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The map label for this gene is fabH [H]

Identifier: 148359166

GI number: 148359166

Start: 1869012

End: 1869971

Strand: Reverse

Name: fabH [H]

Synonym: LPC_1060

Alternate gene names: 148359166

Gene position: 1869971-1869012 (Counterclockwise)

Preceding gene: 148359169

Following gene: 148359165

Centisome position: 52.29

GC content: 42.5

Gene sequence:

>960_bases
ATGGGAAAATATTTACCCGCAAACATAGTGTTTTCATCTGATCTGGATAAAAAACTCAATCTTCCTAAAGGCAGTGTTCA
GAAGAAGTCCGGATTAGTTTCCAGGCATTTTGCCAGAGTCAGTGAAACAACCTCCTATATGGCAAGTCAAGCTGCATTAC
ACGCTGTGGAACAAGCAGGAATTACTTTAGCTGAAATTGATGCCATTATTGGGGCTTGTGGAGCCGGAGAGCAACCTATA
CCATGTACGGCGGTTCTGGTTCAAAAACAATTGGGATTAGATAATTCAGGAATCGCCTGTTTTGATATTAACAGTACCTG
TCTTAGTTTTCTCACTGCACTCGATGCGGCATCATATATGCTCTCAGGGGGCAGATTTAATCGTATACTTATTGTATCAA
GTGATATCCCTTCATTTGGCCTGGATTGGAGCGACTTGGAAACCTGTACGATTTTTGGTGACGGGGCAGCTGCTTGTGTT
GTTGAAAGAAGCAATGATTCCAGTCGGATTCTTTCTGCTCATATGAAAACATACAGTTTGGGTGCTGCCTTTTGCGAGGT
CCAGGCTGGAGGAACATTCATGCCGCCTGCGAGTAAGTACGATAAGAAATACGGTTTATTTAAAATGGATGGAAAGCGTG
TATTCAAACTGGCCAGCCAAATGATTGGGCCCATGCAAGAGGAGTTATTTGCTAAAGCTAGTATAACTCTAAATGATGTT
GATTGGGTTGTCCCACATCAAGCCAGCTTGCTTGCTATGCATCATATACGTAAAAAGCTTGGCATCCCTGGTGAAAAATT
TGTTGATATTTACACGACGCATGGCAATCAAATGGCTGCTTCTCTGCCTTCTGCATTGTGTCATTTGATCCATAATCATA
ATTTAGAGCGTGGGCAGTTGGTTTATTTATTAGGTACTGGCGCTGGATTGTCAGCTGCTGGAATGATACTGGAGTATTAG

Upstream 100 bases:

>100_bases
CCTTTAAAAAAGTTCTCTTTGACTATAATAAGCCTTATAGTACAATAATTGCTCCATCCTTTAACAAGTCAGTTCTATGT
CGTCAGCAAAAATCATCGGA

Downstream 100 bases:

>100_bases
TATGGTTTCAGTTGTAACCGGCGCTACAGGATGTTTAGGTTTAAATCTTACAAGACGCTTGATTAAGGAAGGCCATGCTG
TCATTGCATTAGGACGCAAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MGKYLPANIVFSSDLDKKLNLPKGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAGITLAEIDAIIGACGAGEQPI
PCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACV
VERSNDSSRILSAHMKTYSLGAAFCEVQAGGTFMPPASKYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAKASITLNDV
DWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQLVYLLGTGAGLSAAGMILEY

Sequences:

>Translated_319_residues
MGKYLPANIVFSSDLDKKLNLPKGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAGITLAEIDAIIGACGAGEQPI
PCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACV
VERSNDSSRILSAHMKTYSLGAAFCEVQAGGTFMPPASKYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAKASITLNDV
DWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQLVYLLGTGAGLSAAGMILEY
>Mature_318_residues
GKYLPANIVFSSDLDKKLNLPKGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAGITLAEIDAIIGACGAGEQPIP
CTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACVV
ERSNDSSRILSAHMKTYSLGAAFCEVQAGGTFMPPASKYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAKASITLNDVD
WVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQLVYLLGTGAGLSAAGMILEY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=324, Percent_Identity=30.5555555555556, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34198; Mature: 34067

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYLPANIVFSSDLDKKLNLPKGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAG
CCCCCCCEEEECCCCCHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ITLAEIDAIIGACGAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYM
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
LSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACVVERSNDSSRILSAHMKTYSL
HCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
GAAFCEVQAGGTFMPPASKYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAKASITLNDV
CCEEEEEECCCCCCCCCHHHHCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHEEEECCC
DWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQL
CEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCE
VYLLGTGAGLSAAGMILEY
EEEEECCCCCHHCCCEECC
>Mature Secondary Structure 
GKYLPANIVFSSDLDKKLNLPKGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAG
CCCCCCEEEECCCCCHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ITLAEIDAIIGACGAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYM
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
LSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACVVERSNDSSRILSAHMKTYSL
HCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
GAAFCEVQAGGTFMPPASKYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAKASITLNDV
CCEEEEEECCCCCCCCCHHHHCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHEEEECCC
DWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQL
CEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCE
VYLLGTGAGLSAAGMILEY
EEEEECCCCCHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]