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The map label for this gene is atpA1 [H]

Identifier: 148360288

GI number: 148360288

Start: 1263319

End: 1264791

Strand: Reverse

Name: atpA1 [H]

Synonym: LPC_2225

Alternate gene names: 148360288

Gene position: 1264791-1263319 (Counterclockwise)

Preceding gene: 148360287

Following gene: 148360289

Centisome position: 35.36

GC content: 43.11

Gene sequence:

>1473_bases
ATGAATTGGTCTAACACCCCTTCTTTTCTTGAGAAGCAACGACAGCGCCTTAAGCGCTATCAATTTCAAATCAAGGTATC
CGAACAAGGACGGGTGGTTTCTGTTGGAGATGGTATCATCTGGATTAAGGGCTTACCAGGGGCTGCCATCGATGAAATTC
TTATTTCAGAGGATGAGTGCTGTATCGCGATGGTGTTCCACCTCACCGAAGAGCTGGTTGGCGCTGTGATGCTGGTACAA
ACCAAAAAATTAAAAGCAGGCACCCCTATTTTCCCTCTGAAACGCGTATTGAGTATTCCTGTAGGCGATAAACTGCTTGG
GCGAGTGATTGATCCTCTAGGCCATCCATTAGACGGCGGTGAGATTCCGCCCCATGAAGAACAAGGATTACTGGATAGGC
TGTCCCCCCATATTCTTCACCGTGACTTTGTGAATCGACCATTGTACACAGGAAATAAGATGCTTGATAATCTAATTCCC
ATTGGAAAAGGACAAAGGGAGTTACTGATTGGGGATAATGGGCTTGGTAAAAGTGCTTTGGCCCTTGACATTGTGATGAA
TCAAAAAGATAAAAAAGTGTATTGTGTCTATGTGTTGATTGGCCAAAAACGTTCCACGGTAAGCTCTACCATTCAATTAT
TAAAAAAAGCCAACGCCTTGGACTATACAACTGTTGTGGTGGCCCAAGCGACGGCCTTACCAGGATTACTTTATCTAGCA
CCTTTTGCAGGGTGCGCCATTGCCGAACACTGGATGAAAAAGGGCTTAGATACCCTGGTGGTCTATGATGATTTGAGTGC
TCATGCCAATAGTTATCGTGAACTGTCCCTTTTACTGCGTAGACCTCCTGGACGTGAAGCATTTCCTGCAGACATTTTTT
ATCTGCATTCCCGTTTATTAGAACGCTCCACCTGTCTTTCCCCTGCTATGGGCGGCGGCAGTATGACGGCGTTGCCTATT
ATTGAAACCAAAGAAGGTGAAATGGCCACTTATATTCCAACGAATCTCATCTCCATCACCGATGGGCAAATATTTTTTGA
TGAATCGTTATTCTCTTCTGGATTTCTTCCCGCCATTGATATCACCAAATCGGTCTCACGAGTCGGTGCTAAAGCGCAGC
ATCCGCAAATTAAAAAAGAATCCGGTCGAATGAAACTTGATTACCTGCAATTTCTTGATTTGGAACTGTTCACCCGCTTT
GGAGCAAAACTGGATGCCAAAATGCAAAAACAGATTCAAAAAGGGCGAGTTTTAAGAGAAATTCTAAAACAAGAACGATT
TTCACCACTACCCATTGAATTTCAACTCGCATGGCTTATTGCTTACAATGAGGGTTTCTTTGACGAATCGAATTTAGAAG
ACATCCCTCAAATTCTCAAAAAAATAGAGAAAGAAATAAAACAGAGCAATTTATCCTTGGGAAGTCCACGAGAACAATGG
AAAAAAGCGATAAAAGAATGGCTAATGGCATAG

Upstream 100 bases:

>100_bases
GAAAATCCAAAGCTTCTCGCGGGATTAACCCTTCAAATGGGCCCCATGTGCTTGCAAGCCAATCTTCGTGATGAATTAAA
ATTCTTTACAGAGACAAAAA

Downstream 100 bases:

>100_bases
AACGGACTTCTTATCCATTCCAAAATAATGGGTCTCATTGACCGCAGGGATGTATTATGACAAAGCGAACGAAATTAAAA
GAACATCTTCATACTTTAGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNWSNTPSFLEKQRQRLKRYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQ
TKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPHILHRDFVNRPLYTGNKMLDNLIP
IGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKKANALDYTTVVVAQATALPGLLYLA
PFAGCAIAEHWMKKGLDTLVVYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPAMGGGSMTALPI
IETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGAKAQHPQIKKESGRMKLDYLQFLDLELFTRF
GAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDESNLEDIPQILKKIEKEIKQSNLSLGSPREQW
KKAIKEWLMA

