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The map label for this gene is mtn [H]

Identifier: 148379443

GI number: 148379443

Start: 1602743

End: 1603435

Strand: Direct

Name: mtn [H]

Synonym: CBO1471

Alternate gene names: 148379443

Gene position: 1602743-1603435 (Clockwise)

Preceding gene: 148379442

Following gene: 148379444

Centisome position: 41.23

GC content: 31.6

Gene sequence:

>693_bases
ATGACAATAGGTATTATAGGTGCAATGGATGAGGAATTAGAATTATTATTAAAGGAATTAGATTTGGAAAAAAAACAAGT
TAAAGCCAATATGACATTTAATTTTGGGAAACTTTGGGGAAATAATGTGGTAGCTGTAAGATGCGGTATAGGCAAAGTAA
ATGCAGCAGTTTGTGCTCAGATACTCATAGATGATTTTAAAGTGGATAGAATAATAAATGTAGGTATAGCTGGGGGAACA
GCAGAAAATGTATTACCAGGAGATGTTGTAGTAGCGGATAGTTTAGTTCAGCATGATATGGATACTTCTGCTTTTGGAGA
TCCAATAGGACAAATTCCAAGATTAGATACATTTGATTTTAAATGTGACATTGAATTAATAGAGAAAGCTAAAAAGGCCT
TCCAGAATAAAACAGAACATAAATGTTTAGTAGGAAGAATAGTTACAGGAGATCAATTCATAAATGATAAAAAAAGGGTT
CAATGGATGTGCAAAGAGTTTAATGCACTAGCTTGTGAAATGGAGGGTGGAAGTATAGCTCAGGTCTCTTATTTAAATAA
TATTCCTTTTGTGGTTATAAGATCCATATCAGATAATGCAAGTACAGGAGCTCATATGGAATATGAAGATTTTATGACTA
TAGCTATAAAAAATTCTACTAACATATTAAAAGGAATGCTTACAAATATATAA

Upstream 100 bases:

>100_bases
TTTACTAGAGGAAGTAGGTAAAGTAAAGGTAAAAGTAGAAGTAGAAGAAAATGAGATTATTAAAGCTATAAAAGAAAGTA
TAGATAGGGAGGAAAAATAA

Downstream 100 bases:

>100_bases
ATTTATCAGATATTTAGTTATTTAAAAGTTTAAAATAATATATAAAATACTTTAATAGTATATAAAAACATTAGTCTAAA
GAAGAGAGAAAAGAAAGAAA

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTIGIIGAMDEELELLLKELDLEKKQVKANMTFNFGKLWGNNVVAVRCGIGKVNAAVCAQILIDDFKVDRIINVGIAGGT
AENVLPGDVVVADSLVQHDMDTSAFGDPIGQIPRLDTFDFKCDIELIEKAKKAFQNKTEHKCLVGRIVTGDQFINDKKRV
QWMCKEFNALACEMEGGSIAQVSYLNNIPFVVIRSISDNASTGAHMEYEDFMTIAIKNSTNILKGMLTNI

Sequences:

>Translated_230_residues
MTIGIIGAMDEELELLLKELDLEKKQVKANMTFNFGKLWGNNVVAVRCGIGKVNAAVCAQILIDDFKVDRIINVGIAGGT
AENVLPGDVVVADSLVQHDMDTSAFGDPIGQIPRLDTFDFKCDIELIEKAKKAFQNKTEHKCLVGRIVTGDQFINDKKRV
QWMCKEFNALACEMEGGSIAQVSYLNNIPFVVIRSISDNASTGAHMEYEDFMTIAIKNSTNILKGMLTNI
>Mature_229_residues
TIGIIGAMDEELELLLKELDLEKKQVKANMTFNFGKLWGNNVVAVRCGIGKVNAAVCAQILIDDFKVDRIINVGIAGGTA
ENVLPGDVVVADSLVQHDMDTSAFGDPIGQIPRLDTFDFKCDIELIEKAKKAFQNKTEHKCLVGRIVTGDQFINDKKRVQ
WMCKEFNALACEMEGGSIAQVSYLNNIPFVVIRSISDNASTGAHMEYEDFMTIAIKNSTNILKGMLTNI

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=231, Percent_Identity=37.2294372294372, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25320; Mature: 25188

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGIIGAMDEELELLLKELDLEKKQVKANMTFNFGKLWGNNVVAVRCGIGKVNAAVCAQ
CEEEEEECCCHHHHHHHHHHCCCHHHEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHH
ILIDDFKVDRIINVGIAGGTAENVLPGDVVVADSLVQHDMDTSAFGDPIGQIPRLDTFDF
HHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCC
KCDIELIEKAKKAFQNKTEHKCLVGRIVTGDQFINDKKRVQWMCKEFNALACEMEGGSIA
EECHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHCHHHHHHHHHHHCCEEEEEECCCCEE
QVSYLNNIPFVVIRSISDNASTGAHMEYEDFMTIAIKNSTNILKGMLTNI
EEEECCCCCEEEEEECCCCCCCCCCEEHHHEEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
TIGIIGAMDEELELLLKELDLEKKQVKANMTFNFGKLWGNNVVAVRCGIGKVNAAVCAQ
EEEEEECCCHHHHHHHHHHCCCHHHEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHH
ILIDDFKVDRIINVGIAGGTAENVLPGDVVVADSLVQHDMDTSAFGDPIGQIPRLDTFDF
HHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCC
KCDIELIEKAKKAFQNKTEHKCLVGRIVTGDQFINDKKRVQWMCKEFNALACEMEGGSIA
EECHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHCHHHHHHHHHHHCCEEEEEECCCCEE
QVSYLNNIPFVVIRSISDNASTGAHMEYEDFMTIAIKNSTNILKGMLTNI
EEEECCCCCEEEEEECCCCCCCCCCEEHHHEEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA