Click here to switch to the map view.

The map label for this gene is grdD [H]

Identifier: 148379247

GI number: 148379247

Start: 1378511

End: 1379677

Strand: Direct

Name: grdD [H]

Synonym: CBO1264

Alternate gene names: 148379247

Gene position: 1378511-1379677 (Clockwise)

Preceding gene: 148379246

Following gene: 148379248

Centisome position: 35.47

GC content: 32.05

Gene sequence:

>1167_bases
ATGGATAATAAAGAAGTGAATAAAATAATAGGAAAAACTCTTCTTGATATTGCAGAATCTATAGAAAAGGGAGACTTTAG
TAGAAAGATAGTAGTAGGAATTACTACTTTAGGTAGTGAACATGGAGTTGAAAATTTAGTAAAAGGTGCTGAAGTGGCTG
CTAAAAAACATAATGACATAAAGGTAGTTTTAATAGGACCTAAAGTGGATACAGAATTAGAAATAGTAGAAGCTAATGAA
GAAGATAAAATGTATAACAAAATGGAAGAATTATTAGATACAAAATATATAGATGCAGCAGTTACTATGCATTACAATTT
TCCTATAGGGGTATCAACTGTAGGAAAGGTAGTTACCCCAGCTGATGGGAAAGAGATGTTTTTAGCTACAACTACAGGAA
CAGCTTCTATGAATAGAACAGAAGCTATGATTAAAAATGCAGTATATGGAATAATAACAGCTAAAACTATGGGGATAAAA
GAGCCTAATGTAGGGATTTTAAATTTAGATGGAGCAAGACAAGTAGAGAAAGCATTAAAAGAATTAGATAAAAATGGTTA
TAAAATAAATTTTGCTAATTCTCTAAGAGCAGATGGTGGTTCAGTAATGAGAGGAAATGATCTTTTAAAAGGAACACCGG
ATGTTATGGTGACAGATACTCTTACAGGAAATCTTTTAATGAAAGTATTTTCTTCTTATACTACTGGAGGAAGTTATGAA
GGATTTGGCTATGGCTACGGACCAGGTATAGGAGAGGATTATGAAAGAAATATCCTAATTCTATCTAGGGCTTCAGGTGT
ACCAGTGGTAGCTAATGCTATAGAATATGCAAAGGATCTAGTTAAAGGTAATATAAATAAATTAATAAAAGAAGAGTTTA
AAAAGGCTAATGAGGCTAAATTAAAGGATATATTAAGCTCTATAGAAAACAAAGAAGACAAAAAAATAAAAGATGAAGAA
GAAGTTCCAATGCCTACAAAGGAAATAGCTACAGCATCTATTAGTGGGATAGATGTAATGGATATAGAGGATGCTCAAAA
AACCCTTTGGAAAGAAGGTATATATGCAGAGGGCGGTATGGGATGCACAGGTCCTGTCATAAAAGTAAATGATAAAAATT
ACGATAAGGCTGCAGAAATATTAACTGAAAAAGGTTTTATAGCTTAA

Upstream 100 bases:

>100_bases
GGAAAAAGGAATTTCTGAGGATAAAGTGAGAAAAATAATTGCAGAATCCATAAAAAAATTAGCATCACAGCTAGTAGAAG
AATAAGGGGTGATGTATAGT

Downstream 100 bases:

>100_bases
AAATAAACTATAAATATATTTGTGAAAATTAAAGTGAATAAGTTTATTTATAAAATTTTAAAGGTGAATATGGTATTAAA
ATAAAAAAGTCCATTTACAT

Product: glycine reductase complex component C, alpha subunit

Products: NA

Alternate protein names: Protein PC alpha [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MDNKEVNKIIGKTLLDIAESIEKGDFSRKIVVGITTLGSEHGVENLVKGAEVAAKKHNDIKVVLIGPKVDTELEIVEANE
EDKMYNKMEELLDTKYIDAAVTMHYNFPIGVSTVGKVVTPADGKEMFLATTTGTASMNRTEAMIKNAVYGIITAKTMGIK
EPNVGILNLDGARQVEKALKELDKNGYKINFANSLRADGGSVMRGNDLLKGTPDVMVTDTLTGNLLMKVFSSYTTGGSYE
GFGYGYGPGIGEDYERNILILSRASGVPVVANAIEYAKDLVKGNINKLIKEEFKKANEAKLKDILSSIENKEDKKIKDEE
EVPMPTKEIATASISGIDVMDIEDAQKTLWKEGIYAEGGMGCTGPVIKVNDKNYDKAAEILTEKGFIA

Sequences:

>Translated_388_residues
MDNKEVNKIIGKTLLDIAESIEKGDFSRKIVVGITTLGSEHGVENLVKGAEVAAKKHNDIKVVLIGPKVDTELEIVEANE
EDKMYNKMEELLDTKYIDAAVTMHYNFPIGVSTVGKVVTPADGKEMFLATTTGTASMNRTEAMIKNAVYGIITAKTMGIK
EPNVGILNLDGARQVEKALKELDKNGYKINFANSLRADGGSVMRGNDLLKGTPDVMVTDTLTGNLLMKVFSSYTTGGSYE
GFGYGYGPGIGEDYERNILILSRASGVPVVANAIEYAKDLVKGNINKLIKEEFKKANEAKLKDILSSIENKEDKKIKDEE
EVPMPTKEIATASISGIDVMDIEDAQKTLWKEGIYAEGGMGCTGPVIKVNDKNYDKAAEILTEKGFIA
>Mature_388_residues
MDNKEVNKIIGKTLLDIAESIEKGDFSRKIVVGITTLGSEHGVENLVKGAEVAAKKHNDIKVVLIGPKVDTELEIVEANE
EDKMYNKMEELLDTKYIDAAVTMHYNFPIGVSTVGKVVTPADGKEMFLATTTGTASMNRTEAMIKNAVYGIITAKTMGIK
EPNVGILNLDGARQVEKALKELDKNGYKINFANSLRADGGSVMRGNDLLKGTPDVMVTDTLTGNLLMKVFSSYTTGGSYE
GFGYGYGPGIGEDYERNILILSRASGVPVVANAIEYAKDLVKGNINKLIKEEFKKANEAKLKDILSSIENKEDKKIKDEE
EVPMPTKEIATASISGIDVMDIEDAQKTLWKEGIYAEGGMGCTGPVIKVNDKNYDKAAEILTEKGFIA

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003664
- InterPro:   IPR012116 [H]

Pfam domain/function: PF02504 FA_synthesis [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 42150; Mature: 42150

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKEVNKIIGKTLLDIAESIEKGDFSRKIVVGITTLGSEHGVENLVKGAEVAAKKHNDI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCE
KVVLIGPKVDTELEIVEANEEDKMYNKMEELLDTKYIDAAVTMHYNFPIGVSTVGKVVTP
EEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHCCEECC
ADGKEMFLATTTGTASMNRTEAMIKNAVYGIITAKTMGIKEPNVGILNLDGARQVEKALK
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCEEEECCCHHHHHHHHH
ELDKNGYKINFANSLRADGGSVMRGNDLLKGTPDVMVTDTLTGNLLMKVFSSYTTGGSYE
HHCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCC
GFGYGYGPGIGEDYERNILILSRASGVPVVANAIEYAKDLVKGNINKLIKEEFKKANEAK
CCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHH
LKDILSSIENKEDKKIKDEEEVPMPTKEIATASISGIDVMDIEDAQKTLWKEGIYAEGGM
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCC
GCTGPVIKVNDKNYDKAAEILTEKGFIA
CCCCCEEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDNKEVNKIIGKTLLDIAESIEKGDFSRKIVVGITTLGSEHGVENLVKGAEVAAKKHNDI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCE
KVVLIGPKVDTELEIVEANEEDKMYNKMEELLDTKYIDAAVTMHYNFPIGVSTVGKVVTP
EEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHCCEECC
ADGKEMFLATTTGTASMNRTEAMIKNAVYGIITAKTMGIKEPNVGILNLDGARQVEKALK
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCEEEECCCHHHHHHHHH
ELDKNGYKINFANSLRADGGSVMRGNDLLKGTPDVMVTDTLTGNLLMKVFSSYTTGGSYE
HHCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCC
GFGYGYGPGIGEDYERNILILSRASGVPVVANAIEYAKDLVKGNINKLIKEEFKKANEAK
CCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHH
LKDILSSIENKEDKKIKDEEEVPMPTKEIATASISGIDVMDIEDAQKTLWKEGIYAEGGM
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCC
GCTGPVIKVNDKNYDKAAEILTEKGFIA
CCCCCEEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11737196; 1587286 [H]