Sequences:

>Translated_490_residues
MNWSNTPSFLEKQRQRLKRYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQ
TKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPHILHRDFVNRPLYTGNKMLDNLIP
IGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKKANALDYTTVVVAQATALPGLLYLA
PFAGCAIAEHWMKKGLDTLVVYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPAMGGGSMTALPI
IETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGAKAQHPQIKKESGRMKLDYLQFLDLELFTRF
GAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDESNLEDIPQILKKIEKEIKQSNLSLGSPREQW
KKAIKEWLMA
>Mature_490_residues
MNWSNTPSFLEKQRQRLKRYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQ
TKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPHILHRDFVNRPLYTGNKMLDNLIP
IGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKKANALDYTTVVVAQATALPGLLYLA
PFAGCAIAEHWMKKGLDTLVVYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPAMGGGSMTALPI
IETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGAKAQHPQIKKESGRMKLDYLQFLDLELFTRF
GAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDESNLEDIPQILKKIEKEIKQSNLSLGSPREQW
KKAIKEWLMA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=471, Percent_Identity=43.5244161358811, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI4757810, Length=471, Percent_Identity=43.5244161358811, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI32189394, Length=390, Percent_Identity=23.8461538461538, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI19913426, Length=302, Percent_Identity=24.5033112582781, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI19913428, Length=288, Percent_Identity=23.9583333333333, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790172, Length=462, Percent_Identity=42.2077922077922, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788251, Length=270, Percent_Identity=31.1111111111111, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790170, Length=310, Percent_Identity=24.5161290322581, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=459, Percent_Identity=43.5729847494553, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71988080, Length=459, Percent_Identity=43.5729847494553, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71988074, Length=459, Percent_Identity=40.958605664488, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25144756, Length=393, Percent_Identity=21.6284987277354, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17510931, Length=290, Percent_Identity=25.5172413793103, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=449, Percent_Identity=44.097995545657, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6319603, Length=293, Percent_Identity=25.2559726962457, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=332, Percent_Identity=23.1927710843373, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24658560, Length=454, Percent_Identity=45.1541850220264, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24638766, Length=310, Percent_Identity=23.8709677419355, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28574560, Length=311, Percent_Identity=24.4372990353698, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54906; Mature: 54906

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWSNTPSFLEKQRQRLKRYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDEC
CCCCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHCCCCCH
CIAMVFHLTEELVGAVMLVQTKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
EIPPHEEQGLLDRLSPHILHRDFVNRPLYTGNKMLDNLIPIGKGQRELLIGDNGLGKSAL
CCCCCCCCCHHHHHCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCHHE
ALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKKANALDYTTVVVAQATALPGLLYLA
EEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
PFAGCAIAEHWMKKGLDTLVVYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLL
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ERSTCLSPAMGGGSMTALPIIETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAID
HHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEECHHHHCCCCCCHHH
ITKSVSRVGAKAQHPQIKKESGRMKLDYLQFLDLELFTRFGAKLDAKMQKQIQKGRVLRE
HHHHHHHHCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ILKQERFSPLPIEFQLAWLIAYNEGFFDESNLEDIPQILKKIEKEIKQSNLSLGSPREQW
HHHHHCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KKAIKEWLMA
HHHHHHHHCC
>Mature Secondary Structure
MNWSNTPSFLEKQRQRLKRYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDEC
CCCCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHCCCCCH
CIAMVFHLTEELVGAVMLVQTKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
EIPPHEEQGLLDRLSPHILHRDFVNRPLYTGNKMLDNLIPIGKGQRELLIGDNGLGKSAL
CCCCCCCCCHHHHHCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCHHE
ALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKKANALDYTTVVVAQATALPGLLYLA
EEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
PFAGCAIAEHWMKKGLDTLVVYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLL
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ERSTCLSPAMGGGSMTALPIIETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAID
HHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEECHHHHCCCCCCHHH
ITKSVSRVGAKAQHPQIKKESGRMKLDYLQFLDLELFTRFGAKLDAKMQKQIQKGRVLRE
HHHHHHHHCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ILKQERFSPLPIEFQLAWLIAYNEGFFDESNLEDIPQILKKIEKEIKQSNLSLGSPREQW
HHHHHCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KKAIKEWLMA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA