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The map label for this gene is hmp [H]

Identifier: 148550735

GI number: 148550735

Start: 197672

End: 198121

Strand: Direct

Name: hmp [H]

Synonym: Swit_5299

Alternate gene names: 148550735

Gene position: 197672-198121 (Clockwise)

Preceding gene: 148550734

Following gene: 148550736

Centisome position: 63.72

GC content: 66.0

Gene sequence:

>450_bases
ATGCGTACTGCCTCCCCCGCCGCCATGGAGATCGTAAAGGCGACGGCTCCCGCTCTCGAAAAGCACGGAGTGGAAATCAC
CACGGCCATGTATGCCCGGCTGCTGCAGGACCCCGAAATCGCCGCCATGTTCGATCGCGCGGCGCAGGAAAGCGGTGAGC
AGCCGCGCCGGCTGGCCGGCGCGATCCTGGCCTATGCCAAGAACATCGACAAGCTCCAGAACCTTGGAAGCGCCGTGCAT
CGCATGGTCGCCCGGCACGTCGAGACCGGCGTCAGGCCCGAGCATTATCCCCATGTCGCGGGCGCTCTCCTTCCGGCGAT
CCGTGAGGTGCTGGGCGCCGAAGTCGCCACGGACGACGTGCTGGCTGCCTGGGGCGAAGCCTATTGGATGCTTGCCGACA
TTCTCATCGCCGCCGAAACGCAGGCCTATGAAGAGGCCAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GGCCCGGTCCGCTTCCACGTTGAATTCCTAAGGGTGGATTGATCGCCGCACCGGCACGTCCTCTCTTCCCAACCTCGATA
GCCTATCAAGGAGTTCCCTT

Downstream 100 bases:

>100_bases
TCGGTCGCGGGGAGCATCCTTTCCCGAGGCAGCCGACAGGAGAGCTTTAACCAAGTTGCGATATCGCGAGTCCATGCCCG
CAGCTGTCCGTCTTCTCCGC

Product: nitric oxide dioxygenase

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRTASPAAMEIVKATAPALEKHGVEITTAMYARLLQDPEIAAMFDRAAQESGEQPRRLAGAILAYAKNIDKLQNLGSAVH
RMVARHVETGVRPEHYPHVAGALLPAIREVLGAEVATDDVLAAWGEAYWMLADILIAAETQAYEEASAA

Sequences:

>Translated_149_residues
MRTASPAAMEIVKATAPALEKHGVEITTAMYARLLQDPEIAAMFDRAAQESGEQPRRLAGAILAYAKNIDKLQNLGSAVH
RMVARHVETGVRPEHYPHVAGALLPAIREVLGAEVATDDVLAAWGEAYWMLADILIAAETQAYEEASAA
>Mature_149_residues
MRTASPAAMEIVKATAPALEKHGVEITTAMYARLLQDPEIAAMFDRAAQESGEQPRRLAGAILAYAKNIDKLQNLGSAVH
RMVARHVETGVRPEHYPHVAGALLPAIREVLGAEVATDDVLAAWGEAYWMLADILIAAETQAYEEASAA

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=138, Percent_Identity=35.5072463768116, Blast_Score=86, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321673, Length=137, Percent_Identity=45.985401459854, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 16017; Mature: 16017

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTASPAAMEIVKATAPALEKHGVEITTAMYARLLQDPEIAAMFDRAAQESGEQPRRLAG
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
AILAYAKNIDKLQNLGSAVHRMVARHVETGVRPEHYPHVAGALLPAIREVLGAEVATDDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
LAAWGEAYWMLADILIAAETQAYEEASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTASPAAMEIVKATAPALEKHGVEITTAMYARLLQDPEIAAMFDRAAQESGEQPRRLAG
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
AILAYAKNIDKLQNLGSAVHRMVARHVETGVRPEHYPHVAGALLPAIREVLGAEVATDDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
LAAWGEAYWMLADILIAAETQAYEEASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]