Click here to switch to the map view.

The map label for this gene is mprF [H]

Identifier: 148550703

GI number: 148550703

Start: 162709

End: 163035

Strand: Direct

Name: mprF [H]

Synonym: Swit_5267

Alternate gene names: 148550703

Gene position: 162709-163035 (Clockwise)

Preceding gene: 148550702

Following gene: 148550704

Centisome position: 52.45

GC content: 67.89

Gene sequence:

>327_bases
ATGCGCCACGATGCCGACATGCCCTATGGCACGATGGACTATCTGTTCGTGCGGCTGATGCAATGGGGCCATGGGCAGGG
CTATCGCTGGTTCACCCTCGGCCTCGCCCCCTTGTCCGGCCTGGAGGCGCGCCGCCTGGCGCCGCTCTGGGCGCGGCTCG
GCGCGCTTCTCTACCATCACGGCCAAGCGCTCTACGGCTTCGAGGGCCTGCGCAGCTACAAGGAGAAATTCTCGCCTGTC
TGGGAGCCGCGCTTCATCGCGGGACCGCAAGGCCCGGCGCTCGCCAGGGCGCTGTTCGACCTCCAGGCGCTGATCGGCGG
CAAATGA

Upstream 100 bases:

>100_bases
CGCCCGCTTCGACTGCGCGGTCGTCCTGCGCGAGGAGAAGATTGTCGCCTTCGCCAATATCTGGGCGACGCAGGATCGCT
CCGAGCTGTCGATCGACCTG

Downstream 100 bases:

>100_bases
GCGGCCGGTCTCCTGCACGGCGATGGGTCCGCGCCGCGCTGCTGGTCGCGCTGCTCGTCATCGCCGCGGGCGCGGGATAT
TGCCATTTTCTGGGCTATCC

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 108; Mature: 108

Protein sequence:

>108_residues
MRHDADMPYGTMDYLFVRLMQWGHGQGYRWFTLGLAPLSGLEARRLAPLWARLGALLYHHGQALYGFEGLRSYKEKFSPV
WEPRFIAGPQGPALARALFDLQALIGGK

Sequences:

>Translated_108_residues
MRHDADMPYGTMDYLFVRLMQWGHGQGYRWFTLGLAPLSGLEARRLAPLWARLGALLYHHGQALYGFEGLRSYKEKFSPV
WEPRFIAGPQGPALARALFDLQALIGGK
>Mature_108_residues
MRHDADMPYGTMDYLFVRLMQWGHGQGYRWFTLGLAPLSGLEARRLAPLWARLGALLYHHGQALYGFEGLRSYKEKFSPV
WEPRFIAGPQGPALARALFDLQALIGGK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 12249; Mature: 12249

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHDADMPYGTMDYLFVRLMQWGHGQGYRWFTLGLAPLSGLEARRLAPLWARLGALLYHH
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
GQALYGFEGLRSYKEKFSPVWEPRFIAGPQGPALARALFDLQALIGGK
CCHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHDADMPYGTMDYLFVRLMQWGHGQGYRWFTLGLAPLSGLEARRLAPLWARLGALLYHH
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
GQALYGFEGLRSYKEKFSPVWEPRFIAGPQGPALARALFDLQALIGGK
CCHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]