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The map label for this gene is spoVD [H]

Identifier: 148379428

GI number: 148379428

Start: 1587887

End: 1590067

Strand: Direct

Name: spoVD [H]

Synonym: CBO1456

Alternate gene names: 148379428

Gene position: 1587887-1590067 (Clockwise)

Preceding gene: 148379427

Following gene: 148379429

Centisome position: 40.85

GC content: 33.06

Gene sequence:

>2181_bases
TTGTCAAATAGTAAGTACAGAGACAAAGTAATAATTAGAAAAAGAATGATGTTTATATTTGCTCTTCTAATTTTAGCTTT
TATAGGTTTAGTAATAAAAATGGGAACTATAATGATAGGTCAGTCTCCAGAGTTGAAAAAAAAAGCTGTGGATCAATGGA
CAAGTGAAGTAAAAATTGATGCTAAAAGAGGTAGAATATTAGACAGAAATGGTAATGAACTAGCAGTAAGTGCTAATGTA
TACAGAGTAGATTTAGATATGAATACTTTAAGAAGTACCATGGAAGAAAAAAAACTATCTAAAAATGACGTAGCATCAAA
ACTTTCAAAAGCATTAGATATGGAACAAAAAGAAGTAGAAAAAGTATTGAATAAAAAGCTTCCAAGTGGATTACCTTTAG
CCTCTGCTACTTTAAAAAGAAGAATAGAAAAGGACAAGGCTGACAAAGTAAGAGATTTAGATTTAAGAGGGATTTTAGTA
TCTGCGGACACTAAAAGATACTATCCTAATAATAATTTTTTATCTCATGTATTAGGACATACAAATTCTGATGGAAAGGG
ACTTACAGGAGTAGAGTTATACTATAACAATATATTATCAGGTAAGCCAGGAGTAAGGATTGCTGAAACGGATAATAAAA
GCAAGGAATTACCTTATACCATTTCAGAATACACTAAACCAGAGGATGGGAAAGATTTAGTATTAACCATAGATGAAATG
ATACAACACTTTAGTGAGAAAACAGCAGAGCAAGCTTTAAAGGATAATAAAGCAAAGGCAGTATCTGTAGTAGTAATGGA
TCCTAGAACTGGAGAAGTACTAGCTATGGCAAATAAGCCAGATTATAATCCTAATGATCCTTGGCAGGAAGGGAAAAGCT
ATGAAGAACTTCAACAAAACTGGAGAAATAGATCGGTTAATGATACTTTTGAACCAGGATCTGTATTTAAAGTTTTTACA
GCAGCTACCGCTTTAGAGGAAAATTTAATAACCTCCGAGGATAAGTTTACTTGTGGTGGAAGCATAACTATAGGGAAAAG
AACTATACGTTGCTGGAAAAGCGGAGGGCATGGTACTCAAAATTTTATAGAAATACTTAAAAACTCTTGTAACGTAGGTT
TTGCACAGTTAGGTCATAAGATAGGTAAAGAAAAATTAAATTCATATATTCAAAAATTTGGTTTTGGTAAAAAAACTGGT
ATAGATCTTCCAGGAGAAGCTCCAGGGATAACAAAGAAAACGGAAAATATATCAGATATAGATTTAGCTACAATATCCTT
TGGTCAAGCTAACACGTTGTCTATAGTACAATATCTCCAAGCTTTTAATGCAGTGGCTAATGGAGGAAATCTTATAAAAC
CTCATGTTATGAAAGAAGTAGGACATTTTGATGAGGAAAAAAATAAAGAAATAATAGAAAAGAAAAATACCATAGAAAGC
AAGCAAATTTTAAATAGTCAAAAGATGGCTACCCTAAGAAGCTACTTAGAAAAAGTAGTGTCAGAAGGGGGCGGTAAGAA
GGCTTATATAGCAGGTTATCATATAGGTGGCAAAACTGGTACAGCTCAAAAGGCTGGTAAGGGTGGATATATGCCTGGTA
AATATGTAGCTTCCTTTGCAGGAATGGCACCAGCTGATAATCCAAGAATAACAGTATTTGTTTCTATTGATGAACCGGAT
CCTTCAAATTACTATGCAGGCCAAATAGCAGCTCCAGCAGCACAGGGGCTATTCAAAGATATATTTAATTATTTGGCATT
AAAAAGTGATGCCCAAGGGGAAGATATAGCTAAAAGTCTTCTAAAGGATATAACTATTCCTGAAGTTAGAGGTAAGTCAA
AAGAAGAAGCACAAAAAATATTAAAAGATTTAAAATTAGATTGTGAGATACAATCTGAGGGAGAATATATAGTAGATATG
AATCCTAAACCAGGGTATACTGTAAAAGAAGGCAGTAAAATTGTTCTTTACACAGGGAACAGTCAAAATTATAATAAAGT
AGTAGTTGTTCCGAATGTAAAAGGGTATACAGTAGAACAGGCCATGTCTGTATTAAATAGTATAGGCTTAAGAGGGGATA
TACAGGGTGATGGAATTATTTCTCATCAAAGTATAGAAGCAAATAAGGAAGTTAAAAAAGGAACTATGGTTAACTTAAAA
GCAGAACCAATAGGAGATTAA

