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The map label for this gene is ybhB [C]

Identifier: 148550724

GI number: 148550724

Start: 187727

End: 189580

Strand: Direct

Name: ybhB [C]

Synonym: Swit_5288

Alternate gene names: 148550724

Gene position: 187727-189580 (Clockwise)

Preceding gene: 148550723

Following gene: 148550725

Centisome position: 60.51

GC content: 66.72

Gene sequence:

>1854_bases
GTGAAGCTCAGCGCTATCCTCGCCGGCACCTGCGCCGCACTCGCCCTGTCGACCGCCGCTTATGCGCAGCAGGGGGATGG
CACCGACGTTCAGGTCGCGATCCATGTCTTCAAGCCGGACAAGGCCCCGGCGATACCCGAGCGGCTCGCCGGGCTCAAGA
CGCCTGCAGGTTTCACGGTCACGACCTTCGCCACGGGCCTCAAGAATCCGCGGATCATTGCCGTGGCGCCCAATGGCGGG
ATCTATGTCAGCCGGCGCGAGCAGGGCGACGTCGTACTCCTGAAGGACGCCGACGGAAATGGCGTGGCCGATGGGCCGCC
GGTGGTCGTTGCGAACCGCCCGAGCGCCCACGGCCTCGCGATCAAGGACAACAAGCTCTACATCGCGACGGTGAAGGAGA
TTTTCGTCGCCGACATCCGGCCCGACGGCATGCTCGGACCGCTCCAGATGATCGTCGGCGACTTGCCCGATGGCGGCCAG
CACCCCAATCGGACGATGGCCTTCGGACCTGACGGCATGCTCTATGTGAGCGTGGGCTCCACCTGCAATGCGTGCAACGA
GAGCAATCCTGAAAACGCATCGATCCTGCGTGTCTCGCCCGATGGGAAGACCCGGACGATCTTCGCCCGTAATCTGCGCA
ACACGATCGGCTTCGGCTGGCATCCGGCGACCGGCGAGCTGTGGGGAATGGACCACGGCATCGACGATCTCGGCGACGAC
CAACAGCCCGAAGAGCTGAACCGCATCGAGCAGGGCAAGCAATATGGCTGGCCTCATGCCTTCGGCGCTGGCGCGATCCA
CCCCCAGACGACCCCGCCCGGGGAGATCACCAAGGCCCAGTGGCTTGCGGCAAGCACGCCGATGGTGCTCGGCTACACCG
CGCACGCCGCGCCGATGAGCCTCGTCTTCTATTCGGGCGGCAATTTCCCGGCCGAGTTCCAGAACGATGCCTTCGTTGCG
ATGCGCGGATCATGGAACCGCAAACCGGCCTCGGGCTACGAGATCGTACGGATCCGCTTCCAGAACGGTCAGCCGCAACG
CTTCGAGCCCTTTGTCACGGGTTTCCTGACCGACGACGGGACGCGCCATATCGCCCGTCCCGTTGGCCTCGCCATGCTGA
AGGACGGCTCGCTGCTCCTTTCGGACGATGGCAATGGCACGATTTTCCGCGTTGCCTACACGGGCGGGGCCGCAGCCCCC
ACCGCAGCAGCCGTGCCGCCCGCGCAGCCAATGCTTGCGCAGGCCGCCAAGGGTGTGGGGGTCCCGCTGGTACTCGACCG
GCCCGAGACGGCTGGTGCCCGCGGCCGGATTGCGGTGCGTTCGCCCGCCATCGCGCCGCAGGCGCTGATCCCTGAACGCT
ATAGCGAATATGCCGATGCGGTGTCGCCGCCGCTTGCGTGGGATCCCGTGCCCGGCGCGCAGTCCTATGTGCTCATCATG
GAGGACCCGGACTCGCTGCCGATCAATCCGTTCGTCCATTGGGTCGCCTGGAATATTCCGCCCTCGACGACCAGCCTTCC
CGAAGGTCTGCAGGAGCAGGAGCGGCTGACCTTGCCGGATGGCATGATGCAAGGGCGCAACAGCCGAAATACGCCCGGAT
ATTTCGGCCCGCAGCCGCCGGTCGGTGACCCCGCGCATCGCTACGCATTCCAGGTGCTGGCGCTAGACAAGGCCCTCGAT
CTGCCGATCGGCGCAGACCGCGATCAGGTGCTTGCCGCCGCGCAGGGCCACGTCATCGCCAAGGGCTCGCTCGTGGGCCG
CTACCGCCAGGCCGAGAAGCCGCCGAAGTCGGGCGTCCTGCCCGCGGGCGTCGCCAAGACGGTCGGAACCAAGATGCCCG
CGACCCGCCGCTGA

Upstream 100 bases:

>100_bases
GCACGGCCGCCACCGGTGCGATCCCGATCATCAAGCAGCACCTCGAGCATGCGCGTTCGCTCAAGAGCGGCCTGTGAAAC
CGATAAGCCAAGGAGAGACC

Downstream 100 bases:

>100_bases
CGACCGAACGAGAGGCTGGTGCGCGGTGCGCACCGGCTTTTCCGCTGCGGCTAATTTCCCTCGGTTTGAAGGTCCGGTCG
TTTCGGCGACGTGTCGGTTA

Product: PEBP family protein

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKLSAILAGTCAALALSTAAYAQQGDGTDVQVAIHVFKPDKAPAIPERLAGLKTPAGFTVTTFATGLKNPRIIAVAPNGG
IYVSRREQGDVVLLKDADGNGVADGPPVVVANRPSAHGLAIKDNKLYIATVKEIFVADIRPDGMLGPLQMIVGDLPDGGQ
HPNRTMAFGPDGMLYVSVGSTCNACNESNPENASILRVSPDGKTRTIFARNLRNTIGFGWHPATGELWGMDHGIDDLGDD
QQPEELNRIEQGKQYGWPHAFGAGAIHPQTTPPGEITKAQWLAASTPMVLGYTAHAAPMSLVFYSGGNFPAEFQNDAFVA
MRGSWNRKPASGYEIVRIRFQNGQPQRFEPFVTGFLTDDGTRHIARPVGLAMLKDGSLLLSDDGNGTIFRVAYTGGAAAP
TAAAVPPAQPMLAQAAKGVGVPLVLDRPETAGARGRIAVRSPAIAPQALIPERYSEYADAVSPPLAWDPVPGAQSYVLIM
EDPDSLPINPFVHWVAWNIPPSTTSLPEGLQEQERLTLPDGMMQGRNSRNTPGYFGPQPPVGDPAHRYAFQVLALDKALD
LPIGADRDQVLAAAQGHVIAKGSLVGRYRQAEKPPKSGVLPAGVAKTVGTKMPATRR

Sequences:

>Translated_617_residues
MKLSAILAGTCAALALSTAAYAQQGDGTDVQVAIHVFKPDKAPAIPERLAGLKTPAGFTVTTFATGLKNPRIIAVAPNGG
IYVSRREQGDVVLLKDADGNGVADGPPVVVANRPSAHGLAIKDNKLYIATVKEIFVADIRPDGMLGPLQMIVGDLPDGGQ
HPNRTMAFGPDGMLYVSVGSTCNACNESNPENASILRVSPDGKTRTIFARNLRNTIGFGWHPATGELWGMDHGIDDLGDD
QQPEELNRIEQGKQYGWPHAFGAGAIHPQTTPPGEITKAQWLAASTPMVLGYTAHAAPMSLVFYSGGNFPAEFQNDAFVA
MRGSWNRKPASGYEIVRIRFQNGQPQRFEPFVTGFLTDDGTRHIARPVGLAMLKDGSLLLSDDGNGTIFRVAYTGGAAAP
TAAAVPPAQPMLAQAAKGVGVPLVLDRPETAGARGRIAVRSPAIAPQALIPERYSEYADAVSPPLAWDPVPGAQSYVLIM
EDPDSLPINPFVHWVAWNIPPSTTSLPEGLQEQERLTLPDGMMQGRNSRNTPGYFGPQPPVGDPAHRYAFQVLALDKALD
LPIGADRDQVLAAAQGHVIAKGSLVGRYRQAEKPPKSGVLPAGVAKTVGTKMPATRR
>Mature_617_residues
MKLSAILAGTCAALALSTAAYAQQGDGTDVQVAIHVFKPDKAPAIPERLAGLKTPAGFTVTTFATGLKNPRIIAVAPNGG
IYVSRREQGDVVLLKDADGNGVADGPPVVVANRPSAHGLAIKDNKLYIATVKEIFVADIRPDGMLGPLQMIVGDLPDGGQ
HPNRTMAFGPDGMLYVSVGSTCNACNESNPENASILRVSPDGKTRTIFARNLRNTIGFGWHPATGELWGMDHGIDDLGDD
QQPEELNRIEQGKQYGWPHAFGAGAIHPQTTPPGEITKAQWLAASTPMVLGYTAHAAPMSLVFYSGGNFPAEFQNDAFVA
MRGSWNRKPASGYEIVRIRFQNGQPQRFEPFVTGFLTDDGTRHIARPVGLAMLKDGSLLLSDDGNGTIFRVAYTGGAAAP
TAAAVPPAQPMLAQAAKGVGVPLVLDRPETAGARGRIAVRSPAIAPQALIPERYSEYADAVSPPLAWDPVPGAQSYVLIM
EDPDSLPINPFVHWVAWNIPPSTTSLPEGLQEQERLTLPDGMMQGRNSRNTPGYFGPQPPVGDPAHRYAFQVLALDKALD
LPIGADRDQVLAAAQGHVIAKGSLVGRYRQAEKPPKSGVLPAGVAKTVGTKMPATRR

