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The map label for this gene is hetI [H]

Identifier: 148360564

GI number: 148360564

Start: 966187

End: 966924

Strand: Reverse

Name: hetI [H]

Synonym: LPC_2508

Alternate gene names: 148360564

Gene position: 966924-966187 (Counterclockwise)

Preceding gene: 148360558

Following gene: 148360565

Centisome position: 27.04

GC content: 40.11

Gene sequence:

>738_bases
ATGATAATTACAGGATTTACTCCATTAAACACACAAAACTGCATTTTAAATGAGTCACGTATTGATCTTTGGCAGTTCTC
ATTAGACTATGAATTGCATAGTGCGTATCAGTTATTGAATGCCGATGAACGCTCCCGTGCTGATCGCTTTTATTTTAATC
GCCATAAAAGACGCTTTACCAACGCCAGAGCAACTTTAAGAATTATCCTGGCCCGATACCTTAATACGCCCCCTGAACGA
TTGGAATTTACTTACAATGCACATGGCAAGCCCAATGTGATTAATTCGCAAAAATTGCAATTTAATATCAGTCATACTGG
TGAAATGGCCATATTGGCAGTGGGTAAAACCTATCCGATTGGAGTGGATATTGAAAGATATTCAGCCCGGCCTTATGAAG
GGATTGGTAAAAATTTGTTTTCCGAGCAAGAATACCAGGAACTGAAAAAAGCACATCAGTCCCTTAAGCCAGCCTTATTT
TTTCATATATGGGCTCAAAAGGAAGCGTTCATCAAAGCGAGTGGTTTAGGTCTCTCCTATCCAACCAAAGAATTTCATGT
CCCTACCAGTTTCCCAACAAAACAATTGGTCGACGATCCCTTGCATAACATGACCTGGCAACTACGCTCATTCATGCCGG
AAGTATGCTGCAGTGGCGCTTTATGCTATCACCCTTCTGTTAGAGAAATTCGTCATGGGATCGTCCAGCTTCAACAAAAT
ATTAGTTTAAAATTTTAA

Upstream 100 bases:

>100_bases
CCAAAAATTGTCGGGTCATTGATTACTCTTTGGTGAATTAAACATCTTTGGTATATGATACTCTTAACCGTTAATCGATG
CCAGATTTCAGATACAACAG

Downstream 100 bases:

>100_bases
ATCATGTTTCAATTTAATACTTCTCAACATACGTTAATGCAAATACTGGGCGATGGGGCATGTCATAGTGGGAGTGAATT
AGGAAACGCTTTAAAAATCA

Product: phosphopantetheine-protein transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIITGFTPLNTQNCILNESRIDLWQFSLDYELHSAYQLLNADERSRADRFYFNRHKRRFTNARATLRIILARYLNTPPER
LEFTYNAHGKPNVINSQKLQFNISHTGEMAILAVGKTYPIGVDIERYSARPYEGIGKNLFSEQEYQELKKAHQSLKPALF
FHIWAQKEAFIKASGLGLSYPTKEFHVPTSFPTKQLVDDPLHNMTWQLRSFMPEVCCSGALCYHPSVREIRHGIVQLQQN
ISLKF

Sequences:

>Translated_245_residues
MIITGFTPLNTQNCILNESRIDLWQFSLDYELHSAYQLLNADERSRADRFYFNRHKRRFTNARATLRIILARYLNTPPER
LEFTYNAHGKPNVINSQKLQFNISHTGEMAILAVGKTYPIGVDIERYSARPYEGIGKNLFSEQEYQELKKAHQSLKPALF
FHIWAQKEAFIKASGLGLSYPTKEFHVPTSFPTKQLVDDPLHNMTWQLRSFMPEVCCSGALCYHPSVREIRHGIVQLQQN
ISLKF
>Mature_245_residues
MIITGFTPLNTQNCILNESRIDLWQFSLDYELHSAYQLLNADERSRADRFYFNRHKRRFTNARATLRIILARYLNTPPER
LEFTYNAHGKPNVINSQKLQFNISHTGEMAILAVGKTYPIGVDIERYSARPYEGIGKNLFSEQEYQELKKAHQSLKPALF
FHIWAQKEAFIKASGLGLSYPTKEFHVPTSFPTKQLVDDPLHNMTWQLRSFMPEVCCSGALCYHPSVREIRHGIVQLQQN
ISLKF

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 28468; Mature: 28468

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITGFTPLNTQNCILNESRIDLWQFSLDYELHSAYQLLNADERSRADRFYFNRHKRRFT
CEEECCCCCCCCCEEEECCCCEEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NARATLRIILARYLNTPPERLEFTYNAHGKPNVINSQKLQFNISHTGEMAILAVGKTYPI
HHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCC
GVDIERYSARPYEGIGKNLFSEQEYQELKKAHQSLKPALFFHIWAQKEAFIKASGLGLSY
CCCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCC
PTKEFHVPTSFPTKQLVDDPLHNMTWQLRSFMPEVCCSGALCYHPSVREIRHGIVQLQQN
CCCCEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHC
ISLKF
CCCCC
>Mature Secondary Structure
MIITGFTPLNTQNCILNESRIDLWQFSLDYELHSAYQLLNADERSRADRFYFNRHKRRFT
CEEECCCCCCCCCEEEECCCCEEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NARATLRIILARYLNTPPERLEFTYNAHGKPNVINSQKLQFNISHTGEMAILAVGKTYPI
HHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCC
GVDIERYSARPYEGIGKNLFSEQEYQELKKAHQSLKPALFFHIWAQKEAFIKASGLGLSY
CCCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCC
PTKEFHVPTSFPTKQLVDDPLHNMTWQLRSFMPEVCCSGALCYHPSVREIRHGIVQLQQN
CCCCEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHC
ISLKF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]