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The map label for this gene is queC [H]

Identifier: 148361198

GI number: 148361198

Start: 3434338

End: 3435024

Strand: Reverse

Name: queC [H]

Synonym: LPC_3172

Alternate gene names: 148361198

Gene position: 3435024-3434338 (Counterclockwise)

Preceding gene: 148361206

Following gene: 148361197

Centisome position: 96.05

GC content: 43.09

Gene sequence:

>687_bases
ATGAAAAAAGCTGTGGTCTTGCTTTCTGGCGGTTTGGATTCAACGACTTGTCTCGCGTTGGCTAAGTCTCAGGGGTTTGC
TTGTTATGCATTAAGCTTTTCTTACGGCCAGAGGCATTCCGCAGAACTGTGTGCCGCAACTCGAATAGCGAAACATATGG
ATGCGGCTGATCATAAAATAGTCACCCTGGATACTGCTTTATTTGGTGGCTCCGCTTTGACTGATGCATCTATTGAGGTA
CCCGAATTCAAGGAAAGCCCGGAAATACCAGTCACCTATGTCCCAGCCCGTAATACTATTTTTTTGGCTATGGCTTTGGG
TTATGCTGAATCAATTGGTGCCAGAGATATTTTTATTGGTGCCAGTTCTGTTGATTATTCTCATTATCCTGATTGTCGCC
CGGAGTTTATTGAATCTTTCCAATCTTTGGCAAACTTGGCAACGAAAGCAGGAATTGAAGGCGATCGCTTTACTATCAAT
GCTCCTCTGCAATATCTGAGCAAAGTGCAGACTATTCAATTAGGTACTGAACTTGGTGTTGATTACGGATTAACGGTTTC
CTGCTATCAAGCGAATGAAGCAGGTGAAGCTTGCGGACAGTGTGATAGCTGTACTTTTAGAAAGCGGGGTTTTAAGAGTG
CTGGAGTAAATGATCCCACTCGATATCAAAAATGTGTTCATATTTAA

Upstream 100 bases:

>100_bases
GGTGTCGTCATCACATTCCATATTGTGGCATAATTGACCCGCATTTTAGCAGGAATTTTTAAGAGCAAGCAATTGTTCCA
ATTTTTTGAGGTTTTGCATT

Downstream 100 bases:

>100_bases
CCCACACAGTTAAATTAATGATATAATCCCTGAAATTTTGGTTTGGAGTTTTTTATGTGGGATAAAATCAAAGAATGGTA
TAAAAATAACAAGAGCTATT

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMDAADHKIVTLDTALFGGSALTDASIEV
PEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTIN
APLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVNDPTRYQKCVHI

Sequences:

>Translated_228_residues
MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMDAADHKIVTLDTALFGGSALTDASIEV
PEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTIN
APLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVNDPTRYQKCVHI
>Mature_228_residues
MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMDAADHKIVTLDTALFGGSALTDASIEV
PEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTIN
APLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVNDPTRYQKCVHI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=37.4449339207048, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24522; Mature: 24522

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMDAADHKI
CCCEEEEEECCCCCHHHEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEE
VTLDTALFGGSALTDASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIG
EEEEEEHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHHHHHCCCCEEEEE
ASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTINAPLQYLSKVQTIQLGTELGV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHEEEHHHHCC
DYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVNDPTRYQKCVHI
CCCCEEEEEECCCHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMDAADHKI
CCCEEEEEECCCCCHHHEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEE
VTLDTALFGGSALTDASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIG
EEEEEEHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHHHHHCCCCEEEEE
ASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTINAPLQYLSKVQTIQLGTELGV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHEEEHHHHCC
DYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVNDPTRYQKCVHI
CCCCEEEEEECCCHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA