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The map label for this gene is kdsD [H]

Identifier: 148360514

GI number: 148360514

Start: 1023309

End: 1024271

Strand: Reverse

Name: kdsD [H]

Synonym: LPC_2455

Alternate gene names: 148360514

Gene position: 1024271-1023309 (Counterclockwise)

Preceding gene: 148360505

Following gene: 148360515

Centisome position: 28.64

GC content: 40.81

Gene sequence:

>963_bases
ATGAACTTTTGCACACTTGGACTAGCAGTTATTGAAACTGAAGCACAAGCTGTATTTGAGCTAACTCAACGAATTGATGA
ACATTTTGAAAAAGCTTGTGAATTACTCTTATCATGCAAAGGGCGTATCGTCGTCACAGGCATGGGAAAATCTGGCCATA
TAGCTAATAAACTGGCCTCTACTTTTTCCAGCACTGGCAGCCCCGCTTTTTTTATGCATCCTGGAGAAGCAAGTCATGGA
GACTTGGGTATGATAACTCGCCAGGATATAGTTGTTGCCATTTCCAATTCAGGCAATACCCACGAAATAGTTACTTTGCT
TCCATTATTAAAAAGGCTTGAAGTCCCCTTAATTACATTGACCGGCAATAAACAATCAACTCTGGCTAAATCTGCAGATG
TCAATCTGGATGTCAGTATTAAACAAGAGGCTTGCCCTCTGGGTCTTGCTCCAACAACCAGTACTACGGTATCGCTGGTT
ATGGGGGATGCATTGGCTATATCTCTTTTACAAGCACGGGGATTTAGTGCAGAGGACTTCGCTCTTTCCCATCCTGGAGG
CGCACTTGGCAAAAAATTGTTGCTAAAAATAGACGATTTATGTCATACAGGAGAGCAACTTCCCTTAGCGAATGAAAACG
CAACAGTGAGTGACGCTTTAATTGAAGTCACAAATAAAAAGCTGGGAATGACTTGTGTTGTAGACAACCATGGCTATTTA
GTGGGTGTATATACTGATGGAGATATCCGTCGAACATTGACACGTCAATTTAATATCAACACTACTCTAATCAAGGACGT
CATGACTAAAAACTGCAGAACTATTTCTAAAGGCATGTTGGCTGCCGAAGCTTTAGCAATCATGCAAAAATATAGCATCA
CATCCTTGGTAGTAGTTGAAAATGATAATAGACCTTATGCGGTACTCCATTTACATGACTTGCTAAAAGCGGGTGTTTTT
TAA

Upstream 100 bases:

>100_bases
TATAAGCCATTAGTTGGTATCAGTTACTGAAATATAGGGTACATCATTTAAATACATTATGTTAGAATGAAAACCAAACA
AAATTACGACTCAATGACCT

Downstream 100 bases:

>100_bases
TACAGAGATAGAAATGAACGAACTATTGGAAAAAGCGAAAAAAATTAAATGTCTTATTTGTGATGTAGACGGGGTGCTCA
GTGATGGCTTACTTCACATT

Product: polysialic acid capsule expression protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNFCTLGLAVIETEAQAVFELTQRIDEHFEKACELLLSCKGRIVVTGMGKSGHIANKLASTFSSTGSPAFFMHPGEASHG
DLGMITRQDIVVAISNSGNTHEIVTLLPLLKRLEVPLITLTGNKQSTLAKSADVNLDVSIKQEACPLGLAPTTSTTVSLV
MGDALAISLLQARGFSAEDFALSHPGGALGKKLLLKIDDLCHTGEQLPLANENATVSDALIEVTNKKLGMTCVVDNHGYL
VGVYTDGDIRRTLTRQFNINTTLIKDVMTKNCRTISKGMLAAEALAIMQKYSITSLVVVENDNRPYAVLHLHDLLKAGVF

Sequences:

>Translated_320_residues
MNFCTLGLAVIETEAQAVFELTQRIDEHFEKACELLLSCKGRIVVTGMGKSGHIANKLASTFSSTGSPAFFMHPGEASHG
DLGMITRQDIVVAISNSGNTHEIVTLLPLLKRLEVPLITLTGNKQSTLAKSADVNLDVSIKQEACPLGLAPTTSTTVSLV
MGDALAISLLQARGFSAEDFALSHPGGALGKKLLLKIDDLCHTGEQLPLANENATVSDALIEVTNKKLGMTCVVDNHGYL
VGVYTDGDIRRTLTRQFNINTTLIKDVMTKNCRTISKGMLAAEALAIMQKYSITSLVVVENDNRPYAVLHLHDLLKAGVF
>Mature_320_residues
MNFCTLGLAVIETEAQAVFELTQRIDEHFEKACELLLSCKGRIVVTGMGKSGHIANKLASTFSSTGSPAFFMHPGEASHG
DLGMITRQDIVVAISNSGNTHEIVTLLPLLKRLEVPLITLTGNKQSTLAKSADVNLDVSIKQEACPLGLAPTTSTTVSLV
MGDALAISLLQARGFSAEDFALSHPGGALGKKLLLKIDDLCHTGEQLPLANENATVSDALIEVTNKKLGMTCVVDNHGYL
VGVYTDGDIRRTLTRQFNINTTLIKDVMTKNCRTISKGMLAAEALAIMQKYSITSLVVVENDNRPYAVLHLHDLLKAGVF

Specific function: Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789588, Length=318, Percent_Identity=55.0314465408805, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI87082151, Length=307, Percent_Identity=42.0195439739414, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00571 CBS; PF01380 SIS [H]

EC number: =5.3.1.13 [H]

Molecular weight: Translated: 34346; Mature: 34346

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFCTLGLAVIETEAQAVFELTQRIDEHFEKACELLLSCKGRIVVTGMGKSGHIANKLAS
CCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
TFSSTGSPAFFMHPGEASHGDLGMITRQDIVVAISNSGNTHEIVTLLPLLKRLEVPLITL
HHHCCCCCEEEECCCCCCCCCEEEEEECEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEE
TGNKQSTLAKSADVNLDVSIKQEACPLGLAPTTSTTVSLVMGDALAISLLQARGFSAEDF
ECCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCC
ALSHPGGALGKKLLLKIDDLCHTGEQLPLANENATVSDALIEVTNKKLGMTCVVDNHGYL
EEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCEE
VGVYTDGDIRRTLTRQFNINTTLIKDVMTKNCRTISKGMLAAEALAIMQKYSITSLVVVE
EEEEECCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
NDNRPYAVLHLHDLLKAGVF
CCCCCEEEEEHHHHHHHCCC
>Mature Secondary Structure
MNFCTLGLAVIETEAQAVFELTQRIDEHFEKACELLLSCKGRIVVTGMGKSGHIANKLAS
CCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
TFSSTGSPAFFMHPGEASHGDLGMITRQDIVVAISNSGNTHEIVTLLPLLKRLEVPLITL
HHHCCCCCEEEECCCCCCCCCEEEEEECEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEE
TGNKQSTLAKSADVNLDVSIKQEACPLGLAPTTSTTVSLVMGDALAISLLQARGFSAEDF
ECCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCC
ALSHPGGALGKKLLLKIDDLCHTGEQLPLANENATVSDALIEVTNKKLGMTCVVDNHGYL
EEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCEE
VGVYTDGDIRRTLTRQFNINTTLIKDVMTKNCRTISKGMLAAEALAIMQKYSITSLVVVE
EEEEECCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
NDNRPYAVLHLHDLLKAGVF
CCCCCEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]