BacMap

Definition	Clostridium botulinum A str. ATCC 3502, complete genome.
Accession	NC_009495
Length	3,886,916

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The map label for this gene is yhcG [H]

Identifier: 148379189

GI number: 148379189

Start: 1327256

End: 1328128

Strand: Direct

Name: yhcG [H]

Synonym: CBO1206

Alternate gene names: 148379189

Gene position: 1327256-1328128 (Clockwise)

Preceding gene: 148379188

Following gene: 148379190

Centisome position: 34.15

GC content: 26.12

Gene sequence:

>873_bases
ATGAGTAATATAGTAATAAAAAATGTTACTAAATCATACCAAAGAAAAGAAGCGTTATCAAATATTTCTATTAACATAGA
AGAAGGAAAAATATATGGTCTTCTTGGGAGAAATGGAGCAGGAAAAACAACTCTGCTGCATCTTATAACTAATAGAGCCA
TTTTAGATAGTGGAGAAATCTTAATAGATGGTGAAAATGTTTATGAAAATAACAAGGCCCTTTCTAAAGTTTATTTTATG
GAAGAAAAAAATCTTTTTCCTGAATCAATGAAAATAGTAGATGTTTTTGAATGGACAAAAGAGTTTTATGAAGACTTTGA
TATGGAATATGCTATTAAACTTAGTGAGCTTTTTAAATTAAATATAAAGAAAAAAGTAAAAAGTTTATCAACAGGATATA
AATCAATAAGTAAAATTATTGCTACTTTAGCTTCAGGAGCAGAAATTTTAATTTTTGATGAACCTATTTTAGGCTTAGAT
GCTAACCATAGGGAACTTTTTTATAAAGAGCTATTAAAGATTTATGGAGAAGGGAAAAAAACAATTGTAATATCCACCCA
CATAATAGAGGAAATATCTCATCTTTTAGAAAAAGTAGTTATACTAAAGGAAGGTAAAATAATAGAAAGTGATTCTGTTG
AAAATATGCTTAATTTAGCCTATGCAGTTTCAGGTAGTAGTGATGATGTAGATAAATATATAACCGCTAAAAACATAATA
AATATAGAAACTTTAGGCTCATATAAAAAAGCTACAATTTTACAAGAAAGAACTAAAGAAGATTTAGATAATATAAAGAA
ACTAGAATTAGAAATTAGCACAGTAGAACTTCAAAAACTATTTATATATTTAACAAATATGGAGGAAAAATAG

Upstream 100 bases:

>100_bases
AAATTTTTTGATAGCTACATTTTAAGTCTTGTGGATGAAGCTAAACGACTAGGAATAACTATAGATGAAATAATGGATAT
GATAAAAGGGGGATATGGCA

Downstream 100 bases:

>100_bases
ATGGAAAAAAGTAATAAAATTTGCAAATATCAATTAAAGACTTCTATAAAACCTATATTGATTTATTATAGTATATTAAT
AGGATTCTTATTATTAATAT

Product: ABC transporter, ATP-binding protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSNIVIKNVTKSYQRKEALSNISINIEEGKIYGLLGRNGAGKTTLLHLITNRAILDSGEILIDGENVYENNKALSKVYFM
EEKNLFPESMKIVDVFEWTKEFYEDFDMEYAIKLSELFKLNIKKKVKSLSTGYKSISKIIATLASGAEILIFDEPILGLD
ANHRELFYKELLKIYGEGKKTIVISTHIIEEISHLLEKVVILKEGKIIESDSVENMLNLAYAVSGSSDDVDKYITAKNII
NIETLGSYKKATILQERTKEDLDNIKKLELEISTVELQKLFIYLTNMEEK

Sequences:

>Translated_290_residues
MSNIVIKNVTKSYQRKEALSNISINIEEGKIYGLLGRNGAGKTTLLHLITNRAILDSGEILIDGENVYENNKALSKVYFM
EEKNLFPESMKIVDVFEWTKEFYEDFDMEYAIKLSELFKLNIKKKVKSLSTGYKSISKIIATLASGAEILIFDEPILGLD
ANHRELFYKELLKIYGEGKKTIVISTHIIEEISHLLEKVVILKEGKIIESDSVENMLNLAYAVSGSSDDVDKYITAKNII
NIETLGSYKKATILQERTKEDLDNIKKLELEISTVELQKLFIYLTNMEEK
>Mature_289_residues
SNIVIKNVTKSYQRKEALSNISINIEEGKIYGLLGRNGAGKTTLLHLITNRAILDSGEILIDGENVYENNKALSKVYFME
EKNLFPESMKIVDVFEWTKEFYEDFDMEYAIKLSELFKLNIKKKVKSLSTGYKSISKIIATLASGAEILIFDEPILGLDA
NHRELFYKELLKIYGEGKKTIVISTHIIEEISHLLEKVVILKEGKIIESDSVENMLNLAYAVSGSSDDVDKYITAKNIIN
IETLGSYKKATILQERTKEDLDNIKKLELEISTVELQKLFIYLTNMEEK

