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The map label for this gene is kdsB [H]

Identifier: 148359466

GI number: 148359466

Start: 2232812

End: 2233564

Strand: Reverse

Name: kdsB [H]

Synonym: LPC_1373

Alternate gene names: 148359466

Gene position: 2233564-2232812 (Counterclockwise)

Preceding gene: 148359467

Following gene: 148359465

Centisome position: 62.45

GC content: 40.64

Gene sequence:

>753_bases
ATGAGCCATAATTTTCATGTGATTATACCAGCCAGATATCACTCCAGTCGTTTTCCAGGTAAATTACTTCAAGAAATTAA
CGGCATTACTGTGATTGAACGAGTTTACAGGCAAGCACTTCTGGCAGAACCAAAGTCGGTGATTATTGCCACTGATCATG
ATGAGATAGCTGACCGTGCAATCCAATTTGGAGCGGAGGTTGTAATCACTTCACATACGCACCAAACTGGAACTGATCGA
ATTGCAGAGGTTGTCGCCAAGGGTAGCTTTGCTCCTGATGACGTCATTGTCAATGTGCAAGGTGATGAGCCATTTATCCG
ACCCAAATTAATTCAACAAGTTGCTTGCTCTTTAACGAAGACAAAGGCGCCTGTGTCTACTTTATGCTGGCCTATTAGTA
GCCTTGAAATATTAAATAACCCTAATGTGGTTAAAGTGGTGTGCACTCGAGATAATCACGCTCTTTATTTTTCAAGAAGC
GCAATTCCTTATCACAGAGATAATAAAAGCGCTTATTCCAATACCTTCAGGCATATCGGTTTATATGCTTATCGTGCTGC
CTTTTTACTGGAATTCGTTAGCTGGCCACCCTGTACCTTGGAACAAATAGAGTGTTTGGAGCAATTGCGCATCCTATGGT
CAGGTTTCTCAATCCGGGTTGATGAGGCCTGTGAAGAACCTTTACAGGATATTAATACAAAAGAAGATTTGATTTTGGCT
CAGCAATATTTTCTTGATATTTCCAATATATAA

Upstream 100 bases:

>100_bases
TCTGCAAATTTGATAGGCTGGCATTTCCTGTTCGTGATGATATTCCTGTTATGCTGGAACAAGAAGCGCGTTTGATTCCT
CTGGAAGAGAAAGATAAATT

Downstream 100 bases:

>100_bases
CTCATTGTAATTTATCGTTTTTTCTATGAGGGAATGTTTTATCCGCTCCGTATGGTCGCCACTCAATTTTCATCATAATG
GAGTGACGATCTTGACTTTT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRS
AIPYHRDNKSAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
QQYFLDISNI

Sequences:

>Translated_250_residues
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRS
AIPYHRDNKSAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
QQYFLDISNI
>Mature_249_residues
SHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDRI
AEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRSA
IPYHRDNKSAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILAQ
QYFLDISNI

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=239, Percent_Identity=47.2803347280335, Blast_Score=214, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28292; Mature: 28160

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRA
CCCCEEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
IQFGAEVVITSHTHQTGTDRIAEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTK
HHCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
TKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRSAIPYHRDNKSAYSNTFRHIG
CCCCHHHHHHCCCHHHCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
LYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHH
QQYFLDISNI
HHHHHHHCCC
>Mature Secondary Structure 
SHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRA
CCCEEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
IQFGAEVVITSHTHQTGTDRIAEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTK
HHCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
TKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRSAIPYHRDNKSAYSNTFRHIG
CCCCHHHHHHCCCHHHCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
LYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHH
QQYFLDISNI
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA