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The map label for this gene is ftsI4 [H]

Identifier: 148359154

GI number: 148359154

Start: 1854722

End: 1856632

Strand: Reverse

Name: ftsI4 [H]

Synonym: LPC_1046

Alternate gene names: 148359154

Gene position: 1856632-1854722 (Counterclockwise)

Preceding gene: 148359155

Following gene: 148359153

Centisome position: 51.91

GC content: 38.04

Gene sequence:

>1911_bases
ATGTTATTAATAGAAATCGTATTGACTATTCATTGCCTGCTTCTTCTCAGTTCACTATTTATAGGGCGCGCCTGGCTAGC
AAATAAACCATCTTTTAAATTGAAATTACTCCGTTTTTTATTGGCCAGTTGCATTATTTCACCAATAATAGTTCATTGTT
TTAATTTTGATCAAAAGCCTGAACGACAAAACTATGTAGCATTTGATGCTTTGCAACAGTATGCAAGGCAACCCATATTT
AAGACAGAATCCTCAAAATTTAATCATGGATCGTCTTCTGCCTTTACATCAATGAATGTGAACTACTGTCAACTCTTAAG
TGTGATGTTTTTTTTAATCGTCTTGTTTCGTAGTTATCACTTGTTATCAGGTTTAGGTCGCTTAAAATTGATGTTGGCTG
AAGCAATCCCATATCGAACCTCCGGAAAACTAGTTATTAAGATTTCTCACCACTGCCATGTTCCTTTCTCAATATTGCTA
TTTAATAAAGCCTACATCGTATTGCCAGTATCCATATTTTCTTCTTCCATGAATGTGAGGATTGCTATTGCTCATGAAGG
GCAACACCATCGTAATGGAGATTGTTCATGGGCCTATTTTATCGAAATCATACGTATTATCTTCTTTGGAAACCCGGGTG
TAACTCAATGGTTTCGTGTTTTAGCAGATTTACAGGAATTGTCATGTGATGAAGTATTGGTTGGACATCAAAAAATTTCG
GCACATGACTATGGTCACTGTCTATTGCAAGTGGTAGAGGCAGTATCCCAATGCTCTCTGGCATCTAACCGGGAAATTAC
ATGCACGGTGGGTATGGCTTTGAACAAAGAAAATGAAGACTGCAAATTTATAATAAGGAGAATTTCAATGCTAACTGCTT
ATTCACCCAATGCATCCAGGCCTTTGCTATTAGGGATAGTCTTTGCAGGATTTTCTATCCTGTCACCAATCTGTGTTGCC
TATTCAGCAGCAGGATCTTTGACGAGTTCCATGGTAAAAGAAGTTGATATTTCTCATTTAGATCCCAGAATGCAGCAGAT
TGCAGAGAGACAAATTACGACAGCCGTCAAACAATATCATGCAAAATCTGGAGTTATTGCAATAGCTGATCCCCAAACAG
GCAATATCATTGCATTTGCTGAATCAAGCAAAAATAAGGGGTTAGAGAGTTGGAAATCACGTATTTTTTCACCCGGATCT
ACTATAAAACCTTTTATTGCAGCAGCTGCAATCAACTCTGGAAATAGCTATGAAACAAAAAATTATGATTGTCATTCACC
TTATTACATAGCAGGCAAAACATTTACAAATTATAGTTCCAATGTTGAATCAGCTTCCTTAGCAGAAGCTATCGCAAAAT
CTATCAATGTATGCCTTATCAGAGTTTCTCAAGAGGCTGGAGTGCCGGTAATCCGTAAAAAGCTCACTGAATTTGGTTTT
GACACAAGCACTTGGTGGCAAGCGGATCGAAGTGATGGTTTACAACTGGCAATGGCTGCACTTGGGGAGAATATCCCTGT
CACAATCGAATCGCTAATAAAATCTTATGCCATTCTTGCTAACAAAGGACACTCATTTGACAGAGGAAATAGTGCCATTA
TTTCAGAAACAACGAATTACTCAATAAATCATATGCTTGAAAATGCTGTTACAAATGGCACTGGAAAACTCGCAGTTATT
CCTGGTGTTTCTGTAGCTGGTAAGACAGGAACTGTAATTGAAAATAATGATAAATATCTTGCTTTGTTTGCCGGGTATGT
GCCAGCTGATAATCCGCGTTATGTTGTATTAGTCGTGATTGAAGAGGGTCATTTCAGTAAAAATGGAAAGACATTAGTTT
CGGGAGGAGAATTGGCCGCACCGGTATTCCGAAATGTCGCAATGGATGCTCTGATCAGTGTAAATCAATAA

Upstream 100 bases:

>100_bases
GACTTTTGTTAGCCAGAAAGTTACAGCATGATGACATTCAAGCCATTGAAGAAGCACTTAAACAATTAAACGCCGGTGAA
AAACAGCCAGAGGTGATGTA

Downstream 100 bases:

>100_bases
CTAGCTTATGGGTTTGCATATCCATATATTCAAGAATGTTGAGGTTGTTATGAAGAAAATAATTATATTTTTGTGCACAG
GATTATTATTTTGCGTCTCT

Product: cell division protein FtsI/penicillin binding protein 2

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MLLIEIVLTIHCLLLLSSLFIGRAWLANKPSFKLKLLRFLLASCIISPIIVHCFNFDQKPERQNYVAFDALQQYARQPIF
KTESSKFNHGSSSAFTSMNVNYCQLLSVMFFLIVLFRSYHLLSGLGRLKLMLAEAIPYRTSGKLVIKISHHCHVPFSILL
FNKAYIVLPVSIFSSSMNVRIAIAHEGQHHRNGDCSWAYFIEIIRIIFFGNPGVTQWFRVLADLQELSCDEVLVGHQKIS
AHDYGHCLLQVVEAVSQCSLASNREITCTVGMALNKENEDCKFIIRRISMLTAYSPNASRPLLLGIVFAGFSILSPICVA
YSAAGSLTSSMVKEVDISHLDPRMQQIAERQITTAVKQYHAKSGVIAIADPQTGNIIAFAESSKNKGLESWKSRIFSPGS
TIKPFIAAAAINSGNSYETKNYDCHSPYYIAGKTFTNYSSNVESASLAEAIAKSINVCLIRVSQEAGVPVIRKKLTEFGF
DTSTWWQADRSDGLQLAMAALGENIPVTIESLIKSYAILANKGHSFDRGNSAIISETTNYSINHMLENAVTNGTGKLAVI
PGVSVAGKTGTVIENNDKYLALFAGYVPADNPRYVVLVVIEEGHFSKNGKTLVSGGELAAPVFRNVAMDALISVNQ

Sequences:

>Translated_636_residues
MLLIEIVLTIHCLLLLSSLFIGRAWLANKPSFKLKLLRFLLASCIISPIIVHCFNFDQKPERQNYVAFDALQQYARQPIF
KTESSKFNHGSSSAFTSMNVNYCQLLSVMFFLIVLFRSYHLLSGLGRLKLMLAEAIPYRTSGKLVIKISHHCHVPFSILL
FNKAYIVLPVSIFSSSMNVRIAIAHEGQHHRNGDCSWAYFIEIIRIIFFGNPGVTQWFRVLADLQELSCDEVLVGHQKIS
AHDYGHCLLQVVEAVSQCSLASNREITCTVGMALNKENEDCKFIIRRISMLTAYSPNASRPLLLGIVFAGFSILSPICVA
YSAAGSLTSSMVKEVDISHLDPRMQQIAERQITTAVKQYHAKSGVIAIADPQTGNIIAFAESSKNKGLESWKSRIFSPGS
TIKPFIAAAAINSGNSYETKNYDCHSPYYIAGKTFTNYSSNVESASLAEAIAKSINVCLIRVSQEAGVPVIRKKLTEFGF
DTSTWWQADRSDGLQLAMAALGENIPVTIESLIKSYAILANKGHSFDRGNSAIISETTNYSINHMLENAVTNGTGKLAVI
PGVSVAGKTGTVIENNDKYLALFAGYVPADNPRYVVLVVIEEGHFSKNGKTLVSGGELAAPVFRNVAMDALISVNQ
>Mature_636_residues
MLLIEIVLTIHCLLLLSSLFIGRAWLANKPSFKLKLLRFLLASCIISPIIVHCFNFDQKPERQNYVAFDALQQYARQPIF
KTESSKFNHGSSSAFTSMNVNYCQLLSVMFFLIVLFRSYHLLSGLGRLKLMLAEAIPYRTSGKLVIKISHHCHVPFSILL
FNKAYIVLPVSIFSSSMNVRIAIAHEGQHHRNGDCSWAYFIEIIRIIFFGNPGVTQWFRVLADLQELSCDEVLVGHQKIS
AHDYGHCLLQVVEAVSQCSLASNREITCTVGMALNKENEDCKFIIRRISMLTAYSPNASRPLLLGIVFAGFSILSPICVA
YSAAGSLTSSMVKEVDISHLDPRMQQIAERQITTAVKQYHAKSGVIAIADPQTGNIIAFAESSKNKGLESWKSRIFSPGS
TIKPFIAAAAINSGNSYETKNYDCHSPYYIAGKTFTNYSSNVESASLAEAIAKSINVCLIRVSQEAGVPVIRKKLTEFGF
DTSTWWQADRSDGLQLAMAALGENIPVTIESLIKSYAILANKGHSFDRGNSAIISETTNYSINHMLENAVTNGTGKLAVI
PGVSVAGKTGTVIENNDKYLALFAGYVPADNPRYVVLVVIEEGHFSKNGKTLVSGGELAAPVFRNVAMDALISVNQ

Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=334, Percent_Identity=26.0479041916168, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 69934; Mature: 69934

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIEIVLTIHCLLLLSSLFIGRAWLANKPSFKLKLLRFLLASCIISPIIVHCFNFDQKP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ERQNYVAFDALQQYARQPIFKTESSKFNHGSSSAFTSMNVNYCQLLSVMFFLIVLFRSYH
CCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LLSGLGRLKLMLAEAIPYRTSGKLVIKISHHCHVPFSILLFNKAYIVLPVSIFSSSMNVR
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCEEEEEEHHHHCCCCCEE
IAIAHEGQHHRNGDCSWAYFIEIIRIIFFGNPGVTQWFRVLADLQELSCDEVLVGHQKIS
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCC
AHDYGHCLLQVVEAVSQCSLASNREITCTVGMALNKENEDCKFIIRRISMLTAYSPNASR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
PLLLGIVFAGFSILSPICVAYSAAGSLTSSMVKEVDISHLDPRMQQIAERQITTAVKQYH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHH
AKSGVIAIADPQTGNIIAFAESSKNKGLESWKSRIFSPGSTIKPFIAAAAINSGNSYETK
HCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCC
NYDCHSPYYIAGKTFTNYSSNVESASLAEAIAKSINVCLIRVSQEAGVPVIRKKLTEFGF
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHCC
DTSTWWQADRSDGLQLAMAALGENIPVTIESLIKSYAILANKGHSFDRGNSAIISETTNY
CCCHHCCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
SINHMLENAVTNGTGKLAVIPGVSVAGKTGTVIENNDKYLALFAGYVPADNPRYVVLVVI
HHHHHHHHHHCCCCCCEEEECCCEECCCCCCEEECCCCEEEEEECCCCCCCCCEEEEEEE
EEGHFSKNGKTLVSGGELAAPVFRNVAMDALISVNQ
ECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLIEIVLTIHCLLLLSSLFIGRAWLANKPSFKLKLLRFLLASCIISPIIVHCFNFDQKP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ERQNYVAFDALQQYARQPIFKTESSKFNHGSSSAFTSMNVNYCQLLSVMFFLIVLFRSYH
CCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LLSGLGRLKLMLAEAIPYRTSGKLVIKISHHCHVPFSILLFNKAYIVLPVSIFSSSMNVR
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCEEEEEEHHHHCCCCCEE
IAIAHEGQHHRNGDCSWAYFIEIIRIIFFGNPGVTQWFRVLADLQELSCDEVLVGHQKIS
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCC
AHDYGHCLLQVVEAVSQCSLASNREITCTVGMALNKENEDCKFIIRRISMLTAYSPNASR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
PLLLGIVFAGFSILSPICVAYSAAGSLTSSMVKEVDISHLDPRMQQIAERQITTAVKQYH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHH
AKSGVIAIADPQTGNIIAFAESSKNKGLESWKSRIFSPGSTIKPFIAAAAINSGNSYETK
HCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCC
NYDCHSPYYIAGKTFTNYSSNVESASLAEAIAKSINVCLIRVSQEAGVPVIRKKLTEFGF
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHCC
DTSTWWQADRSDGLQLAMAALGENIPVTIESLIKSYAILANKGHSFDRGNSAIISETTNY
CCCHHCCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
SINHMLENAVTNGTGKLAVIPGVSVAGKTGTVIENNDKYLALFAGYVPADNPRYVVLVVI
HHHHHHHHHHCCCCCCEEEECCCEECCCCCCEEECCCCEEEEEECCCCCCCCCEEEEEEE
EEGHFSKNGKTLVSGGELAAPVFRNVAMDALISVNQ
ECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3126399 [H]