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The map label for this gene is galE [C]

Identifier: 148380637

GI number: 148380637

Start: 2826963

End: 2827880

Strand: Reverse

Name: galE [C]

Synonym: CBO2679

Alternate gene names: 148380637

Gene position: 2827880-2826963 (Counterclockwise)

Preceding gene: 148380638

Following gene: 148380636

Centisome position: 72.75

GC content: 27.45

Gene sequence:

>918_bases
ATGAAAATATTAGTTACTGGTGGCGCAGGATTTATAGCATCGAATTTAGTAGATAAACTTATAAGTATGGGAAATGATGT
ATGTATAATTGATAATTTATCCACTGGAAATATAAATAATGTAAATAAAAAAGCTAGATTATATATAAATGATATATTGG
ATTCTAATATAGCTAACATATTTAAAAAAGAAAAGTTTGATATAGTTTATCATTTTGCTGCTCAAATCGATGTACAAAAA
TCTATAAAAGATCCTATGTTTGATTCTAATGTAAATATATGTGGTACCGTGAATATATTAAAAAGCTGTGTTGATTATGG
AGTTAAGAAGATAATATATCCTTCTTCAGCAGCAGTTTATGGACAACCAGGGTATTTACCTATAGATGAAAAACATAGGG
TAAAACCCATATCTTCTTATGGATTATCAAAATATACACCAGAAGAATATATAAGGTCCTTTAGTGAATTATATAACTTG
GATTATACTATATTTAGATATGCTAATGTTTATGGTATAAGACAGGATCCTAAGGGTGAAGGTGGAGTAGTATCTATATT
TATGGATAGATTATTTAAAAATTATCCCCTATGCATATTCGGAGATGGAAAAGCTTTGAGAGATTATATATATGTAGAAG
ATGTGGTAAATGCTAATATTGCCGCCTTATATAATGGTAGTAGAAATCTATTTAATATAGGTACCGGTGTTTATATTACT
GTTAAAGATTTAGCTCAAATGATGATAGATACTATGAAAGTTCAATCTCATATAGAGTACCAAGAGGCTAGAAAAGGAGA
TATAGAGAAATCTTATTTTAATATAGAAAAGGCTAAAGTGGAACTTAAGTGGGAACCAAAATATAGTTTACAAAAGGGGC
TTATAAAAACTATAAATTATTATAAAAACAATATATAA

Upstream 100 bases:

>100_bases
GATAGGATATTAGGTAGACAAGCAAAAGTTAATATAGAAGAGGATACCATATTAACTTGGGAATTATTTTAATTATTATT
TTAAAAGAGGATGATTAACT

Downstream 100 bases:

>100_bases
GATAATGCTTATTTAAGGGTGTTACATAAGGTGATAAATATGTTAACAAAATTTAAAAATATATTAAAAAACAATAAATT
TAATGTGATTTTCAAATATT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKILVTGGAGFIASNLVDKLISMGNDVCIIDNLSTGNINNVNKKARLYINDILDSNIANIFKKEKFDIVYHFAAQIDVQK
SIKDPMFDSNVNICGTVNILKSCVDYGVKKIIYPSSAAVYGQPGYLPIDEKHRVKPISSYGLSKYTPEEYIRSFSELYNL
DYTIFRYANVYGIRQDPKGEGGVVSIFMDRLFKNYPLCIFGDGKALRDYIYVEDVVNANIAALYNGSRNLFNIGTGVYIT
VKDLAQMMIDTMKVQSHIEYQEARKGDIEKSYFNIEKAKVELKWEPKYSLQKGLIKTINYYKNNI

Sequences:

>Translated_305_residues
MKILVTGGAGFIASNLVDKLISMGNDVCIIDNLSTGNINNVNKKARLYINDILDSNIANIFKKEKFDIVYHFAAQIDVQK
SIKDPMFDSNVNICGTVNILKSCVDYGVKKIIYPSSAAVYGQPGYLPIDEKHRVKPISSYGLSKYTPEEYIRSFSELYNL
DYTIFRYANVYGIRQDPKGEGGVVSIFMDRLFKNYPLCIFGDGKALRDYIYVEDVVNANIAALYNGSRNLFNIGTGVYIT
VKDLAQMMIDTMKVQSHIEYQEARKGDIEKSYFNIEKAKVELKWEPKYSLQKGLIKTINYYKNNI
>Mature_305_residues
MKILVTGGAGFIASNLVDKLISMGNDVCIIDNLSTGNINNVNKKARLYINDILDSNIANIFKKEKFDIVYHFAAQIDVQK
SIKDPMFDSNVNICGTVNILKSCVDYGVKKIIYPSSAAVYGQPGYLPIDEKHRVKPISSYGLSKYTPEEYIRSFSELYNL
DYTIFRYANVYGIRQDPKGEGGVVSIFMDRLFKNYPLCIFGDGKALRDYIYVEDVVNANIAALYNGSRNLFNIGTGVYIT
VKDLAQMMIDTMKVQSHIEYQEARKGDIEKSYFNIEKAKVELKWEPKYSLQKGLIKTINYYKNNI

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=321, Percent_Identity=32.7102803738318, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=31.0650887573964, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=31.0650887573964, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=31.0650887573964, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=28.1553398058252, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI193211614, Length=248, Percent_Identity=26.2096774193548, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI8393516, Length=248, Percent_Identity=26.2096774193548, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=27.7945619335347, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790049, Length=274, Percent_Identity=31.3868613138686, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=28.2352941176471, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=26.5671641791045, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788589, Length=339, Percent_Identity=22.7138643067847, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788365, Length=328, Percent_Identity=20.7317073170732, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788366, Length=276, Percent_Identity=23.1884057971014, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=27.741935483871, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=28.9855072463768, Blast_Score=123, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=28.8184438040346, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17568069, Length=323, Percent_Identity=28.4829721362229, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI115532424, Length=322, Percent_Identity=27.9503105590062, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319493, Length=328, Percent_Identity=32.3170731707317, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=29.126213592233, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=28.6135693215339, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34625; Mature: 34625

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVTGGAGFIASNLVDKLISMGNDVCIIDNLSTGNINNVNKKARLYINDILDSNIANI
CEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHEEEEHHHHHHHHHHH
FKKEKFDIVYHFAAQIDVQKSIKDPMFDSNVNICGTVNILKSCVDYGVKKIIYPSSAAVY
HHHHCHHEEEEEHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCHHEEECCCCCEEC
GQPGYLPIDEKHRVKPISSYGLSKYTPEEYIRSFSELYNLDYTIFRYANVYGIRQDPKGE
CCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHEEEECCCCCCC
GGVVSIFMDRLFKNYPLCIFGDGKALRDYIYVEDVVNANIAALYNGSRNLFNIGTGVYIT
CCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEE
VKDLAQMMIDTMKVQSHIEYQEARKGDIEKSYFNIEKAKVELKWEPKYSLQKGLIKTINY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEEEEEEECCCHHHHHHHHHHHHH
YKNNI
HHCCC
>Mature Secondary Structure
MKILVTGGAGFIASNLVDKLISMGNDVCIIDNLSTGNINNVNKKARLYINDILDSNIANI
CEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHEEEEHHHHHHHHHHH
FKKEKFDIVYHFAAQIDVQKSIKDPMFDSNVNICGTVNILKSCVDYGVKKIIYPSSAAVY
HHHHCHHEEEEEHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCHHEEECCCCCEEC
GQPGYLPIDEKHRVKPISSYGLSKYTPEEYIRSFSELYNLDYTIFRYANVYGIRQDPKGE
CCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHEEEECCCCCCC
GGVVSIFMDRLFKNYPLCIFGDGKALRDYIYVEDVVNANIAALYNGSRNLFNIGTGVYIT
CCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEE
VKDLAQMMIDTMKVQSHIEYQEARKGDIEKSYFNIEKAKVELKWEPKYSLQKGLIKTINY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEEEEEEECCCHHHHHHHHHHHHH
YKNNI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]