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The map label for this gene is kdsC [H]

Identifier: 148360515

GI number: 148360515

Start: 1022768

End: 1023295

Strand: Reverse

Name: kdsC [H]

Synonym: LPC_2456

Alternate gene names: 148360515

Gene position: 1023295-1022768 (Counterclockwise)

Preceding gene: 148360514

Following gene: 148360516

Centisome position: 28.61

GC content: 39.96

Gene sequence:

>528_bases
ATGAACGAACTATTGGAAAAAGCGAAAAAAATTAAATGTCTTATTTGTGATGTAGACGGGGTGCTCAGTGATGGCTTACT
TCACATTGATAATCACGGCAATGAGCTGAAATCATTCCATGTACAAGATGGAATGGGATTAAAATTATTAATGGCCGCCG
GGATACAAGTTGCAATCATTACCACAGCACAAAATGCTGTAGTTGACCATCGAATGGAGCAATTAGGGATAACTCATTAC
TATAAAGGTCAAGTTGATAAGCGTAGCGCTTACCAACATCTAAAAAAAACATTGGGACTCAATGATGAGGAGTTTGCCTA
TATTGGCGATGATTTGCCAGATTTACCCTTGATACAACAAGTGGGATTAGGAGTTGCAGTCAGTAATGCTGTACCGCAAG
TTCTGGAATTTGCTGATTGGAGAACAGAGCGGACTGGTGGTAGAGGCGCGGTTCGCGAATTATGTGACTTAATTCTTAAC
GCACAAAATAAAGCAGAATTGGCGATCACAGGCTATTTAAAACAATGA

Upstream 100 bases:

>100_bases
ATCACATCCTTGGTAGTAGTTGAAAATGATAATAGACCTTATGCGGTACTCCATTTACATGACTTGCTAAAAGCGGGTGT
TTTTTAATACAGAGATAGAA

Downstream 100 bases:

>100_bases
ATATTACCAAGCAAGCAATTTGGCTATTCTTGACCTTGCTTATTTTAGCAGGATCTGGTTGGTATTATGCTCATTTTAAT
CAGGCTATTATCAATAAGAA

Product: HAD superfamily transporter hydrolase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MNELLEKAKKIKCLICDVDGVLSDGLLHIDNHGNELKSFHVQDGMGLKLLMAAGIQVAIITTAQNAVVDHRMEQLGITHY
YKGQVDKRSAYQHLKKTLGLNDEEFAYIGDDLPDLPLIQQVGLGVAVSNAVPQVLEFADWRTERTGGRGAVRELCDLILN
AQNKAELAITGYLKQ

Sequences:

>Translated_175_residues
MNELLEKAKKIKCLICDVDGVLSDGLLHIDNHGNELKSFHVQDGMGLKLLMAAGIQVAIITTAQNAVVDHRMEQLGITHY
YKGQVDKRSAYQHLKKTLGLNDEEFAYIGDDLPDLPLIQQVGLGVAVSNAVPQVLEFADWRTERTGGRGAVRELCDLILN
AQNKAELAITGYLKQ
>Mature_175_residues
MNELLEKAKKIKCLICDVDGVLSDGLLHIDNHGNELKSFHVQDGMGLKLLMAAGIQVAIITTAQNAVVDHRMEQLGITHY
YKGQVDKRSAYQHLKKTLGLNDEEFAYIGDDLPDLPLIQQVGLGVAVSNAVPQVLEFADWRTERTGGRGAVRELCDLILN
AQNKAELAITGYLKQ

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=154, Percent_Identity=31.1688311688312, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI2367202, Length=162, Percent_Identity=49.3827160493827, Blast_Score=160, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19279; Mature: 19279

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELLEKAKKIKCLICDVDGVLSDGLLHIDNHGNELKSFHVQDGMGLKLLMAAGIQVAII
CHHHHHHHHHCEEEEECCCCHHCCCEEEECCCCCHHHEEECCCCCCHHHHHHCCCEEEEE
TTAQNAVVDHRMEQLGITHYYKGQVDKRSAYQHLKKTLGLNDEEFAYIGDDLPDLPLIQQ
ECCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHH
VGLGVAVSNAVPQVLEFADWRTERTGGRGAVRELCDLILNAQNKAELAITGYLKQ
HCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure
MNELLEKAKKIKCLICDVDGVLSDGLLHIDNHGNELKSFHVQDGMGLKLLMAAGIQVAII
CHHHHHHHHHCEEEEECCCCHHCCCEEEECCCCCHHHEEECCCCCCHHHHHHCCCEEEEE
TTAQNAVVDHRMEQLGITHYYKGQVDKRSAYQHLKKTLGLNDEEFAYIGDDLPDLPLIQQ
ECCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHH
VGLGVAVSNAVPQVLEFADWRTERTGGRGAVRELCDLILNAQNKAELAITGYLKQ
HCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]