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

Organism=Escherichia coli, GI1786990, Length=132, Percent_Identity=37.8787878787879, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786757, Length=141, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 65437; Mature: 65437

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSAILAGTCAALALSTAAYAQQGDGTDVQVAIHVFKPDKAPAIPERLAGLKTPAGFTV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHCCCCCCCEEE
TTFATGLKNPRIIAVAPNGGIYVSRREQGDVVLLKDADGNGVADGPPVVVANRPSAHGLA
EEEHHCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEE
IKDNKLYIATVKEIFVADIRPDGMLGPLQMIVGDLPDGGQHPNRTMAFGPDGMLYVSVGS
EECCEEEEEEEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECC
TCNACNESNPENASILRVSPDGKTRTIFARNLRNTIGFGWHPATGELWGMDHGIDDLGDD
CCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
QQPEELNRIEQGKQYGWPHAFGAGAIHPQTTPPGEITKAQWLAASTPMVLGYTAHAAPMS
CCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCEEEEEECCCCCEE
LVFYSGGNFPAEFQNDAFVAMRGSWNRKPASGYEIVRIRFQNGQPQRFEPFVTGFLTDDG
EEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCC
TRHIARPVGLAMLKDGSLLLSDDGNGTIFRVAYTGGAAAPTAAAVPPAQPMLAQAAKGVG
CHHHHHHHCEEEEECCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCC
VPLVLDRPETAGARGRIAVRSPAIAPQALIPERYSEYADAVSPPLAWDPVPGAQSYVLIM
CEEEEECCCCCCCCCEEEEECCCCCCHHHCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
EDPDSLPINPFVHWVAWNIPPSTTSLPEGLQEQERLTLPDGMMQGRNSRNTPGYFGPQPP
ECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCC
VGDPAHRYAFQVLALDKALDLPIGADRDQVLAAAQGHVIAKGSLVGRYRQAEKPPKSGVL
CCCHHHHHEEEEEEEHHHHCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCC
PAGVAKTVGTKMPATRR
CCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLSAILAGTCAALALSTAAYAQQGDGTDVQVAIHVFKPDKAPAIPERLAGLKTPAGFTV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHCCCCCCCEEE
TTFATGLKNPRIIAVAPNGGIYVSRREQGDVVLLKDADGNGVADGPPVVVANRPSAHGLA
EEEHHCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEE
IKDNKLYIATVKEIFVADIRPDGMLGPLQMIVGDLPDGGQHPNRTMAFGPDGMLYVSVGS
EECCEEEEEEEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECC
TCNACNESNPENASILRVSPDGKTRTIFARNLRNTIGFGWHPATGELWGMDHGIDDLGDD
CCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
QQPEELNRIEQGKQYGWPHAFGAGAIHPQTTPPGEITKAQWLAASTPMVLGYTAHAAPMS
CCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCEEEEEECCCCCEE
LVFYSGGNFPAEFQNDAFVAMRGSWNRKPASGYEIVRIRFQNGQPQRFEPFVTGFLTDDG
EEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCC
TRHIARPVGLAMLKDGSLLLSDDGNGTIFRVAYTGGAAAPTAAAVPPAQPMLAQAAKGVG
CHHHHHHHCEEEEECCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCC
VPLVLDRPETAGARGRIAVRSPAIAPQALIPERYSEYADAVSPPLAWDPVPGAQSYVLIM
CEEEEECCCCCCCCCEEEEECCCCCCHHHCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
EDPDSLPINPFVHWVAWNIPPSTTSLPEGLQEQERLTLPDGMMQGRNSRNTPGYFGPQPP
ECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCC
VGDPAHRYAFQVLALDKALDLPIGADRDQVLAAAQGHVIAKGSLVGRYRQAEKPPKSGVL
CCCHHHHHEEEEEEEHHHHCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCC
PAGVAKTVGTKMPATRR
CCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]