGTGCATTGCCATTAACAGCAGGTCA
GTACATTACTGTAAAAACCGACCCACAAGACAGTGACCATATTGCCTTAAGACATTATTCACTGTATTCAGTCGATAGCA
GCGACGGTATTAAATTTGCGGTACGCCGTGACAACCGTAATGCTCATCGCGGCTTGGTGTCTAACTACTTGCATGATCAT
GTGGAAGTTGGCGATACCATCTTACTCTCTGCACCGGCAGGGGATTTTGAATTAAATAAACCTCTTATTGAACAAAATGA
GGTGCCCTTGGTATTAATCAGTGCGGGCGTGGGCATTACACCAGTACTGGCTATGCTTGAGGCGCAAGTAAAAGCCAATC
CTAGTCGCCCTATCATCTGGGCTTATGCGTGCCAAAACCCAGAGTTTCAAGCCTTTGATACCCGCGTAGCGCAGCTACTA
GGCCAAGCTCAAAATGTACAACAGCACACCTTCTACTTTGAGCAAGGTCAACTATTAGATGAAAGCTGGCTAAAAACCCT
ACCTAATCCTGCCGATGTCTATGTGTGCGGCTCTATGGTCTTTATGGACAGCATGATTGATGGGTTAATGGCATTGGAGC
ACAGCGGCGATAACATCCACTATGAGCCCTTTGGTCCAAAAATGAGCCTAAACGTGGGCTAG

Upstream 100 bases:

>100_bases
AGTGATGAGCAAGGCTATTTTATTCGCTGCTTTATATTCTTTTACCTACCAACCCGTGCTCAATGCCGAGTTGCATACCC
TACTGATTAAGGAAATCACA

Downstream 100 bases:

>100_bases
ACGCCTTCAATGAAATTAAATCACGCTGTTCATCTGTAGCAGCAGCTCTATAAAGCTTGCCGATATTAAGATTAAGGCAG
CTTTATAGAGACATATGACT

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MASPKTLQVVKATVPVLETHGTQITTVFYQNMFAEHPELLDIFNETNQKLGRQQSALATTVLAAAKHLEQLEVLLPQVMQ
IGHKHRALQIKPEHYPIVGKHLLGAIKEVLGDAATDEIIEAWAEAYAEIAEVFIKVEQSMYEQAMWPGFAPFKVVDKQIT
GTDIAAFTVQPEDSSLDIRALPLTAGQYITVKTDPQDSDHIALRHYSLYSVDSSDGIKFAVRRDNRNAHRGLVSNYLHDH
VEVGDTILLSAPAGDFELNKPLIEQNEVPLVLISAGVGITPVLAMLEAQVKANPSRPIIWAYACQNPEFQAFDTRVAQLL
GQAQNVQQHTFYFEQGQLLDESWLKTLPNPADVYVCGSMVFMDSMIDGLMALEHSGDNIHYEPFGPKMSLNVG

Sequences:

>Translated_393_residues
MASPKTLQVVKATVPVLETHGTQITTVFYQNMFAEHPELLDIFNETNQKLGRQQSALATTVLAAAKHLEQLEVLLPQVMQ
IGHKHRALQIKPEHYPIVGKHLLGAIKEVLGDAATDEIIEAWAEAYAEIAEVFIKVEQSMYEQAMWPGFAPFKVVDKQIT
GTDIAAFTVQPEDSSLDIRALPLTAGQYITVKTDPQDSDHIALRHYSLYSVDSSDGIKFAVRRDNRNAHRGLVSNYLHDH
VEVGDTILLSAPAGDFELNKPLIEQNEVPLVLISAGVGITPVLAMLEAQVKANPSRPIIWAYACQNPEFQAFDTRVAQLL
GQAQNVQQHTFYFEQGQLLDESWLKTLPNPADVYVCGSMVFMDSMIDGLMALEHSGDNIHYEPFGPKMSLNVG
>Mature_392_residues
ASPKTLQVVKATVPVLETHGTQITTVFYQNMFAEHPELLDIFNETNQKLGRQQSALATTVLAAAKHLEQLEVLLPQVMQI
GHKHRALQIKPEHYPIVGKHLLGAIKEVLGDAATDEIIEAWAEAYAEIAEVFIKVEQSMYEQAMWPGFAPFKVVDKQITG
TDIAAFTVQPEDSSLDIRALPLTAGQYITVKTDPQDSDHIALRHYSLYSVDSSDGIKFAVRRDNRNAHRGLVSNYLHDHV
EVGDTILLSAPAGDFELNKPLIEQNEVPLVLISAGVGITPVLAMLEAQVKANPSRPIIWAYACQNPEFQAFDTRVAQLLG
QAQNVQQHTFYFEQGQLLDESWLKTLPNPADVYVCGSMVFMDSMIDGLMALEHSGDNIHYEPFGPKMSLNVG

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=409, Percent_Identity=36.6748166259169, Blast_Score=241, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6321673, Length=395, Percent_Identity=57.4683544303797, Blast_Score=431, Evalue=1e-121,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43565; Mature: 43434

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPKTLQVVKATVPVLETHGTQITTVFYQNMFAEHPELLDIFNETNQKLGRQQSALATT
CCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VLAAAKHLEQLEVLLPQVMQIGHKHRALQIKPEHYPIVGKHLLGAIKEVLGDAATDEIIE
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
AWAEAYAEIAEVFIKVEQSMYEQAMWPGFAPFKVVDKQITGTDIAAFTVQPEDSSLDIRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCEEEE
LPLTAGQYITVKTDPQDSDHIALRHYSLYSVDSSDGIKFAVRRDNRNAHRGLVSNYLHDH
EEECCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHH
VEVGDTILLSAPAGDFELNKPLIEQNEVPLVLISAGVGITPVLAMLEAQVKANPSRPIIW
HCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEE
AYACQNPEFQAFDTRVAQLLGQAQNVQQHTFYFEQGQLLDESWLKTLPNPADVYVCGSMV
EEECCCCCCHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHCCCCCCEEEHHHHH
FMDSMIDGLMALEHSGDNIHYEPFGPKMSLNVG
HHHHHHHHHHHHHCCCCCEEECCCCCEEEECCC
>Mature Secondary Structure 
ASPKTLQVVKATVPVLETHGTQITTVFYQNMFAEHPELLDIFNETNQKLGRQQSALATT
CCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VLAAAKHLEQLEVLLPQVMQIGHKHRALQIKPEHYPIVGKHLLGAIKEVLGDAATDEIIE
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
AWAEAYAEIAEVFIKVEQSMYEQAMWPGFAPFKVVDKQITGTDIAAFTVQPEDSSLDIRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCEEEE
LPLTAGQYITVKTDPQDSDHIALRHYSLYSVDSSDGIKFAVRRDNRNAHRGLVSNYLHDH
EEECCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHH
VEVGDTILLSAPAGDFELNKPLIEQNEVPLVLISAGVGITPVLAMLEAQVKANPSRPIIW
HCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEE
AYACQNPEFQAFDTRVAQLLGQAQNVQQHTFYFEQGQLLDESWLKTLPNPADVYVCGSMV
EEECCCCCCHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHCCCCCCEEEHHHHH
FMDSMIDGLMALEHSGDNIHYEPFGPKMSLNVG
HHHHHHHHHHHHHCCCCCEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]