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The map label for this gene is trxA [H]

Identifier: 148379244

GI number: 148379244

Start: 1375980

End: 1376300

Strand: Direct

Name: trxA [H]

Synonym: CBO1260

Alternate gene names: 148379244

Gene position: 1375980-1376300 (Clockwise)

Preceding gene: 148379243

Following gene: 148379245

Centisome position: 35.4

GC content: 30.22

Gene sequence:

>321_bases
ATGTTAGTAGTTGATAAGAAAACTTTTGAAGACGAGGTATTAAAATCAGATGGTTATACGTTAGTAGATTATTTTGGGGA
TGGTTGTGTTCCATGTGAGGCTTTAATGCCTGATGTGGAGGAATTATCACAAAAATATGAAGATAAGGTTAAATTCTGCA
AATTAAATACTTCTAAGGCTAGAAGACTTGCTATATCTCAAAAAGTTTTAGGGCTTCCAACTATAATCTTATATAAGGAT
GGAGAAAAATTAGAAGAAGTAGTTAAAGATGATGCTACAAAAGAAAATATAGAAGCTATGATAAAAAAACACACACTATA
A

Upstream 100 bases:

>100_bases
TACTGCAGCGGCAGATGGTGCTATAGCAGCAGTAGAAGCTTATAAATATGTTGAAGATACTTTTTAAATATAAAAAATTT
ATTTGAAAGGCGGTTATAAA

Downstream 100 bases:

>100_bases
AATTTTAAAGATTATTTAGTCATTTAAAGTGTGTATATAAATATCAAGGAATTTAAAATATAAATAAATTAAGGGAGGAA
TTTTAATGAGTCTATTTGAA

Product: thioredoxin family protein

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MLVVDKKTFEDEVLKSDGYTLVDYFGDGCVPCEALMPDVEELSQKYEDKVKFCKLNTSKARRLAISQKVLGLPTIILYKD
GEKLEEVVKDDATKENIEAMIKKHTL

Sequences:

>Translated_106_residues
MLVVDKKTFEDEVLKSDGYTLVDYFGDGCVPCEALMPDVEELSQKYEDKVKFCKLNTSKARRLAISQKVLGLPTIILYKD
GEKLEEVVKDDATKENIEAMIKKHTL
>Mature_106_residues
MLVVDKKTFEDEVLKSDGYTLVDYFGDGCVPCEALMPDVEELSQKYEDKVKFCKLNTSKARRLAISQKVLGLPTIILYKD
GEKLEEVVKDDATKENIEAMIKKHTL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=75, Percent_Identity=36, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12045; Mature: 12045

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVDKKTFEDEVLKSDGYTLVDYFGDGCVPCEALMPDVEELSQKYEDKVKFCKLNTSKA
CEEECCCCHHHHHHHCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHH
RRLAISQKVLGLPTIILYKDGEKLEEVVKDDATKENIEAMIKKHTL
HHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLVVDKKTFEDEVLKSDGYTLVDYFGDGCVPCEALMPDVEELSQKYEDKVKFCKLNTSKA
CEEECCCCHHHHHHHCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHH
RRLAISQKVLGLPTIILYKDGEKLEEVVKDDATKENIEAMIKKHTL
HHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8223622; 1995593 [H]