Upstream 100 bases:

>100_bases
AGCAGAAAATTCTAAAAATCACATTGGAGAAAAGCATAATGCTTTTTTAGAGTTTTTTTCTAATTTAAAGAAAGTGCTAT
TTTAAATGGAGGTAACATAA

Downstream 100 bases:

>100_bases
TATAATAAAAAATTGGCATGCAGTAATACAGGGTTCTGTGTATTGCATGCTAATATTTTGTTAGTTCTACATAGATAATT
TAGTTAATAGACTTTAAAAA

Product: stage V sporulation protein D

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSNSKYRDKVIIRKRMMFIFALLILAFIGLVIKMGTIMIGQSPELKKKAVDQWTSEVKIDAKRGRILDRNGNELAVSANV
YRVDLDMNTLRSTMEEKKLSKNDVASKLSKALDMEQKEVEKVLNKKLPSGLPLASATLKRRIEKDKADKVRDLDLRGILV
SADTKRYYPNNNFLSHVLGHTNSDGKGLTGVELYYNNILSGKPGVRIAETDNKSKELPYTISEYTKPEDGKDLVLTIDEM
IQHFSEKTAEQALKDNKAKAVSVVVMDPRTGEVLAMANKPDYNPNDPWQEGKSYEELQQNWRNRSVNDTFEPGSVFKVFT
AATALEENLITSEDKFTCGGSITIGKRTIRCWKSGGHGTQNFIEILKNSCNVGFAQLGHKIGKEKLNSYIQKFGFGKKTG
IDLPGEAPGITKKTENISDIDLATISFGQANTLSIVQYLQAFNAVANGGNLIKPHVMKEVGHFDEEKNKEIIEKKNTIES
KQILNSQKMATLRSYLEKVVSEGGGKKAYIAGYHIGGKTGTAQKAGKGGYMPGKYVASFAGMAPADNPRITVFVSIDEPD
PSNYYAGQIAAPAAQGLFKDIFNYLALKSDAQGEDIAKSLLKDITIPEVRGKSKEEAQKILKDLKLDCEIQSEGEYIVDM
NPKPGYTVKEGSKIVLYTGNSQNYNKVVVVPNVKGYTVEQAMSVLNSIGLRGDIQGDGIISHQSIEANKEVKKGTMVNLK
AEPIGD

Sequences:

>Translated_726_residues
MSNSKYRDKVIIRKRMMFIFALLILAFIGLVIKMGTIMIGQSPELKKKAVDQWTSEVKIDAKRGRILDRNGNELAVSANV
YRVDLDMNTLRSTMEEKKLSKNDVASKLSKALDMEQKEVEKVLNKKLPSGLPLASATLKRRIEKDKADKVRDLDLRGILV
SADTKRYYPNNNFLSHVLGHTNSDGKGLTGVELYYNNILSGKPGVRIAETDNKSKELPYTISEYTKPEDGKDLVLTIDEM
IQHFSEKTAEQALKDNKAKAVSVVVMDPRTGEVLAMANKPDYNPNDPWQEGKSYEELQQNWRNRSVNDTFEPGSVFKVFT
AATALEENLITSEDKFTCGGSITIGKRTIRCWKSGGHGTQNFIEILKNSCNVGFAQLGHKIGKEKLNSYIQKFGFGKKTG
IDLPGEAPGITKKTENISDIDLATISFGQANTLSIVQYLQAFNAVANGGNLIKPHVMKEVGHFDEEKNKEIIEKKNTIES
KQILNSQKMATLRSYLEKVVSEGGGKKAYIAGYHIGGKTGTAQKAGKGGYMPGKYVASFAGMAPADNPRITVFVSIDEPD
PSNYYAGQIAAPAAQGLFKDIFNYLALKSDAQGEDIAKSLLKDITIPEVRGKSKEEAQKILKDLKLDCEIQSEGEYIVDM
NPKPGYTVKEGSKIVLYTGNSQNYNKVVVVPNVKGYTVEQAMSVLNSIGLRGDIQGDGIISHQSIEANKEVKKGTMVNLK
AEPIGD
>Mature_725_residues
SNSKYRDKVIIRKRMMFIFALLILAFIGLVIKMGTIMIGQSPELKKKAVDQWTSEVKIDAKRGRILDRNGNELAVSANVY
RVDLDMNTLRSTMEEKKLSKNDVASKLSKALDMEQKEVEKVLNKKLPSGLPLASATLKRRIEKDKADKVRDLDLRGILVS
ADTKRYYPNNNFLSHVLGHTNSDGKGLTGVELYYNNILSGKPGVRIAETDNKSKELPYTISEYTKPEDGKDLVLTIDEMI
QHFSEKTAEQALKDNKAKAVSVVVMDPRTGEVLAMANKPDYNPNDPWQEGKSYEELQQNWRNRSVNDTFEPGSVFKVFTA
ATALEENLITSEDKFTCGGSITIGKRTIRCWKSGGHGTQNFIEILKNSCNVGFAQLGHKIGKEKLNSYIQKFGFGKKTGI
DLPGEAPGITKKTENISDIDLATISFGQANTLSIVQYLQAFNAVANGGNLIKPHVMKEVGHFDEEKNKEIIEKKNTIESK
QILNSQKMATLRSYLEKVVSEGGGKKAYIAGYHIGGKTGTAQKAGKGGYMPGKYVASFAGMAPADNPRITVFVSIDEPDP
SNYYAGQIAAPAAQGLFKDIFNYLALKSDAQGEDIAKSLLKDITIPEVRGKSKEEAQKILKDLKLDCEIQSEGEYIVDMN
PKPGYTVKEGSKIVLYTGNSQNYNKVVVVPNVKGYTVEQAMSVLNSIGLRGDIQGDGIISHQSIEANKEVKKGTMVNLKA
EPIGD

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=591, Percent_Identity=29.6108291032149, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1786854, Length=659, Percent_Identity=24.2792109256449, Blast_Score=149, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 80080; Mature: 79948

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSKYRDKVIIRKRMMFIFALLILAFIGLVIKMGTIMIGQSPELKKKAVDQWTSEVKID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHEEEE
AKRGRILDRNGNELAVSANVYRVDLDMNTLRSTMEEKKLSKNDVASKLSKALDMEQKEVE
CCCCEEECCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
KVLNKKLPSGLPLASATLKRRIEKDKADKVRDLDLRGILVSADTKRYYPNNNFLSHVLGH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHCC
TNSDGKGLTGVELYYNNILSGKPGVRIAETDNKSKELPYTISEYTKPEDGKDLVLTIDEM
CCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEHHHCCCCCCCCEEEEEHHHH
IQHFSEKTAEQALKDNKAKAVSVVVMDPRTGEVLAMANKPDYNPNDPWQEGKSYEELQQN
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCHHCCCCHHHHHHH
WRNRSVNDTFEPGSVFKVFTAATALEENLITSEDKFTCGGSITIGKRTIRCWKSGGHGTQ
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCEEEECHHHHHHCCCCCCCHH
NFIEILKNSCNVGFAQLGHKIGKEKLNSYIQKFGFGKKTGIDLPGEAPGITKKTENISDI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DLATISFGQANTLSIVQYLQAFNAVANGGNLIKPHVMKEVGHFDEEKNKEIIEKKNTIES
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
KQILNSQKMATLRSYLEKVVSEGGGKKAYIAGYHIGGKTGTAQKAGKGGYMPGKYVASFA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
GMAPADNPRITVFVSIDEPDPSNYYAGQIAAPAAQGLFKDIFNYLALKSDAQGEDIAKSL
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKDITIPEVRGKSKEEAQKILKDLKLDCEIQSEGEYIVDMNPKPGYTVKEGSKIVLYTGN
HHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEECCCCEEEEEECC
SQNYNKVVVVPNVKGYTVEQAMSVLNSIGLRGDIQGDGIISHQSIEANKEVKKGTMVNLK
CCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHCCCCEEEEE
AEPIGD
CCCCCC
>Mature Secondary Structure 
SNSKYRDKVIIRKRMMFIFALLILAFIGLVIKMGTIMIGQSPELKKKAVDQWTSEVKID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHEEEE
AKRGRILDRNGNELAVSANVYRVDLDMNTLRSTMEEKKLSKNDVASKLSKALDMEQKEVE
CCCCEEECCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
KVLNKKLPSGLPLASATLKRRIEKDKADKVRDLDLRGILVSADTKRYYPNNNFLSHVLGH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHCC
TNSDGKGLTGVELYYNNILSGKPGVRIAETDNKSKELPYTISEYTKPEDGKDLVLTIDEM
CCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEHHHCCCCCCCCEEEEEHHHH
IQHFSEKTAEQALKDNKAKAVSVVVMDPRTGEVLAMANKPDYNPNDPWQEGKSYEELQQN
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCHHCCCCHHHHHHH
WRNRSVNDTFEPGSVFKVFTAATALEENLITSEDKFTCGGSITIGKRTIRCWKSGGHGTQ
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCEEEECHHHHHHCCCCCCCHH
NFIEILKNSCNVGFAQLGHKIGKEKLNSYIQKFGFGKKTGIDLPGEAPGITKKTENISDI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DLATISFGQANTLSIVQYLQAFNAVANGGNLIKPHVMKEVGHFDEEKNKEIIEKKNTIES
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
KQILNSQKMATLRSYLEKVVSEGGGKKAYIAGYHIGGKTGTAQKAGKGGYMPGKYVASFA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
GMAPADNPRITVFVSIDEPDPSNYYAGQIAAPAAQGLFKDIFNYLALKSDAQGEDIAKSL
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKDITIPEVRGKSKEEAQKILKDLKLDCEIQSEGEYIVDMNPKPGYTVKEGSKIVLYTGN
HHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEECCCCEEEEEECC
SQNYNKVVVVPNVKGYTVEQAMSVLNSIGLRGDIQGDGIISHQSIEANKEVKKGTMVNLK
CCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHCCCCEEEEE
AEPIGD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]