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The map label for this gene is fchA [H]

Identifier: 148379157

GI number: 148379157

Start: 1286555

End: 1287187

Strand: Direct

Name: fchA [H]

Synonym: CBO1171

Alternate gene names: 148379157

Gene position: 1286555-1287187 (Clockwise)

Preceding gene: 148379156

Following gene: 148379158

Centisome position: 33.1

GC content: 30.96

Gene sequence:

>633_bases
GTGTTAGATAAAAGTTGTAAAGAATTTATAGATATTTTATCCTCTAAGGAACCTGTACCAGGTGGAGGCGGTGCTTGTGC
TTATGTAGGAGCTTTAGGTATGGCCTTAGGCAATATGGTAGCAAATCTTACTATGGGGAAGAAAAAATATAAAGATGTAG
AAGAGGATGTAAAAGAAATATTGGAAGAAGGAGAAATCTTAATACAGAAATTAGAGGAATTAGTAAATAAAGATGCTGAA
GTATTTTATCCATTATCTAAAGCTTATGGATTACCTAAAAATACAGAAGAGGAAAAAGCATATAAAGATAAAATTATGGA
GGAGGCATTATATAACGCTAGTCTAGTGCCGCTAGAAATAGCTAAATGTGCAGCAGAGACCATAGATCTTCATTATAAAT
TAGCTAGAATAGGAACTAGAATTGCTATAAGTGATGTAGGTGTAGGAGTGCTATTTTGTAAAACAGCACTAGAAGCTTCC
AAGTTAAATGTATATATAAATACTGGTATGATGAAAAATAATGATATAAAAAATTCTTTGGAAGAAGAAATCAACACCTT
AGTTTCTAAATATTCAACTAAGGCAGATAAAGTTTATAGTTATGTAGAAAATTTAATAAGGGGAAATGAATAA

Upstream 100 bases:

>100_bases
AAAAATAATGTATAATATATATTAGTATTATAGAAAGTGTAATTAATTTAGCATAGTATTTACTATAATAAGAATAAATT
AATAAGGTAGGTGGATTTTT

Downstream 100 bases:

>100_bases
TGGCTAAAATATTATATGGAAATGAAGTAGCTTTAAAAATAAAGGAAGATTTAAATTTAAGAATAGATAAATTAAAAGAA
AAAAATATAATACCTAAGTT

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTMGKKKYKDVEEDVKEILEEGEILIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEIAKCAAETIDLHYKLARIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLEEEINTLVSKYSTKADKVYSYVENLIRGNE

Sequences:

>Translated_210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTMGKKKYKDVEEDVKEILEEGEILIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEIAKCAAETIDLHYKLARIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLEEEINTLVSKYSTKADKVYSYVENLIRGNE
>Mature_210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTMGKKKYKDVEEDVKEILEEGEILIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEIAKCAAETIDLHYKLARIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLEEEINTLVSKYSTKADKVYSYVENLIRGNE

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=167, Percent_Identity=27.5449101796407, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI11140815, Length=167, Percent_Identity=27.5449101796407, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 23190; Mature: 23190

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTMGKKKYKDVEEDVKEI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LEEGEILIQKLEELVNKDAEVFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEI
HHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AKCAAETIDLHYKLARIGTRIAISDVGVGVLFCKTALEASKLNVYINTGMMKNNDIKNSL
HHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH
EEEINTLVSKYSTKADKVYSYVENLIRGNE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTMGKKKYKDVEEDVKEI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LEEGEILIQKLEELVNKDAEVFYPLSKAYGLPKNTEEEKAYKDKIMEEALYNASLVPLEI
HHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AKCAAETIDLHYKLARIGTRIAISDVGVGVLFCKTALEASKLNVYINTGMMKNNDIKNSL
HHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH
EEEINTLVSKYSTKADKVYSYVENLIRGNE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]