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The map label for this gene is pabB [H]

Identifier: 148359091

GI number: 148359091

Start: 1786763

End: 1788085

Strand: Reverse

Name: pabB [H]

Synonym: LPC_0979

Alternate gene names: 148359091

Gene position: 1788085-1786763 (Counterclockwise)

Preceding gene: 148359098

Following gene: 148359090

Centisome position: 50.0

GC content: 37.41

Gene sequence:

>1323_bases
TTGATTGATAGTACTCTTATTACACTTGACTACCATGATTTTTCATCTGAATCCTATGAAAAACTCAGTCGTTTACCTGG
ATTTGTCCTGCTTCAGAGTACAGACAAGTCAACGGGGCGTTATGATATTTTAAGTGCTCACCCATATGAGAGGATGGTAA
TTGAGAATAATGTATATGATAAAGATTTAGTATTAACGAAATTAAAAAATAAACTAAAAATAGAGCAGTCAGAATTTGAT
CTTCCTTTTCAGGGCGGAGCCATAGGCTACGTTTCATACGACTTTGGTGCACTACTACATGATCATGAGCTATATCCACA
AAAAGATCTGGCGCATATACCTGTTTTAAATTTCGGGTTTTATGATTGGGCTATCATAGTTGATCACCATTTAAAAAAGG
CCACTTTATTTGCAAGAAACAGTCATTCTTCAACCAAAAGCGTTGTAGATGAAATAAAGAATATATTGAATAATCAATCC
ACAAAATCGGTACAATTTTCAGTTCAATCTGAATTTTTGCCATTAATATCAAGAGATAATTACAGAAACTCATTCAATGC
CATTCAACAAGCCCTGAGAACAGGACGCTCTTATCAGGTTAATTTCACGCAACCGTTTCAAACAAAATTCACCGGGGATC
CCTGGGATATGTACCAAAGGGTTAACAAAAATAACCCTGTCCCCTATGCTGCTTTTATCAGAACTGAGGAAGCTGACGTA
TTGAGCTTTTCTCCCGAACGATTTTTACTTTATGACAACGGTGAGATGTTAACTTCGCCCATAAAAGGCACTATCCACCG
ATCGAAAGATCCTGTTGTAGATAAAAAATTAAAAGAACAGTTATTAAACTGTCCTAAAAACAGGGCTGAAAATGTCATGA
TTGTCGACTTGCTAAGAAACGATCTAGGGAAACTTGCCAAGGCTGACAGCGTAAAAGTAATGAGTCTTTGTAACATCCAG
AGCTTCAATGCAGTACATCATTTGGTTTCCGACATAAGAGCTCTTTGCAAAGAGGATATTCATCCAATTGAGGCATTTTT
CTCCTGTTTTCCAGGCGGTTCAATTACCGGGGCGCCTAAATTAGAAACGATGAAAATTATCAGTGAACAGGAAACCTATA
AAAGAGGGGTCTATTGTGGTTGTATAGCCTATTTTTCACAACATGGCCGTTTCGATGCCAATATCGCGATACGTACGGTG
ACAGCCAAGGATAATGTTTTGTATTTGGCAGCAGGAGGGGGAATAGTTATTGACTCCGATTGGGAAGATGAATATCGTGA
ATGTTTAACCAAAATTAGTGCAATTATCAATGGAATCAAATAA

Upstream 100 bases:

>100_bases
AAGATAAAAATATACGTTTTTTATTGATAAGTTAGGTTAAAATGACCAAATGAAAAGCATTGCATTTTTTCACAGCACAT
CCTTATCTTGAGGTGATAAT

Downstream 100 bases:

>100_bases
TACCCAACAGTCAATCAAAACACATTCATCAGTTATCGTTTTATATGATCTTTCCAAAGACTCGTTAATTCTCACCAAGC
GAAGTCAGATGCTTAATAAA

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIDSTLITLDYHDFSSESYEKLSRLPGFVLLQSTDKSTGRYDILSAHPYERMVIENNVYDKDLVLTKLKNKLKIEQSEFD
LPFQGGAIGYVSYDFGALLHDHELYPQKDLAHIPVLNFGFYDWAIIVDHHLKKATLFARNSHSSTKSVVDEIKNILNNQS
TKSVQFSVQSEFLPLISRDNYRNSFNAIQQALRTGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADV
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLNCPKNRAENVMIVDLLRNDLGKLAKADSVKVMSLCNIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECLTKISAIINGIK

Sequences:

>Translated_440_residues
MIDSTLITLDYHDFSSESYEKLSRLPGFVLLQSTDKSTGRYDILSAHPYERMVIENNVYDKDLVLTKLKNKLKIEQSEFD
LPFQGGAIGYVSYDFGALLHDHELYPQKDLAHIPVLNFGFYDWAIIVDHHLKKATLFARNSHSSTKSVVDEIKNILNNQS
TKSVQFSVQSEFLPLISRDNYRNSFNAIQQALRTGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADV
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLNCPKNRAENVMIVDLLRNDLGKLAKADSVKVMSLCNIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECLTKISAIINGIK
>Mature_440_residues
MIDSTLITLDYHDFSSESYEKLSRLPGFVLLQSTDKSTGRYDILSAHPYERMVIENNVYDKDLVLTKLKNKLKIEQSEFD
LPFQGGAIGYVSYDFGALLHDHELYPQKDLAHIPVLNFGFYDWAIIVDHHLKKATLFARNSHSSTKSVVDEIKNILNNQS
TKSVQFSVQSEFLPLISRDNYRNSFNAIQQALRTGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADV
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLNCPKNRAENVMIVDLLRNDLGKLAKADSVKVMSLCNIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECLTKISAIINGIK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=456, Percent_Identity=38.1578947368421, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1787518, Length=396, Percent_Identity=29.040404040404, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=23.8738738738739, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=388, Percent_Identity=30.6701030927835, Blast_Score=192, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6324361, Length=400, Percent_Identity=27, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49970; Mature: 49970

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSTLITLDYHDFSSESYEKLSRLPGFVLLQSTDKSTGRYDILSAHPYERMVIENNVYD
CCCCEEEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHEEEECCCCC
KDLVLTKLKNKLKIEQSEFDLPFQGGAIGYVSYDFGALLHDHELYPQKDLAHIPVLNFGF
HHHHHHHHHHHHEEEHHCCCCCCCCCEEEEEEECHHHHHCCCCCCCCCCCCCCCEEECCC
YDWAIIVDHHLKKATLFARNSHSSTKSVVDEIKNILNNQSTKSVQFSVQSEFLPLISRDN
CEEEEEEHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCC
YRNSFNAIQQALRTGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCE
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLNCPKNRAENVMIVDLLRN
EEECCCEEEEEECCCEEECCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHH
DLGKLAKADSVKVMSLCNIQSFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPK
HHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
LETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTVTAKDNVLYLAAGGGIVIDSD
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECEEEEEEEEECCCEEEEEECCCEEECCC
WEDEYRECLTKISAIINGIK
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIDSTLITLDYHDFSSESYEKLSRLPGFVLLQSTDKSTGRYDILSAHPYERMVIENNVYD
CCCCEEEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHEEEECCCCC
KDLVLTKLKNKLKIEQSEFDLPFQGGAIGYVSYDFGALLHDHELYPQKDLAHIPVLNFGF
HHHHHHHHHHHHEEEHHCCCCCCCCCEEEEEEECHHHHHCCCCCCCCCCCCCCCEEECCC
YDWAIIVDHHLKKATLFARNSHSSTKSVVDEIKNILNNQSTKSVQFSVQSEFLPLISRDN
CEEEEEEHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCC
YRNSFNAIQQALRTGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCE
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLNCPKNRAENVMIVDLLRN
EEECCCEEEEEECCCEEECCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHH
DLGKLAKADSVKVMSLCNIQSFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPK
HHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
LETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTVTAKDNVLYLAAGGGIVIDSD
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECEEEEEEEEECCCEEEEEECCCEEECCC
WEDEYRECLTKISAIINGIK
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]