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The map label for this gene is ppx [H]

Identifier: 148652143

GI number: 148652143

Start: 398881

End: 400401

Strand: Direct

Name: ppx [H]

Synonym: PsycPRwf_0331

Alternate gene names: 148652143

Gene position: 398881-400401 (Clockwise)

Preceding gene: 148652142

Following gene: 148652144

Centisome position: 13.39

GC content: 47.27

Gene sequence:

>1521_bases
ATGCCAAATAACTTTTTAGCGAATGATGAACTCATGGCGGCCATTGATATTGGCTCAAACAGCTTTCACCTTGCTATTGC
TCGCTTAGATCATGGAGAGGTGCGCAAAATTGCCTCTATGTCTGAAAAAGTGCAATTGGCTGCCGGTCTGGATAAAAATA
AAATCTTGAGCGAAGACGCTCAGCAGCGTGGACTAGAGTGCTTGGCCAGGTTTATGGGGCGGCTTGATTCAGTATCGCCT
GATAGACTGCGTATTGTCGCCACCAACGCCTTGCGTCAGGCCAAAAACGCTGATGAATTTATCCGCCGTGCCAATGAAAT
CTTACCAAAGCCCATTGAAATCATTGCTGGACGAGAAGAGGCACGCTTGATCTATTTGGGTGTGTCGCACACCAATGCCA
GTAGCGATAAGCGCTTGGTCATTGATATCGGTGGGGGCTCAACTGAGTTTATCATTGGTCAAGAGTTCGATCCGTTATTG
ACCGAAAGTCTACAAATGGGCTGTGTGGCCTATACCCAGTGGTTCTTTGAGTCTGGCGATATTACCGAAAGCGCTTTTCA
AGAAGCCATAGCCGATGCGCGCAAAGAGATTTTACGCATTAGCACCACCTATCAAAGAACCGGCTGGACCAGTGTGGTGG
GCTCAAGCGGTACGATTAAAGCTGTGCGTAATGTCTTGGTCTCTCAAGGTTGGTCGGATGAGCAAGAGCGCATTACCTAC
CAAGGTGTGAAAAACCTACAAAAGCATTTACTAAAAATTGGCCGTGTAGAAGACATTGATTTAGAAGGGGTAAAAGAGCA
CCGTAAAGCAGTATTCCCTGCTGGTGTGGCGGTACTGCGTGCGGCGATGAAGGTGCTGGGTATTGAAACCATTGCCTACT
CAGATGGGGCGCTGCGTGAAGGGGTGATGTATGATATGCTCGGCCGCTTCGCTAGTGAAGATGTGCGTGATCGCAGTGTA
CAGGCATTAATTGAGCGCTATTCTGTTGATAAAAGACAAGCTCAGCGCGTGGTGAAAAGCTGTGAGAACCTCTATGATCA
GACCCATGATGCTTTAGGGCTAAGCGGCGAAGACAATGACCTGCTACGCCGCACCGCTTATTTACATGAGATTGGTCTGG
CAATCAGTCATAGCGGCTATCATCATCACAGCGCCTATTTGCTGCTGCATTCAGATATTCCTGGATTCTCCCAAGTGGAT
CAAGGCCGAATGTCACAGTTGGCACGCAATCACAGACGCAAACTAAAAACCGAAAATTTTGAACAAGCGCTGGAAGTAGG
GGGCCCGAGTTTGGTATATTTGTGCCTCTTATTAAGGCTGGCCGTGTTGGTACATCGTAGCCGTAATGATCTAGATAAAA
GTGCGCTCAAACTGACAGTTATTGATAAAAATCACTGGCAAGTTAGTGTAGAATCGGACTCCGAAGACTATGCGTTACTG
GTATTCGATCTAAAAGACGATATTGATCAATTTAAAAAGTGGGGCGTTGAGCTTAGTGTGACTTGTGCTGGCGCCTACTA
A

Upstream 100 bases:

>100_bases
ACTGCCAAAATAGGGCATGATTTAATTCAAAACATGATTTAATTCAAAAATAGCCACTAACTTTTAATCGTTGCATTCAC
TTAAGGTAAGACACCCGCCT

Downstream 100 bases:

>100_bases
TCCATCAAACATCACACTATAAAATAATATAATTATAATTTAAGGATAAATCATGAGTTCTGTTTGGGAAAGTGTTGGAC
TGGCAAGGCATGCAAAGCGC

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MPNNFLANDELMAAIDIGSNSFHLAIARLDHGEVRKIASMSEKVQLAAGLDKNKILSEDAQQRGLECLARFMGRLDSVSP
DRLRIVATNALRQAKNADEFIRRANEILPKPIEIIAGREEARLIYLGVSHTNASSDKRLVIDIGGGSTEFIIGQEFDPLL
TESLQMGCVAYTQWFFESGDITESAFQEAIADARKEILRISTTYQRTGWTSVVGSSGTIKAVRNVLVSQGWSDEQERITY
QGVKNLQKHLLKIGRVEDIDLEGVKEHRKAVFPAGVAVLRAAMKVLGIETIAYSDGALREGVMYDMLGRFASEDVRDRSV
QALIERYSVDKRQAQRVVKSCENLYDQTHDALGLSGEDNDLLRRTAYLHEIGLAISHSGYHHHSAYLLLHSDIPGFSQVD
QGRMSQLARNHRRKLKTENFEQALEVGGPSLVYLCLLLRLAVLVHRSRNDLDKSALKLTVIDKNHWQVSVESDSEDYALL
VFDLKDDIDQFKKWGVELSVTCAGAY

