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The map label for this gene is iolE [H]

Identifier: 148359185

GI number: 148359185

Start: 1891569

End: 1892453

Strand: Reverse

Name: iolE [H]

Synonym: LPC_1079

Alternate gene names: 148359185

Gene position: 1892453-1891569 (Counterclockwise)

Preceding gene: 148359186

Following gene: 148359184

Centisome position: 52.91

GC content: 38.98

Gene sequence:

>885_bases
ATGAGTATTCAACTTGGTATCGCGCCAATTAATTGGTGCAATGATGATGATCCGAATTTAGGTAAAGACATTAGTTTTGA
GCAATGTATTAACGAAATGGCTTTGGCAGGTTATTCTGGCACTGAGCTGGGGAATAAATACCCACGAGATGCAACAACAT
TAAAAGCTGCTTTGGAACAACGAGGTTTACAATTATCCAGTTCATGGTTTAGCACTTATTTTACTGAGGCCAATGCTTTT
GAAAAAACCGTATCAAGATTTCTTGAGCACTTAAGTTTTATGCGTGCATTAGGTGCGTCGTATATTAATGTTTGTGAATG
TGGTCATGCTATTCAAGGCACTGATTTACCGATATTAAGTGCTCATATCCCTCAATTTACTCAAGAGCAATGGAGTTTAT
TGATTCAAGGGCTGCATACCTTAGGCCGAATTGCTTACGACTTCAATATGAAGATCGTTTATCATTACCATGCAGGGACT
GGGGTGTTTTGGGAGAAAGACATTGATTTTTTAATGACCAATACCAGTCCAAAGTTGCTTTCTCTATTACTTGACACAGG
ACATGCTGTCTTTTCAGGAATAGATCCGGTTAATTTAATAAATAAGTACGGTGATCGTATTTTGTATGTTCATCTGAAAG
ACATTCGCCCTGAGGTCTTGAGACGAGTTGAAATGGAGAGACTCAGCTTTATGGATGCAGTAAGAAGAGGGGTATTTACT
GTGCCTGGTGATGGAGCAATTGATTTCATACCTATATGGGCAGGGCTGCAAAAACATCGCTATAATGGATGGATGATAGT
GGAGGCGGAGCAGGATCCGGAAAAAGCACATCCTTTGGAATACGCCAAAAAAGCATATGATTATTTGCATTCATTTATTC
ATTAA

Upstream 100 bases:

>100_bases
GAGTTGCTGAGGTATCTCAATCAGAATCAGTGAGTAAAGCTTACCAAATGATGCAAGAGCAAATTGAAACAGTTAGACAA
TATTGAAGATGGAAGTGAAG

Downstream 100 bases:

>100_bases
AGAAAGGCTGATGATTGAAGATTTAATAAAGTTTACTTTATTAAAAATACCAGGGAAGCTTAAGAGTTATCTGTTTATAG
GCTGAAATCTGGTTAAGTTC

Product: myo-inositol catabolism protein IolE

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSIQLGIAPINWCNDDDPNLGKDISFEQCINEMALAGYSGTELGNKYPRDATTLKAALEQRGLQLSSSWFSTYFTEANAF
EKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGT
GVFWEKDIDFLMTNTSPKLLSLLLDTGHAVFSGIDPVNLINKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRRGVFT
VPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH

Sequences:

>Translated_294_residues
MSIQLGIAPINWCNDDDPNLGKDISFEQCINEMALAGYSGTELGNKYPRDATTLKAALEQRGLQLSSSWFSTYFTEANAF
EKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGT
GVFWEKDIDFLMTNTSPKLLSLLLDTGHAVFSGIDPVNLINKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRRGVFT
VPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH
>Mature_293_residues
SIQLGIAPINWCNDDDPNLGKDISFEQCINEMALAGYSGTELGNKYPRDATTLKAALEQRGLQLSSSWFSTYFTEANAFE
KTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGTG
VFWEKDIDFLMTNTSPKLLSLLLDTGHAVFSGIDPVNLINKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRRGVFTV
PGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 33424; Mature: 33292

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQLGIAPINWCNDDDPNLGKDISFEQCINEMALAGYSGTELGNKYPRDATTLKAALEQ
CEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
RGLQLSSSWFSTYFTEANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
AHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGTGVFWEKDIDFLMTNTSPKLL
HHCCHHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEECCCCCEEECCCCEEEECCCHHHH
SLLLDTGHAVFSGIDPVNLINKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRRGVFT
HHHHHCCHHHHCCCCHHHHHHHCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHCCEEE
VPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH
CCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIQLGIAPINWCNDDDPNLGKDISFEQCINEMALAGYSGTELGNKYPRDATTLKAALEQ
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
RGLQLSSSWFSTYFTEANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
AHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGTGVFWEKDIDFLMTNTSPKLL
HHCCHHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEECCCCCEEECCCCEEEECCCHHHH
SLLLDTGHAVFSGIDPVNLINKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRRGVFT
HHHHHCCHHHHCCCCHHHHHHHCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHCCEEE
VPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH
CCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA