Click here to switch to the map view.

The map label for this gene is ydiC [H]

Identifier: 148359288

GI number: 148359288

Start: 2026403

End: 2026771

Strand: Reverse

Name: ydiC [H]

Synonym: LPC_1184

Alternate gene names: 148359288

Gene position: 2026771-2026403 (Counterclockwise)

Preceding gene: 148359289

Following gene: 148359287

Centisome position: 56.67

GC content: 36.04

Gene sequence:

>369_bases
ATGAGTGTAGAAATACAACAAGCGAGCAGTACGAACCCCAACATCACTTTCAGTGAATCGGCAATAAAGCACCTGGTCAC
CTATCTGGAGAAAAACCCAGGAAACAAGGGAGTAAGATTGTCTGTAAAAAAGACGGGATGCTCGGGATTATCTTATGTAG
TGGATTATGTAAAAGAACCTTCAGAAGGAGATATGATAGCTTCTTTATCTAAAGATTATCTGGTATGCGTTGATAAAACA
AGTTATCCATTTCTTAAAAATATGCAAGTTGATTATGTGAAACAAGGTTTAAATTATAAATTTATTTTTAATAATCCCAA
TCAGACGGGGCAATGTGGTTGTGGAGAGAGCTTTACTGTAAGTCAGTAA

Upstream 100 bases:

>100_bases
TTACAAATAACAAATAATCAGTATCCTGTAGCAGTCCAGGTAGAGGATATATATAAAGAAGCATTGACTTTGATGCGTAA
GAAATTTGAGAGGTAAAGCA

Downstream 100 bases:

>100_bases
AATAAGCAGAAAATCTACGATGCTTCTTTAATATTATCAATAAGCGGCCGGCTTGAAGGGCAGTCGCAATATCCAGCCTC
ATGGTTTTATATTCTTTTTA

Product: HesB family transporter protein

Products: NA

Alternate protein names: Iron-sulfur cluster assembly protein [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MSVEIQQASSTNPNITFSESAIKHLVTYLEKNPGNKGVRLSVKKTGCSGLSYVVDYVKEPSEGDMIASLSKDYLVCVDKT
SYPFLKNMQVDYVKQGLNYKFIFNNPNQTGQCGCGESFTVSQ

Sequences:

>Translated_122_residues
MSVEIQQASSTNPNITFSESAIKHLVTYLEKNPGNKGVRLSVKKTGCSGLSYVVDYVKEPSEGDMIASLSKDYLVCVDKT
SYPFLKNMQVDYVKQGLNYKFIFNNPNQTGQCGCGESFTVSQ
>Mature_121_residues
SVEIQQASSTNPNITFSESAIKHLVTYLEKNPGNKGVRLSVKKTGCSGLSYVVDYVKEPSEGDMIASLSKDYLVCVDKTS
YPFLKNMQVDYVKQGLNYKFIFNNPNQTGQCGCGESFTVSQ

Specific function: Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that iscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transi

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=120, Percent_Identity=35, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788877, Length=107, Percent_Identity=44.8598130841121, Blast_Score=96, Evalue=6e-22,
Organism=Escherichia coli, GI1787974, Length=107, Percent_Identity=42.0560747663551, Blast_Score=95, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25146411, Length=111, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=120, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=39.622641509434, Blast_Score=82, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24642263, Length=111, Percent_Identity=35.1351351351351, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR011302 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13479; Mature: 13348

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEIQQASSTNPNITFSESAIKHLVTYLEKNPGNKGVRLSVKKTGCSGLSYVVDYVKEP
CCEECCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCC
SEGDMIASLSKDYLVCVDKTSYPFLKNMQVDYVKQGLNYKFIFNNPNQTGQCGCGESFTV
CCCCEEEECCCCEEEEECCCCCCHHHCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
SQ
CC
>Mature Secondary Structure 
SVEIQQASSTNPNITFSESAIKHLVTYLEKNPGNKGVRLSVKKTGCSGLSYVVDYVKEP
CEECCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCC
SEGDMIASLSKDYLVCVDKTSYPFLKNMQVDYVKQGLNYKFIFNNPNQTGQCGCGESFTV
CCCCEEEECCCCEEEEECCCCCCHHHCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
SQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA