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The map label for this gene is mta [H]

Identifier: 148359146

GI number: 148359146

Start: 1845835

End: 1846782

Strand: Reverse

Name: mta [H]

Synonym: LPC_1038

Alternate gene names: 148359146

Gene position: 1846782-1845835 (Counterclockwise)

Preceding gene: 148359147

Following gene: 148359145

Centisome position: 51.64

GC content: 38.19

Gene sequence:

>948_bases
ATGACACAATGGTTCGTAAAAGATTTAAGCCAATTAACTGGTGTATCGGTACAAACGTTACATCACTATGACCGTATAGG
ATTGCTAAAGCCTTCATTACGACTTGCCAATGGGTACCGTGTTTACTCTGAGAAGGATTTATTGAAATTACAACAGATTA
TTGCTTTGAAGTTTTTCGGTTTTGAGTTGTCACAAATCAAAACCTTACTCGCTGAAGAAGGTAATGCGCTCAATCATTTT
AACAGCCAAGCTCAGGTGTTAGAACAAAAAGCATCCACTTTACTTGAGGGAGCTAAAACTTTGAGACGCATCATTGACTC
TGTTGACAAAAATCAATCTATCCCTTGGGAAACCATTATTCAACTTATAGAGGTATATAAAATGACAGAACATCTTGAGC
ATGGCTGGGTAAAGGAAATATTCACGCCGGATGAATTAAAACAGTACGCTGAGTTTGAAAAAGAAATGAAAGCCAATGCC
ACGCCTGAGCAAAAAGCGGCTATGGAAAACAATTGGTCTCAGCTAGTTGATGAGATAAAAAATAATCTGAAGCAAGATCC
AGGCTCAAAAATAGGAATTTATTTAGGAAAGAAGATTATGGATTGGGTTAATGGGGTCTACGGTAAAAAATATGCCCATT
TAAGGACCAAAAAATTTGAACAGGGTTTTGGGGAAGGAAAAGGTCTTGATGAGGTTGGATTAACACCTGAAATCGTATCC
TGGATGGATAAAGCGATGGATGCTTACTGGCGAGACAGAATCTATGGGATTCTTGATCAAGTAGGAAAAGTTCCTTCACC
AAGCGTATTAGCTCTTTGGAATGAGATGCTGGTTGATATGTATGGTGAGGAAACATCGCGTAAAAACGCCATATATGAAA
TTGCTTTAAATGATGATCAGGTTAGTCCTGAGGCAAAAGCCTGGCTTAGAAATCTTTTAGATTCCTAA

Upstream 100 bases:

>100_bases
CTCTTGGTAGGTTAGAAAAATAATGGCTCAAGAAATTTTAAAAACTGCTTGACCCTATTGTTGCTATAGGCATTACCTTT
GTCTTGAAGGGGGAAACACA

Downstream 100 bases:

>100_bases
AAATATGAATAACACTGTTGGATCGGTATTGTTTTACCGATCCATTCGACTCGATTTGATACCTTCAATTATTAATTGAT
TTAGCATCTTAGGCAGACCA

Product: MerR family transporter transcriptional regulator

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTQWFVKDLSQLTGVSVQTLHHYDRIGLLKPSLRLANGYRVYSEKDLLKLQQIIALKFFGFELSQIKTLLAEEGNALNHF
NSQAQVLEQKASTLLEGAKTLRRIIDSVDKNQSIPWETIIQLIEVYKMTEHLEHGWVKEIFTPDELKQYAEFEKEMKANA
TPEQKAAMENNWSQLVDEIKNNLKQDPGSKIGIYLGKKIMDWVNGVYGKKYAHLRTKKFEQGFGEGKGLDEVGLTPEIVS
WMDKAMDAYWRDRIYGILDQVGKVPSPSVLALWNEMLVDMYGEETSRKNAIYEIALNDDQVSPEAKAWLRNLLDS

Sequences:

>Translated_315_residues
MTQWFVKDLSQLTGVSVQTLHHYDRIGLLKPSLRLANGYRVYSEKDLLKLQQIIALKFFGFELSQIKTLLAEEGNALNHF
NSQAQVLEQKASTLLEGAKTLRRIIDSVDKNQSIPWETIIQLIEVYKMTEHLEHGWVKEIFTPDELKQYAEFEKEMKANA
TPEQKAAMENNWSQLVDEIKNNLKQDPGSKIGIYLGKKIMDWVNGVYGKKYAHLRTKKFEQGFGEGKGLDEVGLTPEIVS
WMDKAMDAYWRDRIYGILDQVGKVPSPSVLALWNEMLVDMYGEETSRKNAIYEIALNDDQVSPEAKAWLRNLLDS
>Mature_314_residues
TQWFVKDLSQLTGVSVQTLHHYDRIGLLKPSLRLANGYRVYSEKDLLKLQQIIALKFFGFELSQIKTLLAEEGNALNHFN
SQAQVLEQKASTLLEGAKTLRRIIDSVDKNQSIPWETIIQLIEVYKMTEHLEHGWVKEIFTPDELKQYAEFEKEMKANAT
PEQKAAMENNWSQLVDEIKNNLKQDPGSKIGIYLGKKIMDWVNGVYGKKYAHLRTKKFEQGFGEGKGLDEVGLTPEIVSW
MDKAMDAYWRDRIYGILDQVGKVPSPSVLALWNEMLVDMYGEETSRKNAIYEIALNDDQVSPEAKAWLRNLLDS

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 36188; Mature: 36057

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQWFVKDLSQLTGVSVQTLHHYDRIGLLKPSLRLANGYRVYSEKDLLKLQQIIALKFFG
CCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCEEECCHHHHHHHHHHHHHHHHC
FELSQIKTLLAEEGNALNHFNSQAQVLEQKASTLLEGAKTLRRIIDSVDKNQSIPWETII
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QLIEVYKMTEHLEHGWVKEIFTPDELKQYAEFEKEMKANATPEQKAAMENNWSQLVDEIK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHH
NNLKQDPGSKIGIYLGKKIMDWVNGVYGKKYAHLRTKKFEQGFGEGKGLDEVGLTPEIVS
HHHHCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
WMDKAMDAYWRDRIYGILDQVGKVPSPSVLALWNEMLVDMYGEETSRKNAIYEIALNDDQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
VSPEAKAWLRNLLDS
CCHHHHHHHHHHHCC
>Mature Secondary Structure 
TQWFVKDLSQLTGVSVQTLHHYDRIGLLKPSLRLANGYRVYSEKDLLKLQQIIALKFFG
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCEEECCHHHHHHHHHHHHHHHHC
FELSQIKTLLAEEGNALNHFNSQAQVLEQKASTLLEGAKTLRRIIDSVDKNQSIPWETII
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QLIEVYKMTEHLEHGWVKEIFTPDELKQYAEFEKEMKANATPEQKAAMENNWSQLVDEIK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHH
NNLKQDPGSKIGIYLGKKIMDWVNGVYGKKYAHLRTKKFEQGFGEGKGLDEVGLTPEIVS
HHHHCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
WMDKAMDAYWRDRIYGILDQVGKVPSPSVLALWNEMLVDMYGEETSRKNAIYEIALNDDQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
VSPEAKAWLRNLLDS
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]