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The map label for this gene is paaF [H]

Identifier: 148651825

GI number: 148651825

Start: 11220

End: 12026

Strand: Direct

Name: paaF [H]

Synonym: PsycPRwf_0008

Alternate gene names: 148651825

Gene position: 11220-12026 (Clockwise)

Preceding gene: 148651823

Following gene: 148651826

Centisome position: 0.38

GC content: 50.93

Gene sequence:

>807_bases
ATGAGCAATAATAGCCAAAATAATGCCCCATTCACTCGTCTCACTTATCAACAAGATGGCCACATCTGCCTAATCGGTCT
GAACCGAGTCGATAAACGTAATGCTTTTGATAGCCATATGATTGCCCAGTTATCAAAGGCACTAACTGACTATGAAGCCG
ACAGTAATTTGCGCTGTGCGCTCATCTTTGCTCATGGCGAGCACTTTACCGCAGGTCTGGATCTCATGGAGCTACAAGAC
AAGCTTGATAAAGGGGTGTTTGCATTTGATGAGTCTCAAATCGATCCTTGGGGCATCAGTGGTAAGCTGCGTACCAAGCC
TGTGGTAGTGGCAGTACAAGGTACTTGTTTCACGGCCGGTATTGAGCTGATGCTAAATAGCGATGTGGTAATCGCCAGTG
ACGACTGCAACTTTGCCCAGATGGAAGTGCAGCGCGGCATCATGCCGTTTGGCGGAGCGACGGTGCGTTTTGTGGCGGCG
GCAGGTTGGCAAAAAGCCATGCCATATTTATTAACCGGTAAGCCCTTTGATGCCAATACTGCTGACAAATTAGGTTTGGT
GAGCGACGTGGTACCCAAAGGTGAGCAGTACGACCGGGCCTACGAGTTGGCAACTGAGATTAGCAAGGCGGCACCGCTAG
GCGTGCAAGGGGTATTGGCATCTGCATTAGACGGCGCGCGCAATGGGGCAGACAGTGCTATGGCCAATATCCACAGCTTT
TTACCGCCCTTATTTGAGTCGGAAGATGCCCGTGAGGGCGTGATGGCGATGGTTGAGCGCCGTGAGGCCAACTTTAAGGG
ACGTTAA

Upstream 100 bases:

>100_bases
AAGCCTTGTACATAAGATTATAGTGAAAGAGATGCTCGCTTGAGCTAAAAACAATACGAGCTAAATGCCGTCATCTATGA
TTTATAAAAGGATAATAATA

Downstream 100 bases:

>100_bases
GACCCAAGCCGCTCTTTAATTAATGCCTTGTTTAAAAAGCAGGGTTCAGCTAATTGGGTAGTATCAAGTTTGGCTTGAGT
AGACCAAAAATAGACTAAAA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSNNSQNNAPFTRLTYQQDGHICLIGLNRVDKRNAFDSHMIAQLSKALTDYEADSNLRCALIFAHGEHFTAGLDLMELQD
KLDKGVFAFDESQIDPWGISGKLRTKPVVVAVQGTCFTAGIELMLNSDVVIASDDCNFAQMEVQRGIMPFGGATVRFVAA
AGWQKAMPYLLTGKPFDANTADKLGLVSDVVPKGEQYDRAYELATEISKAAPLGVQGVLASALDGARNGADSAMANIHSF
LPPLFESEDAREGVMAMVERREANFKGR

Sequences:

>Translated_268_residues
MSNNSQNNAPFTRLTYQQDGHICLIGLNRVDKRNAFDSHMIAQLSKALTDYEADSNLRCALIFAHGEHFTAGLDLMELQD
KLDKGVFAFDESQIDPWGISGKLRTKPVVVAVQGTCFTAGIELMLNSDVVIASDDCNFAQMEVQRGIMPFGGATVRFVAA
AGWQKAMPYLLTGKPFDANTADKLGLVSDVVPKGEQYDRAYELATEISKAAPLGVQGVLASALDGARNGADSAMANIHSF
LPPLFESEDAREGVMAMVERREANFKGR
>Mature_267_residues
SNNSQNNAPFTRLTYQQDGHICLIGLNRVDKRNAFDSHMIAQLSKALTDYEADSNLRCALIFAHGEHFTAGLDLMELQDK
LDKGVFAFDESQIDPWGISGKLRTKPVVVAVQGTCFTAGIELMLNSDVVIASDDCNFAQMEVQRGIMPFGGATVRFVAAA
GWQKAMPYLLTGKPFDANTADKLGLVSDVVPKGEQYDRAYELATEISKAAPLGVQGVLASALDGARNGADSAMANIHSFL
PPLFESEDAREGVMAMVERREANFKGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=29.6442687747036, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI70995211, Length=273, Percent_Identity=27.4725274725275, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4502327, Length=270, Percent_Identity=24.4444444444444, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542718, Length=193, Percent_Identity=30.5699481865285, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787659, Length=260, Percent_Identity=29.6153846153846, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=29.9242424242424, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787660, Length=273, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082183, Length=252, Percent_Identity=25.7936507936508, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788597, Length=264, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790281, Length=165, Percent_Identity=29.6969696969697, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=29.2079207920792, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=27.0161290322581, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=30.8641975308642, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=196, Percent_Identity=29.0816326530612, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=264, Percent_Identity=23.8636363636364, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=216, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535521, Length=210, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650670, Length=207, Percent_Identity=32.3671497584541, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357171, Length=205, Percent_Identity=30.2439024390244, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI20129971, Length=270, Percent_Identity=28.1481481481481, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24653477, Length=270, Percent_Identity=28.1481481481481, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24653139, Length=282, Percent_Identity=28.0141843971631, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19920382, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29111; Mature: 28980

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNSQNNAPFTRLTYQQDGHICLIGLNRVDKRNAFDSHMIAQLSKALTDYEADSNLRCA
CCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEE
LIFAHGEHFTAGLDLMELQDKLDKGVFAFDESQIDPWGISGKLRTKPVVVAVQGTCFTAG
EEEECCCEEECCCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEECCCEEEEEECCEEEEC
IELMLNSDVVIASDDCNFAQMEVQRGIMPFGGATVRFVAAAGWQKAMPYLLTGKPFDANT
EEEEECCCEEEEECCCCHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCEEEECCCCCCCC
ADKLGLVSDVVPKGEQYDRAYELATEISKAAPLGVQGVLASALDGARNGADSAMANIHSF
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LPPLFESEDAREGVMAMVERREANFKGR
CCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNNSQNNAPFTRLTYQQDGHICLIGLNRVDKRNAFDSHMIAQLSKALTDYEADSNLRCA
CCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEE
LIFAHGEHFTAGLDLMELQDKLDKGVFAFDESQIDPWGISGKLRTKPVVVAVQGTCFTAG
EEEECCCEEECCCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEECCCEEEEEECCEEEEC
IELMLNSDVVIASDDCNFAQMEVQRGIMPFGGATVRFVAAAGWQKAMPYLLTGKPFDANT
EEEEECCCEEEEECCCCHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCEEEECCCCCCCC
ADKLGLVSDVVPKGEQYDRAYELATEISKAAPLGVQGVLASALDGARNGADSAMANIHSF
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LPPLFESEDAREGVMAMVERREANFKGR
CCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]