Specific function: Part Of The Abc Transporter Complex Cysawtp Involved In Sulfate/Thiosulfate Import. Responsible For Energy Coupling To The Transport System. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=214, Percent_Identity=28.9719626168224, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI30795238, Length=214, Percent_Identity=28.9719626168224, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI27477115, Length=214, Percent_Identity=24.2990654205607, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI31657092, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI21536376, Length=240, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI45446740, Length=212, Percent_Identity=27.3584905660377, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI47078218, Length=212, Percent_Identity=27.3584905660377, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI27436953, Length=218, Percent_Identity=23.8532110091743, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI153792144, Length=221, Percent_Identity=23.9819004524887, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI116734710, Length=226, Percent_Identity=26.9911504424779, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI105990541, Length=212, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI6005701, Length=209, Percent_Identity=24.4019138755981, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI27262624, Length=241, Percent_Identity=21.5767634854772, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27262626, Length=241, Percent_Identity=21.5767634854772, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI11967969, Length=308, Percent_Identity=24.6753246753247, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9955968, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9955966, Length=229, Percent_Identity=25.3275109170306, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI45243524, Length=229, Percent_Identity=25.3275109170306, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788761, Length=223, Percent_Identity=30.9417040358744, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081791, Length=210, Percent_Identity=28.0952380952381, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788450, Length=232, Percent_Identity=27.1551724137931, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48995001, Length=216, Percent_Identity=26.3888888888889, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790739, Length=226, Percent_Identity=23.0088495575221, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790190, Length=223, Percent_Identity=26.457399103139, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994943, Length=227, Percent_Identity=23.7885462555066, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788210, Length=218, Percent_Identity=24.7706422018349, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788225, Length=235, Percent_Identity=25.1063829787234, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=25, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081782, Length=221, Percent_Identity=25.7918552036199, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081709, Length=231, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789586, Length=234, Percent_Identity=24.3589743589744, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787792, Length=243, Percent_Identity=25.5144032921811, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787712, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=27.8538812785388, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=213, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790467, Length=227, Percent_Identity=24.6696035242291, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790162, Length=261, Percent_Identity=25.6704980842912, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786345, Length=229, Percent_Identity=24.4541484716157, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788472, Length=232, Percent_Identity=25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789891, Length=216, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788540, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789593, Length=228, Percent_Identity=24.5614035087719, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789672, Length=226, Percent_Identity=23.8938053097345, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788897, Length=217, Percent_Identity=23.0414746543779, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789032, Length=216, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=214, Percent_Identity=22.4299065420561, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=221, Percent_Identity=24.8868778280543, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787143, Length=225, Percent_Identity=25.7777777777778, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790525, Length=260, Percent_Identity=22.3076923076923, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787112, Length=231, Percent_Identity=26.8398268398268, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=228, Percent_Identity=28.0701754385965, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=221, Percent_Identity=29.8642533936652, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=221, Percent_Identity=29.8642533936652, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=221, Percent_Identity=29.8642533936652, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=201, Percent_Identity=26.3681592039801, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=241, Percent_Identity=25.7261410788382, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17552010, Length=215, Percent_Identity=28.3720930232558, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=224, Percent_Identity=25.4464285714286, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=214, Percent_Identity=29.9065420560748, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322177, Length=202, Percent_Identity=26.2376237623762, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324585, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650853, Length=235, Percent_Identity=28.5106382978723, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24650855, Length=235, Percent_Identity=29.3617021276596, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281362751, Length=241, Percent_Identity=28.6307053941909, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24582014, Length=227, Percent_Identity=28.6343612334802, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582012, Length=227, Percent_Identity=28.6343612334802, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221500365, Length=224, Percent_Identity=27.6785714285714, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007184, Length=224, Percent_Identity=27.6785714285714, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666092, Length=248, Percent_Identity=29.8387096774194, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI85725262, Length=266, Percent_Identity=27.8195488721804, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221512771, Length=211, Percent_Identity=30.3317535545024, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643674, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007328, Length=215, Percent_Identity=29.7674418604651, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574150, Length=215, Percent_Identity=29.7674418604651, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571209, Length=213, Percent_Identity=24.8826291079812, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573571, Length=211, Percent_Identity=24.6445497630332, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581407, Length=229, Percent_Identity=24.8908296943231, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573573, Length=211, Percent_Identity=24.6445497630332, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 33036; Mature: 32904

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIVIKNVTKSYQRKEALSNISINIEEGKIYGLLGRNGAGKTTLLHLITNRAILDSGEI
CCCEEEHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHCCEEECCCCE
LIDGENVYENNKALSKVYFMEEKNLFPESMKIVDVFEWTKEFYEDFDMEYAIKLSELFKL
EECCCCCCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHH
NIKKKVKSLSTGYKSISKIIATLASGAEILIFDEPILGLDANHRELFYKELLKIYGEGKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCHHHHHHHHHHHHHCCCCE
TIVISTHIIEEISHLLEKVVILKEGKIIESDSVENMLNLAYAVSGSSDDVDKYITAKNII
EEEEEHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHEECCCCCCHHHHHHHHHEE
NIETLGSYKKATILQERTKEDLDNIKKLELEISTVELQKLFIYLTNMEEK
EEHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHEEHHEEEECCCCC
>Mature Secondary Structure 
SNIVIKNVTKSYQRKEALSNISINIEEGKIYGLLGRNGAGKTTLLHLITNRAILDSGEI
CCEEEHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHCCEEECCCCE
LIDGENVYENNKALSKVYFMEEKNLFPESMKIVDVFEWTKEFYEDFDMEYAIKLSELFKL
EECCCCCCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHH
NIKKKVKSLSTGYKSISKIIATLASGAEILIFDEPILGLDANHRELFYKELLKIYGEGKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCHHHHHHHHHHHHHCCCCE
TIVISTHIIEEISHLLEKVVILKEGKIIESDSVENMLNLAYAVSGSSDDVDKYITAKNII
EEEEEHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHEECCCCCCHHHHHHHHHEE
NIETLGSYKKATILQERTKEDLDNIKKLELEISTVELQKLFIYLTNMEEK
EEHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHEEHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]