Click here to switch to the map view.

The map label for this gene is glpT [H]

Identifier: 148379061

GI number: 148379061

Start: 1180573

End: 1181910

Strand: Direct

Name: glpT [H]

Synonym: CBO1071

Alternate gene names: 148379061

Gene position: 1180573-1181910 (Clockwise)

Preceding gene: 148379060

Following gene: 148379062

Centisome position: 30.37

GC content: 32.44

Gene sequence:

>1338_bases
ATGTTAAAGGACTTATTTAAACCGGCTTCTCACATAGAAAGAATGCCAAAGGAAAAAATTGATTCGGCTTATAGGCGGTA
TCGTATACAGGTATTTATAAGTATTTATGTAGGATATCTAACTTATTATTTTGTAAGAAGTAATTTTTCTTTGGCAAAGG
TTTACTTAATACAAGAAGGTTTTACTAAGACTCAATTAGGTTTTGTAGCTTCAGCTCTTGGTCTTGCTTATGGAGTAAGT
AAATTTGTAATGGGAAACTTATCAGATAGATCTAATCCTAGATATTTTTTAGCAGCAGGATTAATTCTATCTGGTATTGT
AAACCTATTCTTTCCTATGACTAAAAGTATCACAGCAATGTTTGCATTAATGCTTTTAAATGGATGGTTTCAAGGTATGG
GATGGCCACCTTGTGGAAGAACTATGACTCATTGGTTCTCAGACAAAGAGCGTGGAGTAAAAATGTCAATATGGAATACA
GCTCATAACGTAGGTGGAGGTTTTATTGCCACAGTAGTTTTAATAGGAGTATCTATATTTGGAAGTTGGAAGGGAGCTTT
TTATCTACCAGCCGTAATAGCTATTGTAGTAGGAATTTTATTTATATTATTTGCAAAGGATACACCTCAATCAGTGGGGC
TTCCACCAATAGAAGAATACAAAAATGATTATCCAGAAATTCAAGTAGAGGATAGAGAAAAAGAATTATCAGGAAAAGAA
ATATTATTTAAATATGTTTTAAATAATAAATATTTATGGTATATAGCTATAGCAAATATTTTTGTATATCTTGTTAGATA
TGGGGTTATAAATTGGGTACCTACATACTTAAAAGAAGTTAAACATTTTAATCCTAAAGATTCATCTTTAGCTTTTGCTT
TGTTTGAATATGCAGCAATACCAGGAACCATATTTGTTGGATGGTTAAGTGATAAAGTCTTTAACGGAAGACGTGCACCT
GTCGGAGTATTTTGTATGATAGGTGTAACTATAGCAACTTATGTATATTGGAAAAGCAATAGTATATTAGCAATAAATTG
TGCCCTATCTTCTATAGGAGCTTTAATATATGGACCAGTTATGTTAATAGGCGTAAGTGCTTTAGATTTAGTTCCTAAAA
AAGCAGCAGGTACGGCAGCAGGCTTTACAGGTTTATTTGGATATATGGGGGGACAAGTATTAGCAGAAGTAGCAATGGGA
GCAGTTGTTGATAAATTTAGTTGGAATGGAGGGTTTATTTTATTAATGATATCCTCTGTATTAGCTATAGTATTTTTATC
TTTTACTTGGAATACCCATGATAGATCAGAAAAAGGGCCTGATAAAGTAGCAGTTTAA

Upstream 100 bases:

>100_bases
TGTAAAAATTAAATATCAATAAGGATAGCTAATATAATATTAGCTATCCTTATTGACGGTTAATAAATATTGACAATAAA
AGGAAAGAGGGAATGACATA

Downstream 100 bases:

>100_bases
AAATAGAATATATTTTTAAAACTTGACAAAAATAATAAATAAAGCATATAATAGATTATAAATTTTAAAGTAAAATATTT
ATATTCATTGATGAGAAGAG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEGFTKTQLGFVASALGLAYGVS
KFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAMFALMLLNGWFQGMGWPPCGRTMTHWFSDKERGVKMSIWNT
AHNVGGGFIATVVLIGVSIFGSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAIPGTIFVGWLSDKVFNGRRAP
VGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPVMLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMG
AVVDKFSWNGGFILLMISSVLAIVFLSFTWNTHDRSEKGPDKVAV

Sequences:

>Translated_445_residues
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEGFTKTQLGFVASALGLAYGVS
KFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAMFALMLLNGWFQGMGWPPCGRTMTHWFSDKERGVKMSIWNT
AHNVGGGFIATVVLIGVSIFGSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAIPGTIFVGWLSDKVFNGRRAP
VGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPVMLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMG
AVVDKFSWNGGFILLMISSVLAIVFLSFTWNTHDRSEKGPDKVAV
>Mature_445_residues
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEGFTKTQLGFVASALGLAYGVS
KFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAMFALMLLNGWFQGMGWPPCGRTMTHWFSDKERGVKMSIWNT
AHNVGGGFIATVVLIGVSIFGSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAIPGTIFVGWLSDKVFNGRRAP
VGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPVMLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMG
AVVDKFSWNGGFILLMISSVLAIVFLSFTWNTHDRSEKGPDKVAV

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=402, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4503847, Length=402, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI256219483, Length=402, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI256219543, Length=424, Percent_Identity=29.0094339622642, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI256219564, Length=333, Percent_Identity=27.3273273273273, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI38093649, Length=398, Percent_Identity=26.8844221105528, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI223717983, Length=398, Percent_Identity=26.8844221105528, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI49619231, Length=406, Percent_Identity=22.6600985221675, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI46361976, Length=397, Percent_Identity=23.9294710327456, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788573, Length=430, Percent_Identity=57.2093023255814, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI87082310, Length=433, Percent_Identity=36.7205542725173, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI2367259, Length=446, Percent_Identity=32.7354260089686, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI2367379, Length=345, Percent_Identity=24.3478260869565, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082320, Length=358, Percent_Identity=22.9050279329609, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789515, Length=450, Percent_Identity=22.6666666666667, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789152, Length=455, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=380, Percent_Identity=26.8421052631579, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564202, Length=443, Percent_Identity=25.9593679458239, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133901854, Length=475, Percent_Identity=22.3157894736842, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI133901856, Length=480, Percent_Identity=22.5, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17542316, Length=492, Percent_Identity=23.5772357723577, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71991453, Length=454, Percent_Identity=21.1453744493392, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=454, Percent_Identity=21.1453744493392, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540458, Length=284, Percent_Identity=22.887323943662, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24656861, Length=485, Percent_Identity=21.6494845360825, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24656866, Length=485, Percent_Identity=21.6494845360825, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550478, Length=485, Percent_Identity=21.6494845360825, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49433; Mature: 49433

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEG
CCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
FTKTQLGFVASALGLAYGVSKFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FALMLLNGWFQGMGWPPCGRTMTHWFSDKERGVKMSIWNTAHNVGGGFIATVVLIGVSIF
HHHHHHHHHHHCCCCCCCCCHHHHHHCCHHCCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
GSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCHHHCCHHH
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAI
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
PGTIFVGWLSDKVFNGRRAPVGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPV
CCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHH
MLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMGAVVDKFSWNGGFILLMISSV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LAIVFLSFTWNTHDRSEKGPDKVAV
HHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEG
CCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
FTKTQLGFVASALGLAYGVSKFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FALMLLNGWFQGMGWPPCGRTMTHWFSDKERGVKMSIWNTAHNVGGGFIATVVLIGVSIF
HHHHHHHHHHHCCCCCCCCCHHHHHHCCHHCCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
GSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCHHHCCHHH
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAI
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
PGTIFVGWLSDKVFNGRRAPVGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPV
CCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHH
MLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMGAVVDKFSWNGGFILLMISSV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LAIVFLSFTWNTHDRSEKGPDKVAV
HHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]