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The map label for this gene is yfnA [H]

Identifier: 148358492

GI number: 148358492

Start: 388618

End: 389802

Strand: Reverse

Name: yfnA [H]

Synonym: LPC_0358

Alternate gene names: 148358492

Gene position: 389802-388618 (Counterclockwise)

Preceding gene: 148358493

Following gene: 148358491

Centisome position: 10.9

GC content: 37.97

Gene sequence:

>1185_bases
ATGCACTTAAAGCGAACTTTATCATTAACACTGCTAGCCTTTTATGGGCTTGGAACTATATTGGGCGCGGGAATTTATGC
CCTTGTCGGTGAGGTCGCAAAAGAAGCGGCACAATTTACCCCTCTATCATTCTTAATCGCATCCATCATCGCTCTTTTTA
CTGCCATTTCTTATGCAGAATTAAGCTCAAGGTTACCTCATAGCGCAGGTTCTGCTCTTTACGTGCGTAGGGCATTCCAT
CAAAAATGGCTATCTGGCCTAATAGGCTGGATCGTGGTCTTAACAGGTATCATTTCAGCAGCCACCCTATCCCATGGTTT
TGTCAAATATTTTCAATTGTTTTTGCCATTACCACCTTCTCTCATCATCACTATATTAACCGTCATTTTAGCTGGGGTTG
CTATTTGGGGTATTCGTGAATCAGCGACTCTTATCCTGTTCATGACGCTCATGGAAGTGGGTGGATTATTGATGATTATT
TATTACGGTCGTTATTCATTAGCTTCTATCGACATCAAATCCTTCTCTTTCCCTCATTCTTTTGATGGGGTGCTTATTGG
AGCTTTTATTGCTTTTTATGCTTTTATTGGTTTTGAAGATATGGTTAATACCGCAGAAGAAACAATAAATCCTGAAAAAA
CACTTCCAAAAGCTATTTTTCTTGCTTTAATATCCGCAACCATTTTATATATTGCAGTCGCCTGGGTTATCGTCTTGACC
ATACCATCCAATACTTTAGTCAAAACGGACATGCCCCTTATTGAAATTATTAAGCTTCAGGGACAATCTCCCTTGTTGTT
TTCAATCATTGCATTAATTTCTATTACCAATGGAATTCTGGTGCAAATTATTATGGCTTCACGGCTTATTTATGGTATGG
CCAATCAACAAAATGCCCCCCAAATATTCTCTTCTGTCTATTCCAAAACTCAAACACCAGTCTACTCGACCTTACTGGTA
TTTCTTATGATTTTACTTTTTGCCTATGCTCTCCCTATTACTACCCTAGCCAAATTAACCAGCAGTATCATATTGTGTAT
TTTTATCATCATTCATGCCTCGCTAATTAAAATCAAACTGACAGAGAAAAAACCAACAAACGCCATTTCATTCCCTATTG
TTTTCCCGATGATTTCGATTTTATTAACCCTGGCCTTTTTAATCATACAGTTTTTTTTAAAGTAG

Upstream 100 bases:

>100_bases
TTCACTATCTATCTGGTAACTGGCGAAAAATAAAAGAGGTAGCAAATAAAAAAGAAAATCCGTTCTACGACTATAGATCT
CCAGATAAAATGGGGGAGCG

Downstream 100 bases:

>100_bases
ATTATTTCTCATAAATTTTTAACCCGGTGTCATATAAATTTTGGGAATCAACAGAGTGATTGTCTGTTTTCAATTCGCTG
CTCCTCTGTGCCTGTATCCC

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MHLKRTLSLTLLAFYGLGTILGAGIYALVGEVAKEAAQFTPLSFLIASIIALFTAISYAELSSRLPHSAGSALYVRRAFH
QKWLSGLIGWIVVLTGIISAATLSHGFVKYFQLFLPLPPSLIITILTVILAGVAIWGIRESATLILFMTLMEVGGLLMII
YYGRYSLASIDIKSFSFPHSFDGVLIGAFIAFYAFIGFEDMVNTAEETINPEKTLPKAIFLALISATILYIAVAWVIVLT
IPSNTLVKTDMPLIEIIKLQGQSPLLFSIIALISITNGILVQIIMASRLIYGMANQQNAPQIFSSVYSKTQTPVYSTLLV
FLMILLFAYALPITTLAKLTSSIILCIFIIIHASLIKIKLTEKKPTNAISFPIVFPMISILLTLAFLIIQFFLK

Sequences:

>Translated_394_residues
MHLKRTLSLTLLAFYGLGTILGAGIYALVGEVAKEAAQFTPLSFLIASIIALFTAISYAELSSRLPHSAGSALYVRRAFH
QKWLSGLIGWIVVLTGIISAATLSHGFVKYFQLFLPLPPSLIITILTVILAGVAIWGIRESATLILFMTLMEVGGLLMII
YYGRYSLASIDIKSFSFPHSFDGVLIGAFIAFYAFIGFEDMVNTAEETINPEKTLPKAIFLALISATILYIAVAWVIVLT
IPSNTLVKTDMPLIEIIKLQGQSPLLFSIIALISITNGILVQIIMASRLIYGMANQQNAPQIFSSVYSKTQTPVYSTLLV
FLMILLFAYALPITTLAKLTSSIILCIFIIIHASLIKIKLTEKKPTNAISFPIVFPMISILLTLAFLIIQFFLK
>Mature_394_residues
MHLKRTLSLTLLAFYGLGTILGAGIYALVGEVAKEAAQFTPLSFLIASIIALFTAISYAELSSRLPHSAGSALYVRRAFH
QKWLSGLIGWIVVLTGIISAATLSHGFVKYFQLFLPLPPSLIITILTVILAGVAIWGIRESATLILFMTLMEVGGLLMII
YYGRYSLASIDIKSFSFPHSFDGVLIGAFIAFYAFIGFEDMVNTAEETINPEKTLPKAIFLALISATILYIAVAWVIVLT
IPSNTLVKTDMPLIEIIKLQGQSPLLFSIIALISITNGILVQIIMASRLIYGMANQQNAPQIFSSVYSKTQTPVYSTLLV
FLMILLFAYALPITTLAKLTSSIILCIFIIIHASLIKIKLTEKKPTNAISFPIVFPMISILLTLAFLIIQFFLK

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=414, Percent_Identity=24.8792270531401, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI258614005, Length=407, Percent_Identity=25.5528255528256, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI258614003, Length=407, Percent_Identity=25.5528255528256, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI181337167, Length=337, Percent_Identity=28.486646884273, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI258645169, Length=407, Percent_Identity=25.0614250614251, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI110347453, Length=346, Percent_Identity=31.5028901734104, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI114326544, Length=209, Percent_Identity=26.7942583732057, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI114326550, Length=209, Percent_Identity=26.7942583732057, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI115648063, Length=420, Percent_Identity=25.2380952380952, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI115648022, Length=420, Percent_Identity=25.2380952380952, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910308, Length=420, Percent_Identity=24.7619047619048, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI186910306, Length=420, Percent_Identity=24.7619047619048, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI186910304, Length=420, Percent_Identity=24.7619047619048, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786694, Length=362, Percent_Identity=25.1381215469613, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082250, Length=350, Percent_Identity=24.5714285714286, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082023, Length=348, Percent_Identity=27.0114942528736, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786302, Length=417, Percent_Identity=23.5011990407674, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081869, Length=332, Percent_Identity=22.5903614457831, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789017, Length=387, Percent_Identity=21.9638242894057, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790653, Length=329, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786789, Length=418, Percent_Identity=24.4019138755981, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786602, Length=346, Percent_Identity=23.9884393063584, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=391, Percent_Identity=26.5984654731458, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17531343, Length=390, Percent_Identity=26.6666666666667, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17533459, Length=393, Percent_Identity=26.2086513994911, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32566699, Length=309, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=419, Percent_Identity=23.3890214797136, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24667468, Length=409, Percent_Identity=25.9168704156479, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI221512776, Length=405, Percent_Identity=22.962962962963, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24666159, Length=405, Percent_Identity=22.962962962963, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24668806, Length=415, Percent_Identity=26.0240963855422, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21356285, Length=415, Percent_Identity=26.0240963855422, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24668802, Length=415, Percent_Identity=26.0240963855422, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI161077963, Length=363, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281366235, Length=399, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007820, Length=399, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007818, Length=275, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI85725152, Length=275, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550968, Length=346, Percent_Identity=26.5895953757225, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921172, Length=346, Percent_Identity=26.5895953757225, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 43196; Mature: 43196

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLKRTLSLTLLAFYGLGTILGAGIYALVGEVAKEAAQFTPLSFLIASIIALFTAISYAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSSRLPHSAGSALYVRRAFHQKWLSGLIGWIVVLTGIISAATLSHGFVKYFQLFLPLPPS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LIITILTVILAGVAIWGIRESATLILFMTLMEVGGLLMIIYYGRYSLASIDIKSFSFPHS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEHHCCCCCCC
FDGVLIGAFIAFYAFIGFEDMVNTAEETINPEKTLPKAIFLALISATILYIAVAWVIVLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPSNTLVKTDMPLIEIIKLQGQSPLLFSIIALISITNGILVQIIMASRLIYGMANQQNAP
CCCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QIFSSVYSKTQTPVYSTLLVFLMILLFAYALPITTLAKLTSSIILCIFIIIHASLIKIKL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
TEKKPTNAISFPIVFPMISILLTLAFLIIQFFLK
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHLKRTLSLTLLAFYGLGTILGAGIYALVGEVAKEAAQFTPLSFLIASIIALFTAISYAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSSRLPHSAGSALYVRRAFHQKWLSGLIGWIVVLTGIISAATLSHGFVKYFQLFLPLPPS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LIITILTVILAGVAIWGIRESATLILFMTLMEVGGLLMIIYYGRYSLASIDIKSFSFPHS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEHHCCCCCCC
FDGVLIGAFIAFYAFIGFEDMVNTAEETINPEKTLPKAIFLALISATILYIAVAWVIVLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPSNTLVKTDMPLIEIIKLQGQSPLLFSIIALISITNGILVQIIMASRLIYGMANQQNAP
CCCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QIFSSVYSKTQTPVYSTLLVFLMILLFAYALPITTLAKLTSSIILCIFIIIHASLIKIKL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
TEKKPTNAISFPIVFPMISILLTLAFLIIQFFLK
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]