Sequences:

>Translated_506_residues
MPNNFLANDELMAAIDIGSNSFHLAIARLDHGEVRKIASMSEKVQLAAGLDKNKILSEDAQQRGLECLARFMGRLDSVSP
DRLRIVATNALRQAKNADEFIRRANEILPKPIEIIAGREEARLIYLGVSHTNASSDKRLVIDIGGGSTEFIIGQEFDPLL
TESLQMGCVAYTQWFFESGDITESAFQEAIADARKEILRISTTYQRTGWTSVVGSSGTIKAVRNVLVSQGWSDEQERITY
QGVKNLQKHLLKIGRVEDIDLEGVKEHRKAVFPAGVAVLRAAMKVLGIETIAYSDGALREGVMYDMLGRFASEDVRDRSV
QALIERYSVDKRQAQRVVKSCENLYDQTHDALGLSGEDNDLLRRTAYLHEIGLAISHSGYHHHSAYLLLHSDIPGFSQVD
QGRMSQLARNHRRKLKTENFEQALEVGGPSLVYLCLLLRLAVLVHRSRNDLDKSALKLTVIDKNHWQVSVESDSEDYALL
VFDLKDDIDQFKKWGVELSVTCAGAY
>Mature_505_residues
PNNFLANDELMAAIDIGSNSFHLAIARLDHGEVRKIASMSEKVQLAAGLDKNKILSEDAQQRGLECLARFMGRLDSVSPD
RLRIVATNALRQAKNADEFIRRANEILPKPIEIIAGREEARLIYLGVSHTNASSDKRLVIDIGGGSTEFIIGQEFDPLLT
ESLQMGCVAYTQWFFESGDITESAFQEAIADARKEILRISTTYQRTGWTSVVGSSGTIKAVRNVLVSQGWSDEQERITYQ
GVKNLQKHLLKIGRVEDIDLEGVKEHRKAVFPAGVAVLRAAMKVLGIETIAYSDGALREGVMYDMLGRFASEDVRDRSVQ
ALIERYSVDKRQAQRVVKSCENLYDQTHDALGLSGEDNDLLRRTAYLHEIGLAISHSGYHHHSAYLLLHSDIPGFSQVDQ
GRMSQLARNHRRKLKTENFEQALEVGGPSLVYLCLLLRLAVLVHRSRNDLDKSALKLTVIDKNHWQVSVESDSEDYALLV
FDLKDDIDQFKKWGVELSVTCAGAY

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=479, Percent_Identity=41.1273486430063, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI48994966, Length=446, Percent_Identity=37.6681614349776, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 56556; Mature: 56425

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNFLANDELMAAIDIGSNSFHLAIARLDHGEVRKIASMSEKVQLAAGLDKNKILSEDA
CCCCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QQRGLECLARFMGRLDSVSPDRLRIVATNALRQAKNADEFIRRANEILPKPIEIIAGREE
HHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCHHHHHHHHHHHCCCCHHHHCCCCC
ARLIYLGVSHTNASSDKRLVIDIGGGSTEFIIGQEFDPLLTESLQMGCVAYTQWFFESGD
CEEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
ITESAFQEAIADARKEILRISTTYQRTGWTSVVGSSGTIKAVRNVLVSQGWSDEQERITY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHH
QGVKNLQKHLLKIGRVEDIDLEGVKEHRKAVFPAGVAVLRAAMKVLGIETIAYSDGALRE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCCCHHC
GVMYDMLGRFASEDVRDRSVQALIERYSVDKRQAQRVVKSCENLYDQTHDALGLSGEDND
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LLRRTAYLHEIGLAISHSGYHHHSAYLLLHSDIPGFSQVDQGRMSQLARNHRRKLKTENF
HHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
EQALEVGGPSLVYLCLLLRLAVLVHRSRNDLDKSALKLTVIDKNHWQVSVESDSEDYALL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCEEEE
VFDLKDDIDQFKKWGVELSVTCAGAY
EEECHHHHHHHHHCCCEEEEEEECCC
>Mature Secondary Structure 
PNNFLANDELMAAIDIGSNSFHLAIARLDHGEVRKIASMSEKVQLAAGLDKNKILSEDA
CCCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QQRGLECLARFMGRLDSVSPDRLRIVATNALRQAKNADEFIRRANEILPKPIEIIAGREE
HHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCHHHHHHHHHHHCCCCHHHHCCCCC
ARLIYLGVSHTNASSDKRLVIDIGGGSTEFIIGQEFDPLLTESLQMGCVAYTQWFFESGD
CEEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
ITESAFQEAIADARKEILRISTTYQRTGWTSVVGSSGTIKAVRNVLVSQGWSDEQERITY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHH
QGVKNLQKHLLKIGRVEDIDLEGVKEHRKAVFPAGVAVLRAAMKVLGIETIAYSDGALRE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCCCHHC
GVMYDMLGRFASEDVRDRSVQALIERYSVDKRQAQRVVKSCENLYDQTHDALGLSGEDND
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LLRRTAYLHEIGLAISHSGYHHHSAYLLLHSDIPGFSQVDQGRMSQLARNHRRKLKTENF
HHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
EQALEVGGPSLVYLCLLLRLAVLVHRSRNDLDKSALKLTVIDKNHWQVSVESDSEDYALL
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCEEEE
VFDLKDDIDQFKKWGVELSVTCAGAY
EEECHHHHHHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]