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The map label for this gene is fabG [H]

Identifier: 148359774

GI number: 148359774

Start: 2639681

End: 2640433

Strand: Direct

Name: fabG [H]

Synonym: LPC_1699

Alternate gene names: 148359774

Gene position: 2639681-2640433 (Clockwise)

Preceding gene: 148359773

Following gene: 148359775

Centisome position: 73.81

GC content: 41.04

Gene sequence:

>753_bases
ATGAATATCCTGATTACTGGCGGCTCCTCTGATATTGCCCAAGCCATAGCGAAACGACGCAGTGAATTAGGCGATAAGAT
CATCATTACCTGTTCTAACGATACCAGTCTTAATGAAACACTTGCAATATACCGCCAACAAAACATTGACGTGACGGGTT
TCATTTATAATTTTGCAGATCCTCAAGCTTGTGAAAACGATTTGGAACTGATTTTAAGAGAACCACTTGATGGCATCATA
TTAAATGCGTTCACTCGGGTCACCCAACTGCGTAAATTACATGCATTGCCCTATCACGCTGTTCGTACTTACCTGGATAA
CAATCTCAATGGCAACATTTGGCTTATTCATCGTTTATTACCTGCCTTGCTAAAAAATAAATTCGGGCGACTCGTGCTCA
TTTCAAGTCTTTCGGCGATAGCTGGAACCAGCCGATACCCTGTTTATTGTGCGGCAAAAGCGGCTCTGGAAGGATTATTT
TTAAATTTGGCTGTTGATTATAGTGCTAACAATATCTTGTCTAATATAGTACGCGTAGGCTTAATTAAAACCTCCAGAAC
AGAGCAATTTTGGAAAAATCCAGCCTATCAAGAAAAAGTAATGCGAATTATTCCACAGGGCACTATGGGTGAACCAACTC
AAGTTGCGGAAGCCATTGATCCACTTTTGTCAAAAACCTCGTTTATGACGGGATCAGTTGTAACAGTCAGTGGTGGTCTG
CCTTTAATGCGTTCAGAAGGATTGTTGTCATGA

Upstream 100 bases:

>100_bases
AACGTGAATTTGAAATTAAAATCCCTGTCATTCCACTGGAGAAAGAGCATTACGAATCGATCAATACTATTGAACAATAC
CTCATTGAGCTGGGGGCAAA

Downstream 100 bases:

>100_bases
ATTTTTTCCGTTGTGAAAAACCCATCTATATAAAAGGCCCTTTTGTTGCGCTTCCCGAGAGAGTCATGAGCAACCAAGAT
GTTCTCAATTGGATGAACAG

Product: 3-oxoacyl reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNILITGGSSDIAQAIAKRRSELGDKIIITCSNDTSLNETLAIYRQQNIDVTGFIYNFADPQACENDLELILREPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSAIAGTSRYPVYCAAKAALEGLF
LNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVMRIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS

Sequences:

>Translated_250_residues
MNILITGGSSDIAQAIAKRRSELGDKIIITCSNDTSLNETLAIYRQQNIDVTGFIYNFADPQACENDLELILREPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSAIAGTSRYPVYCAAKAALEGLF
LNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVMRIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS
>Mature_250_residues
MNILITGGSSDIAQAIAKRRSELGDKIIITCSNDTSLNETLAIYRQQNIDVTGFIYNFADPQACENDLELILREPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSAIAGTSRYPVYCAAKAALEGLF
LNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVMRIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=24.896265560166, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=23.6734693877551, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=28.6885245901639, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082100, Length=156, Percent_Identity=30.1282051282051, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=24.4897959183673, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=24.3801652892562, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=26.4462809917355, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27536; Mature: 27536

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILITGGSSDIAQAIAKRRSELGDKIIITCSNDTSLNETLAIYRQQNIDVTGFIYNFAD
CEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCC
PQACENDLELILREPLDGIILNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEHHHHH
PALLKNKFGRLVLISSLSAIAGTSRYPVYCAAKAALEGLFLNLAVDYSANNILSNIVRVG
HHHHHHCCCCEEEEEHHHHHHCCCCCCEEEEHHHHHHHEEEEEEEECCHHHHHHHHHHHH
LIKTSRTEQFWKNPAYQEKVMRIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
PLMRSEGLLS
CCCCCCCCCC
>Mature Secondary Structure
MNILITGGSSDIAQAIAKRRSELGDKIIITCSNDTSLNETLAIYRQQNIDVTGFIYNFAD
CEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCC
PQACENDLELILREPLDGIILNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEHHHHH
PALLKNKFGRLVLISSLSAIAGTSRYPVYCAAKAALEGLFLNLAVDYSANNILSNIVRVG
HHHHHHCCCCEEEEEHHHHHHCCCCCCEEEEHHHHHHHEEEEEEEECCHHHHHHHHHHHH
LIKTSRTEQFWKNPAYQEKVMRIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
PLMRSEGLLS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA