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The map label for this gene is panC [H]

Identifier: 148378427

GI number: 148378427

Start: 505634

End: 506479

Strand: Reverse

Name: panC [H]

Synonym: CBO0424

Alternate gene names: 148378427

Gene position: 506479-505634 (Counterclockwise)

Preceding gene: 148378428

Following gene: 148378426

Centisome position: 13.03

GC content: 27.3

Gene sequence:

>846_bases
ATGAATATAGTTAATACAATAAAAGATGTTAGATTAATCATAAAAAAATGGAAAGATGAAAATTTATCTATAGGCTATGT
ACCTACTATGGGATATTTGCATGAAGGTCATGCCTCTCTTATAAAAAAAGCTAGAGAAGAAAATGATAAAATTATAGTTT
CAATTTTTGTAAATCCAATTCAATTTGGACCAAAGGAAGACTACTCTACTTACCCTAGAGATTTAGTTAAAGATTCATCC
TTATGTGAAAAATTTGGAGTAGATTTAATTTTTAATCCTGAAACCTCAGAAATGTATCCTAATAAAATATATAGCCATAT
AAATGTGGACATACTTACAGAAAAATTATGTGGAGAAAAAAGACCTGGCCATTTTCAAGGGGTATGCACAGTTTTAACAA
AATTTTTTAATATACTAAACCCTACAAAGGCTTATTTTGGTGAAAAAGACGCTCAGCAATTAGCTGTAGTAAGAAAGATG
GTAGAGGATTTAAATTTTCCTATAGAAATAATAGGTTGTCCTATAATTAGAGAAGAAGATGGTTTAGCTAAAAGCTCAAG
AAATGCTTATTTAAATAAGCAGGAAAGAAAATCTGCCTTAATATTAAATAAAAGTTTAAAAGAAGCTCTAAAGGCACTAG
AATCTGGAGAAAAAAATTTAAATAATATAAAAGATATTATAGTAAGTAAGCTAAATAAAGAGCCTCTAGCTAAAATAGAT
TATGTAAGTATAGTAGATAGCATCACTTTACAATCTGTGGAAAAAATACAATCTTCAATATTAGTAGCTATAGCAGTTTA
TATAGGTAAAACAAGACTTATAGACAATTTTACTTTTAAACTATAA

Upstream 100 bases:

>100_bases
AACATGCTTTTAAAATAGATGATGATGTAATAAATAAATTATATTAGTTTTTAAATAACCAGCAGAGGGGGGTAAAGGCT
GATTTTCTCAGCTGAACAAT

Downstream 100 bases:

>100_bases
CTACTCTTTACTCCCTCTTTTAAGGTGATGCAAATATTAGAGCGAGTAGTCATCGGATAAATATTTTTTGAACGCTAATC
TATTATTAATAATAAATACG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNIVNTIKDVRLIIKKWKDENLSIGYVPTMGYLHEGHASLIKKAREENDKIIVSIFVNPIQFGPKEDYSTYPRDLVKDSS
LCEKFGVDLIFNPETSEMYPNKIYSHINVDILTEKLCGEKRPGHFQGVCTVLTKFFNILNPTKAYFGEKDAQQLAVVRKM
VEDLNFPIEIIGCPIIREEDGLAKSSRNAYLNKQERKSALILNKSLKEALKALESGEKNLNNIKDIIVSKLNKEPLAKID
YVSIVDSITLQSVEKIQSSILVAIAVYIGKTRLIDNFTFKL

Sequences:

>Translated_281_residues
MNIVNTIKDVRLIIKKWKDENLSIGYVPTMGYLHEGHASLIKKAREENDKIIVSIFVNPIQFGPKEDYSTYPRDLVKDSS
LCEKFGVDLIFNPETSEMYPNKIYSHINVDILTEKLCGEKRPGHFQGVCTVLTKFFNILNPTKAYFGEKDAQQLAVVRKM
VEDLNFPIEIIGCPIIREEDGLAKSSRNAYLNKQERKSALILNKSLKEALKALESGEKNLNNIKDIIVSKLNKEPLAKID
YVSIVDSITLQSVEKIQSSILVAIAVYIGKTRLIDNFTFKL
>Mature_281_residues
MNIVNTIKDVRLIIKKWKDENLSIGYVPTMGYLHEGHASLIKKAREENDKIIVSIFVNPIQFGPKEDYSTYPRDLVKDSS
LCEKFGVDLIFNPETSEMYPNKIYSHINVDILTEKLCGEKRPGHFQGVCTVLTKFFNILNPTKAYFGEKDAQQLAVVRKM
VEDLNFPIEIIGCPIIREEDGLAKSSRNAYLNKQERKSALILNKSLKEALKALESGEKNLNNIKDIIVSKLNKEPLAKID
YVSIVDSITLQSVEKIQSSILVAIAVYIGKTRLIDNFTFKL

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=283, Percent_Identity=43.4628975265018, Blast_Score=238, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6322046, Length=311, Percent_Identity=38.2636655948553, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31883; Mature: 31883

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVNTIKDVRLIIKKWKDENLSIGYVPTMGYLHEGHASLIKKAREENDKIIVSIFVNPI
CCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
QFGPKEDYSTYPRDLVKDSSLCEKFGVDLIFNPETSEMYPNKIYSHINVDILTEKLCGEK
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCHHHHHHHHCCCC
RPGHFQGVCTVLTKFFNILNPTKAYFGEKDAQQLAVVRKMVEDLNFPIEIIGCPIIREED
CCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCEEECCC
GLAKSSRNAYLNKQERKSALILNKSLKEALKALESGEKNLNNIKDIIVSKLNKEPLAKID
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHH
YVSIVDSITLQSVEKIQSSILVAIAVYIGKTRLIDNFTFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MNIVNTIKDVRLIIKKWKDENLSIGYVPTMGYLHEGHASLIKKAREENDKIIVSIFVNPI
CCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
QFGPKEDYSTYPRDLVKDSSLCEKFGVDLIFNPETSEMYPNKIYSHINVDILTEKLCGEK
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCHHHHHHHHCCCC
RPGHFQGVCTVLTKFFNILNPTKAYFGEKDAQQLAVVRKMVEDLNFPIEIIGCPIIREED
CCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCEEECCC
GLAKSSRNAYLNKQERKSALILNKSLKEALKALESGEKNLNNIKDIIVSKLNKEPLAKID
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHH
YVSIVDSITLQSVEKIQSSILVAIAVYIGKTRLIDNFTFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA